Navigation Links
Leading researchers to reveal comprehensive dos and don'ts for prostate cancer
Date:10/13/2007

Lake Tahoe, CA, October 13, 2007Today at the Prostate Cancer Foundations Annual Scientific Retreat, researchers will share new findings on how eating common foods such as tomatoes and fish, maintaining a healthy weight, and avoiding meats cooked at high temperatures may help prevent prostate cancer, and help men live healthier and longer after diagnosis. One in six men will be diagnosed with prostate cancer in their lifetime, and an estimated 218,890 cases will occur in The United States this year.

Since the 1980s, researchers have hypothesized that nutrition choices could be connected to prostate cancer. Today, those ideas are being substantiated by more widespread studies, in combination with newer technologies in gene research.

There are strong indicators in our research that diet and lifestyle are very important with this particular form of cancer, said Meir Stampfer, M.D., Professor of Epidemiology and Nutrition, Harvard School of Public Health. When we look at men from other cultures like in Asia, the rates of prostate cancer are significantly lower than in the U.S. Yet when these same men move here, within one generation, the rates increase very rapidly. We believe there is a clear correlation to how we live and eat.

June Chan, ScD, of the University of California San Francisco, has been studying the potential impact of fish oil and tomato extracts on the prostate gland prior to and after exposure. What were trying to determine is if men with low grade prostate cancer can manage their disease with these kinds of nutritional interventions and delay or avoid the need for more aggressive treatments, all of which carry a risk of side effects that can adversely affect physical function and quality of life, said Chan. In combination with other studies, the potential we see for these everyday supplements or foods to help men avoid or delay treatment is promising.

This type of approach, often deemed active surveillance, is a prostate cancer disease management option that monitors prostate-specific antigen (PSA) levels as well as the grade and stage of the tumor until a more aggressive treatment option may become necessary. One-quarter to one-half of all cases of diagnosed prostate cancer in the U.S. and Europe are considered candidates for this kind of approach, which researchers hope leads to better outcomes for patients with low-risk disease. One aspect of this management approach may include specific dietary modifications such as minimizing intake of red, processed or well-done meats.

Angelo De Marzo, M.D., Ph.D., along with colleague William G. Nelson M.D., Ph.D. of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, have been studying one of the most high profile issues around diet and prostate cancer: dont overheat your meat. Weve known since the 1980s that ingesting meat cooked at very high temperatures can cause cellular mutations, some of which can lead specifically to prostate cancer. What weve found now in the rodent prostate is that the specific areas within the organ that develop cancer after exposure to the meat compounds also first become inflamed and develop a form of atrophy that resembles damaged areas in the human prostate that are likely a very early indicator of a problem. According to De Marzo, if scientists can develop markers of damage and dietary exposures it may be possible for doctors to intervene before cancer ever develops in the prostate.

De Marzo also has some practical advice: If youre going to eat meat cooked at high temperatures, like I still enjoy, flip your hamburgers more often so the outside does not burn, marinate the meat in ingredients (such as teriyaki sauce) that dont create a crust, precook it in the microwave, or at the least scrape off the charred material. De Marzo also suggests replacing chicken, beef, veal or lamb with soy protein or fish, taking a page from the Asian diet where disease rates are very low. We need to be realistic: you can help reduce your chance of developing prostate cancer without becoming a vegetarian.

With more widespread testing for prostate cancer using the common PSA test, increasing numbers of new cases are being tracked. The resulting volume of patients, many of whom may have less virulent forms of prostate cancer, is creating a challenge for physicians determined to provide patients with the most appropriate advice which may not always include aggressive treatment.

Thanks to funding from the Prostate Cancer Foundation and others like the National Cancer Institute, were getting closer every day to developing the best protocols for thousands of men with this diagnosis, said Stampfer. Our goal is that any man with low risk prostate cancer can make simple changes that will extend his life and that healthy men can avoid it altogether.


'/>"/>

Contact: Sharon Reis
sreis@gymr.com
202-745-5103
GYMR
Source:Eurekalert

Related biology news :

1. Enzyme allows B cells to resist death, leading to leukemia
2. Scientists document complex genomic events leading to the birth of new genes
3. Genetic links could unlock clues to leading cause of blindness
4. Leading scientists rank endangered dolphins, porpoises most in need of immediate action
5. Why do aneurysms form? New studies suggest leading role for white blood cells
6. Leading lampreys to slaughter: Pheromone for scourge of Great Lakes identified
7. Jefferson scientists identify gene defect leading to abnormal skin development and cancer
8. ORNL leading effort to help harness power of Shewanella
9. Leading reason for corneal transplants comes into focus
10. Twin studies reveal genetic components leading to cardiac and kidney disease
11. Climate change could trigger boom and bust population cycles leading to extinction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... and BANGALORE, India , April ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... today announced a global partnership that will provide ... to use mobile banking and payment services.      ... a key innovation area for financial services, but it also ...
(Date:4/19/2016)... UAE, April 20, 2016 The ... as a compact web-based "all-in-one" system solution for all ... fingerprint reader or the door interface with integration authorization ... access control systems. The minimal dimensions of the access ... into the building installations offer considerable freedom of design ...
(Date:4/13/2016)... 13, 2016  IMPOWER physicians supporting Medicaid patients in ... new clinical standard in telehealth thanks to a new ... higi platform, IMPOWER patients can routinely track key health ... mass index, and, when they opt in, share them ... to a local retail location at no cost. By ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... New Jersey and READING, ... Indegene ( http://www.indegene.com ), a leading ... to life science, pharmaceutical and healthcare organisations and ... of innovative scientific support throughout the product lifecycle, ... with the launch of IntraScience.      ...
(Date:5/26/2016)... Despite the volatility that continues to ... Today,s pre-market research on ActiveWallSt.com directs the investor community,s focus ... RDUS ), Cerus Corp. (NASDAQ: CERS ), ... Prime Therapeutics Inc. (NASDAQ: FPRX ). Register with ... http://www.activewallst.com/ On Wednesday, shares in ...
(Date:5/26/2016)... ... 26, 2016 , ... Kinder Scientific (KinderScientific.com), a leading animal ... the Company for the future. Kinder Scientific announces restructured ownership and additional ... appointed Chairman of the Board, Curtis D. Kinghorn has been appointed CEO/President and ...
(Date:5/25/2016)... San Diego, Calif. (PRWEB) , ... May 25, 2016 , ... ... San Diego area and has consistently been rated one of its top attractions. ... over the globe to participate in a unique and intimate team-building experience. , Each ...
Breaking Biology Technology: