Navigation Links
Lawson researchers share in $2.2 million grant
Date:8/30/2011

LONDON, ON Lawson Health Research Institute's Drs. Peter Cadieux and Hassan Razvi have been awarded just over $566,000 as part of a $2.2 million grant from the National Institutes of Health Research (NIH). With this funding, Cadieux and Razvi will explore the potential of novel coatings to significantly reduce bacterial adherence to urinary tract stents and catheters.

The grant was awarded in collaboration with Nerites Corporation Ltd., the producer of novel antimicrobial coatings. Although the coatings were originally developed to reduce bacterial build-up on orthopaedic implants and in dental equipment water lines, Drs. Cadieux and Razvi suspected they might have a similar urological potential. Through previous investigations, their research has shown that several of the coatings can prevent uropathogenic bacteria from attaching to device surfaces. For instance, their initial work with coated polyurethane demonstrated a greater than 99% reduction in the attachment of several bacteria common to urinary tract infections. This was followed by an animal study involving E. coli-infected rabbits, where 80% of those implanted with coated ureteral stent material cleared the infection in just three days compared to only 10% of control rabbits. These results suggest exciting possibilities for uteral health, with the potential to improve both prevention and treatment of urinary device-associated infections.

Over the next three years, Nerites Corporation will continue to improve upon their existing coatings while also developing new ones. Drs. Cadieux and Razvi will then assess them for bacterial resistance, biocompatibility and infection prevention properties, both at the lab bench and in animal models. To support this research, they plan to fund three graduate students through the Department of Microbiology and Immunology at the Schulich School of Medicine and Dentistry at The University of Western Ontario, and to engage Endourology research fellows at St. Joseph's Health Care London.

"Dr. Razvi and I are excited to continue this exceptional collaboration with Nerites Corporation," Dr. Cadieux says. "This funding will hopefully lead to the development and implementation of novel urinary tract device coatings for human clinical application that resist infection."


'/>"/>

Contact: Sonya Gilpin
sonya.gilpin@lawsonresearch.com
Lawson Health Research Institute
Source:Eurekalert

Related biology news :

1. Professor Dr. Alexander (Sandy) Lawson is awarded the 2011 Herman Skolnik Award
2. Lawson researchers take control of cancer
3. NC State researchers get to root of parasite genome
4. Researchers find animal with ability to survive climate change
5. Researchers find an essential gene for forming ears of corn
6. Researchers note differences between people and animals on calorie restriction
7. Researchers study acoustic communication in deep-sea fish
8. Researchers discover that growing up too fast may mean dying young in honey bees
9. Researchers study how pistachios may improve heart health
10. UI researchers find potentially toxic substance present in Chicago air
11. Researchers develop new self-training gene prediction program for fungi
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2016)... Calif. , Dec. 15, 2016   WaferGen ... publicly held genomics technology company, announced today that on ... Listing Qualifications Department of The Nasdaq Stock Market LLC ... closing bid price of WaferGen,s common stock had been ... Accordingly, WaferGen has regained compliance with Listing Rule 5550(a)(2) ...
(Date:12/15/2016)... "Increase in mobile transactions is driving the growth of ... expected to grow from USD 4.03 billion in 2015 ... of 29.3% between 2016 and 2022. The market is ... smart devices, government initiatives, and increasing penetration of e-commerce ... to grow at a high rate during the forecast ...
(Date:12/7/2016)... India , December 7, 2016 According to a ... Machine Learning), Software Tool (Facial Expression, Voice Recognition), Service, Application Area, End User, ... is estimated to grow from USD 6.72 Billion in 2016 to USD 36.07 ... Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... HACKENSACK, N.J. , Jan. 18, 2017   ... leading the fight to end Duchenne muscular dystrophy ... awarded to the New Jersey Institute of Technology (NJIT) ... ongoing exploration of robotic technology to assist ... study to incorporate NJIT,s technology – an embedded computer, ...
(Date:1/18/2017)... ... January 18, 2017 , ... Total Orthopedics ... implanted SpineFrontier’s A-CIFT™ Solofuse-P™. The operation took place on Wednesday, January 11, 2017 ... procedure was an anterior cervical discectomy and fusion on a 42 year old ...
(Date:1/18/2017)... ... January 18, 2017 , ... Announced ... Manufacturing Innovation Institutes (MII). U.S. Secretary of Commerce Penny Pritzker has announced the ... the Department of Defense has announced the award of a new Advanced Regenerative ...
(Date:1/18/2017)... , ... January 18, 2017 , ... Researchers from a new study are ... fall low enough after prostate cancer treatment, this indicates there is still remaining prostate cancer ... mortality. , “ The PSA test has always been an indicator of whether a man’s ...
Breaking Biology Technology: