Navigation Links
Last sample collected for one of the world's 'deepest' biobanks

Montreal, October 22, 2010 This week, the last questionnaire was filled out and the final vial of blood was drawn, closing CARTaGENE's first ambitious goal of collecting samples and data from 20 000 Quebecers. With this last recruit, the CARTaGENE Universit of Montral research project has emerged as one the world's most comprehensive and powerful resources for providing an epidemiological snapshot of the health of its participants. This biobank data will be available as a resource to researchers worldwide and will provide greater insight into chronic health conditions such as cardiovascular disease, diabetes and cancer.

"We are extremely pleased that we've met this milestone and are grateful to all the participants who contributed to our project," says Philip Awadalla, CARTaGENE Scientific Director and a professor at the Universit of Montral. "Although there are few biobanks that are larger, ours is the first of its size to collect such extensive data for every participant, which makes it a very valuable scientific resource. In addition the CARTaGENE database is unique in that all the samples were collected the same way and that all the recruits went through the same interviews. This consistency is essential to making it such a precious resource. Data captured from this snapshot of the Quebec population gathered information from participants of many ethnic backgrounds. In addition, the unique French-Canadian population allows scientists to evaluate the impact of genealogies on health. We have already had requests for CARTaGENE data, a testimony to the database's value."

"The success of this first phase is an indicator of society's interest in knowledge," adds Guy Rouleau, Co-Principal Investigator, a Universit de Montral professor, and director of the Sainte-Justine University Hospital Research Center. "This database provides information on many of the principle determinants of health, such as the impact of lifestyle, genetics, environment and nutrition. Such a resource will allow physicians and scientists to better determine how to prevent disease and promote health. "

Sampling from the middle-aged population

The objective of CARTaGeNE was to create a public resource for research projects. Individuals aged 40 to 69 living in Montreal, Sherbrooke, Saguenay (Chicoutimi) and Quebec City metropolitan areas - were targeted. The information from the 20 000 participants will provide an accurate portrait of the Quebec metropolitan population's health and genetic diversity.

Participants were asked to complete a health questionnaire and interview with a nurse, and to give samples of urine, serum and blood. A small fraction of the samples will be used for initial analyses but most will be stored in the GQ-CAURC Biobank. Physical measurements, such as weight, waist and hips circumference, bone density, arterial pressure and stiffness were also taken. Participants were also invited during the consent process to indicate if they wanted to be contacted again or if they wish to participate in the CARTaGENE genealogical option by answering another questionnaire at home. Bartha Knoppers, a McGill University Professor of Medicine and Director of the HumGen project, and Claude Laberge, a University of Laval Genetics professor were the the original principal investigators of the project and are members of the CARTaGENE team.

"Our next steps are to enhance the data," says Awadalla. "Working with our sister biobanks across Canada, we are following up participants to evaluate individual lifestyle impacts on health such as nutrition, residential and occupational history. We are also exploring how environment impacts how individuals genes are regulated, and the impact of this variation on chronic disease."

Randomly recruiting participants is key to understanding how the genome of each human being interacts with the environment to determine ones health status. The science of genomics is devoted to studying genomes and their interaction with environmental factors that influence our health. CARTaGENE is the largest project to date on the genome of the population of Qubec.


Contact: Julie Gazaille
University of Montreal

Related biology news :

1. U-M researchers receive largest single collection of psoriasis DNA samples
2. Pressure testing tiny cell samples
3. Genetic patterns rise from huge yeast samples
4. Proposed mission would return sample from asteroid time capsule
5. No muss, no fuss miniaturized analysis for complex samples developed
6. UniPixel Announces Availability of Opcuity(TM) Finger Print Resistant Film Test Samples
7. Tiny samples could yield big predictive markers for pancreatic cancer
8. Electricity collected from the air could become the newest alternative energy source
9. New book reviews ancient and modern worlds of RNA
10. British scientific expedition discovers worlds deepest known undersea volcanic vents
11. Expedition heads for worlds deepest undersea volcanoes
Post Your Comments:
(Date:10/29/2015)... Mich. , Oct. 29, 2015  Rubicon ... Genomics for U.S. distribution of its DNA library ... kit and Rubicon,s new ThruPLEX Plasma-seq kit. ThruPLEX ... enable the preparation of NGS libraries for liquid ... for diagnostic and prognostic applications in cancer and ...
(Date:10/27/2015)... 27, 2015 In the present market scenario, ... for various industry verticals such as banking, healthcare, defense, ... growing demand for secure & simplified access control and ... as hacking of bank accounts, misuse of users, , ... as PC,s, laptops, and smartphones are expected to provide ...
(Date:10/26/2015)... and LAS VEGAS , Oct. 26, ... , an innovator in modern authentication and a founding ... the launch of its latest version of the Nok ... organizations to use standards-based authentication that supports existing and ... Authentication Suite is ideal for organizations deploying customer-facing applications ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  PharmAthene, Inc. (NYSE ... has adopted a stockholder rights plan (Rights Plan) in ... operating loss carryforwards (NOLs) under Section 382 of the ... --> PharmAthene,s use of its NOLs could ... change" as defined in Section 382 of the Code. ...
(Date:11/25/2015)... -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today ... Neurocrine Biosciences, will be presenting at the 27th Annual ... . .   Listeners ... prior to the presentation to download or install any ... available on the website approximately one hour after the ...
(Date:11/25/2015)... 25, 2015 The Global ... a professional and in-depth study on the current ... (Logo: ) , The ... including definitions, classifications, applications and industry chain structure. ... international markets including development trends, competitive landscape analysis, ...
(Date:11/24/2015)... Cepheid (NASDAQ: CPHD ) today announced ... conference, and invited investors to participate via webcast. ... December 1, 2015 at 11.00 a.m. Eastern Time ... December 1, 2015 at 11.00 a.m. Eastern Time ... York, NY      Tuesday, December 1, 2015 at ...
Breaking Biology Technology: