Navigation Links
Layered approach may yield stronger, more successful bone implants
Date:8/17/2007

Researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST) have developed a new method for layering two kinds of biomaterials into one strong, yet porous unit that may lead to improved reconstruction or repair of bones.

Currently, calcium phosphate cements (CPCs)water-based pastes of powdered calcium and a phosphate compound that form hydroxyapatite, a material found in natural boneare used for reconstructing or repairing skeletal defects, but only in bones that are not load-bearing (such as those in the face and skull). Macropores built into the CPCs make it easier for new bone cells to infuse and, eventually, solidify the implant. Until this happens, however, the macropores leave the implant brittle and susceptible to failure.

In the September 2007 issue of Biomaterials,* Hockin Xu and colleagues describe a unique approach for providing the strength needed to help an implant better survive its early stages. First, a macroporous CPC paste is placed into the area needing reconstruction or repair. Then, a strong, fiber-reinforced CPC paste is layered onto the first CPC to support the new implant. Once new bone has grown into the macroporous layer and increased its strength, the absorbable fibers in the strong layer dissolve and create additional macroporous channels that promote even more bone tissue ingrowth. This method mimics the natural bone structure in which a strong layer, called cortical bone, covers and strengthens a weaker, macroporous layer (spongy bone).

The two pastes used in the layered CPC method harden in the bone cavity to form an implant that for the first time has both the porosity needed for bone growth and the integrity required for reconstruction or repair of load-bearing bones (such as jaws).

NIST and the ADAF have conducted cooperative research on dental and medical materials since 1928. ADAF researchers focus on development of new dental and biomedical materials, while NIST specializes in the development of improved technologies and methods for measuring materials properties.


'/>"/>

Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)
Source:Eurekalert

Related biology news :

1. A biosensor layered like lasagna
2. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
3. MSI releases moleculizer - a new approach to simulation of intracellular biochemical networks
4. Discovery Could Lead To Novel Approaches In HIV Treatment
5. New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines
6. Stopping smallpox in its tracks: A new anti-viral approach
7. New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal
8. Building a protein name dictionary from full text: a machine learning term extraction approach
9. NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma
10. Vaginal gel may provide a new approach to HIV prevention
11. Rensselaer researchers develop approach that predicts protein separation behavior
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2016)... , UAE, April 20, 2016 ... be implemented as a compact web-based "all-in-one" system solution ... the biometric fingerprint reader or the door interface with ... of modern access control systems. The minimal dimensions of ... ID readers into the building installations offer considerable freedom ...
(Date:4/14/2016)... 14, 2016 BioCatch ™, ... today announced the appointment of Eyal Goldwerger ... Goldwerger,s leadership appointment comes at a time ... the deployment of its platform at several of the ... which discerns unique cognitive and physiological factors, is a ...
(Date:3/31/2016)... March 31, 2016  Genomics firm Nabsys has completed ... Barrett Bready , M.D., who returned to the ... original technical leadership team, including Chief Technology Officer, ... Development, Steve Nurnberg and Vice President of Software and ... company. Dr. Bready served as CEO of ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016   Boston Biomedical ... novel compounds designed to target cancer stemness pathways, ... been granted Orphan Drug Designation from the U.S. ... of gastric cancer, including gastroesophageal junction (GEJ) cancer. ... designed to inhibit cancer stemness pathways by targeting ...
(Date:6/23/2016)... Prostate Cancer Foundation (PCF) is pleased to announce 24 new Young ... cancer. Members of the Class of 2016 were selected from a pool of ... More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... , ... June 23, 2016 , ... In a new ... in Denmark detail how a patient who developed lymphedema after being treated for breast ... results could change the paradigm for dealing with this debilitating, frequent side effect of ...
(Date:6/23/2016)... ... 23, 2016 , ... ClinCapture, the only free validated electronic ... showcase its product’s latest features from June 26 to June 30, 2016 for ... Disrupting Clinical Trials in The Cloud during the conference. DIA (Drug Information ...
Breaking Biology Technology: