Navigation Links
Lawson researcher sings the baby blues
Date:8/22/2012

LONDON, ON The impact of bipolar disorder during pregnancy has been hotly contended among the research community. Now, a new study from Lawson Health Research Institute and Western University is sorting out the debate and calling for more targeted, prospective research.

Bipolar disorder is characterized by depression, hypomania, or mania. It is most common among women, and its episodes are often concentrated during the height of the reproductive years.

Bipolar disorder can lead to suicide, infanticide, and increased risk for psychiatric hospitalization during the postpartum period. During pregnancy, though, the impact is unclear. Through a comprehensive literature review, Dr. Verinder Sharma and his team sought to clearly define what scientists already knew about bipolar disorder during pregnancy, and where they should look next.

Despite contradictory findings, their review suggests pregnancy could have a positive impact on bipolar disorder. Throughout the literature, bipolar II disorder was either uncommon or in remission during pregnancy. Women already diagnosed with bipolar disorder had fewer and shorter episodes while pregnant. Pregnant women also had a lower risk of any other mood disorder than non-pregnant women.

However, the impact of mood stabilizer medications has complicated much of the existing data. In the literature, bipolar disorder is often misdiagnosed as depression, and antidepressants are prescribed as treatment. These medications are known to make bipolar symptoms worse. Similarly, many women taking mood stabilizers discontinue their prescriptions to avoid potential side effects on their unborn babies. This rapid break appears to provoke bipolar episodes.

These circumstances have made it challenging for scientists to separate the impact of the drugs from the impact of the disorder. To make a clear judgment, Dr. Sharma is calling for large, multicenter, prospective studies that specifically address the natural course of the disorder.

"There is no period in a woman's life when the risk of relapse of bipolar disorder is as high as in the postpartum period. This is in sharp contrast to pregnancy, when women may experience an improvement in their symptoms," he says. "If we fail to understand the effect of pregnancy on bipolar disorder, we will fail to understand bipolar disorder."


'/>"/>
Contact: Sonya Gilpin
sonya.gilpin@lawsonresearch.com
519-685-8500 x75852
Lawson Health Research Institute
Source:Eurekalert

Related biology news :

1. Lawson recieves Grand Challenges Explorations grant for groundbreaking research
2. ORNL researchers improve soil carbon cycling models
3. Researchers identify key culprit causing muscle atrophy
4. Notre Dame researcher is shedding light on how jaws evolve
5. Researchers demonstrate control of devastating cassava virus in Africa
6. Rutgers-Camden genetics researcher receives NSF CAREER Award
7. WSU researcher sees how forests thrive after fires and volcanoes
8. Researchers pursue red flag for schizophrenia relapse
9. A new line of defense: Researchers find cattle vaccine works to reduce E. coli O157:H7
10. Queens researcher finds situation dire for threatened rhino species
11. Iowa State, Ames Lab researchers invent new tool to study single biological molecules
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... -- The Controller General of Immigration from Maldives Mr. ... have received the prestigious international IAIR Award for the most innovative high ... ... Maldives Immigration Controller ... (small picture on the right) have received the IAIR award for the ...
(Date:3/23/2017)... , Mar. 23, 2017 Research and Markets ... Market Analysis & Trends - Industry Forecast to 2025" report ... ... at a CAGR of around 8.8% over the next decade to ... report analyzes the market estimates and forecasts for all the given ...
(Date:3/22/2017)... , March 21, 2017 Vigilant ... company serving law enforcement agencies, announced today the appointment ... as director of public safety business development. ... law enforcement experience, including a focus on the aviation ... his most recent position, Mr. Sheridan served as the ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... (PRWEB) , ... August 16, 2017 , ... While art ... are much more closely connected than one might think. A Mesh Is Also ... open at the University City Science Center’s Esther Klein Gallery (EKG) on August 17 ...
(Date:8/15/2017)... After spending the past two years building a state-of-the-art technology which ... offers this platform to healthcare stakeholders (hospitals, foundations, biopharma companies etc.) ... collection vis a vis their members, under their own brand. Three ... offer. ... ...
(Date:8/15/2017)... ... August 15, 2017 , ... Kenall, a ... downlights designed to stay tightly sealed and perform efficiently for years. The downlights ... location listings just aren't enough, such as: hospitals; behavioral health facilities; cleanrooms; containment ...
(Date:8/14/2017)... Oregon (PRWEB) , ... August 14, 2017 , ... ... that provide essential device-to-computer interconnect using USB or PCI Express, announced the release ... , SYZYGY is intended to satisfy the need for a compact, low cost, ...
Breaking Biology Technology: