Navigation Links
Largest ever genetic study of liver function could point the way to new treatments
Date:10/16/2011

keeping the liver working normally, and towards identifying targets for drugs that can help prevent the liver from functioning abnormally or becoming susceptible to disease."

The researchers identified 42 areas on the genetic code associated with liver function and they then went on to pinpoint 69 associated genes within these areas. Some of the genes are known to play a part in other functions in the body, including inflammation and immunity, and metabolising glucose and carbohydrates.

Professor Jaspal S Kooner, the senior author of the study from the National Heart and Lung Institute at Imperial College London, said: "This massive international research effort provides in-depth new knowledge about the genes regulating the liver. We are particularly excited about the genes whose precise role we don't yet know. Investigating these further should help us to fill in the gaps in our understanding about what happens when the liver ceases to function normally and how we might be able to tackle this."

Professor Paul Elliott, also a senior author of the study, from the School of Public Health at Imperial College London, said: "Liver problems affect a huge number of people and they can have a devastating effect on a person's quality of life. This study represents a vast discovery that opens up multiple new avenues for research."


'/>"/>
Contact: LAURA GALLAGHER
l.gallagher@imperial.ac.uk
0044-207-594-8432
Imperial College London
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mass. Eye and Ear awarded largest NIH grant in hospital’s history
2. Mount Sinai receives $3.4 million for largest study of personalized medicine in the clinical setting
3. Worlds largest sheep an international traveler
4. Media registration opens for Neuroscience 2011, worlds largest meeting on brain science and health
5. Landsat 5 satellite helps emergency managers fight largest fire in Arizona history
6. Caltech researchers build largest biochemical circuit out of small synthetic DNA molecules
7. EUREKA, the largest European network for industrial R&D and innovation, launches E!NNOVEST
8. Scientists discover the largest assembly of whale sharks ever recorded
9. The Pantanal: A book on the ecology of the largest contiguous wetland in the world
10. Newly discovered natural arch in Afghanistan one of worlds largest
11. Energy, security, superconductivity and more at the largest physics meeting of the year
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/11/2014)... are more than 300,000 cases of Lyme disease in the ... to the CDC were concentrated heavily in the Northeast and ... In fact, the disease gets its name from the northeastern ... However, a new article published in the Journal of ... disease Ixodes scapularis , also known as blacklegged ...
(Date:9/11/2014)... known for her work as a high-energy experimental particle ... international consortium of scientists who detected the Higgs boson ... Hadron Collider. , But Bean, a professor of physics ... a long-running passion for engaging the public with science. ... artists and museum educators in the creation of "Quarked," ...
(Date:9/11/2014)... A new study led by the Wildlife Conservation ... where leopards prowl at night, it,s not livestock that,s ... friend. , The study, which looked at scat samples ... that 87 percent of their diet was made up ... most common prey item at 39 percent and domestic ...
Breaking Biology News(10 mins):Physics researcher to advise faith-based office in US Department of State 2Study: Cat bites dog 2
... men die of prostate cancer. It,s Australia,s second worst ... cancer on women. Current therapies for prostate ... the tumour or cutting off the supply of the ... impotence. Growing cells need an essential nutrient, the ...
... of the scientific and technical publishing business of John Wiley ... Society Located in Taipei have signed an agreement to closely ... Chemical Society . The journal will be available online from ... most extensive multidisciplinary collections of online resources, used by 10 ...
... distinct from hematopoietic cells, are an essential component ... for the long-term maintenance of hematopoietic stem cells ... stromal cells regulate the proliferation and differentiation of ... factors and extracellular matrix, and through physical cell-cell ...
Cached Biology News:Starving prostate cancer 2Journal of the Chinese Chemical Society expands international reach with Wiley-VCH 23-D long-term bone marrow culture to analyze stromal cell biological function 2
(Date:9/11/2014)... Awarded annually by Germany’s Design ... internationally recognized quality label for excellent design. METTLER ... coveted Red Dot award in recognition ... Powder Dispenser (HPD). , The Quantos Handheld ... and ease-of-use to applications involving free-flowing powders. Forget ...
(Date:9/11/2014)... WILMINGTON, Del. (PRWEB) September 11, 2014 ... LLC is excited to announce that it has ... including their two wholly owned subsidiaries, Essex ... as distributors of Zemea® USP propanediol in the ... covers the following USA eastern and mid-western states: ...
(Date:9/11/2014)... LONDON , Sept. 11, 2014 /PRNewswire/ ... the charity,s development and commercialisation arm, have reached an ... company in the emerging field of regenerative medicine, ... into clinical trials in subjects with non-small cell ... treatment to enter Cancer Research UK,s Clinical Development ...
(Date:9/11/2014)... The Stem Cell Institute, located in Panama ... cord stem cell therapy on Saturday, September 20, 2014 in ... from 1:00 pm to 4:00 pm. , Stem Cell ... “Umbilical Cord Stem Cell Clinical Trials for MS and Autism: ... of the Stem Cell Institute and Medistem Panama Inc. ...
Breaking Biology Technology:METTLER TOLEDO Handheld Powder Receives Red Dot Award for Product Design 2DuPont Tate & Lyle Bio Products Appoints Skidmore Sales as Distributor for Zemea® USP 2DuPont Tate & Lyle Bio Products Appoints Skidmore Sales as Distributor for Zemea® USP 3Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 2Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 3Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 4Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 5Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 6Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 7Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 8Stem Cell Institute Public Seminar on Adult Stem Cell Therapy Clinical Trials in San Antonio, Texas September 20th, 2014 2Stem Cell Institute Public Seminar on Adult Stem Cell Therapy Clinical Trials in San Antonio, Texas September 20th, 2014 3Stem Cell Institute Public Seminar on Adult Stem Cell Therapy Clinical Trials in San Antonio, Texas September 20th, 2014 4
... in a series of articles on developing start-up companies ... article focused on the tax law implications of employees ... unemployment insurance. , , Madison, Wis. ... test for determining independent contractor status. Although this test ...
... that a CIO's head has to be on a swivel. ... consistent theme during the Fusion 2007 CEO-CIO Symposium , ... directions, and risk management has surpassed security as the paramount ... opening keynote, where John Swainson, chief executive of CA ...
... web-centric business sector continued its crash in 2001, the directors ... their Wisconsin-based business unit. Their decision was only delayed when ... meeting in New York scheduled for that tragic day. , ... Dan Maynard pleaded with board members to keep the division ...
Cached Biology Technology:Early Stage, Step 8: Misclassifying workers brings risk 2Early Stage, Step 8: Misclassifying workers brings risk 3Early Stage, Step 8: Misclassifying workers brings risk 4Early Stage, Step 8: Misclassifying workers brings risk 5Fusion 2007: IT threats make risk management paramount 2Fusion 2007: IT threats make risk management paramount 3Connecture's Maynard finds IT business opportunity in adversity 2Connecture's Maynard finds IT business opportunity in adversity 3Connecture's Maynard finds IT business opportunity in adversity 4Connecture's Maynard finds IT business opportunity in adversity 5Connecture's Maynard finds IT business opportunity in adversity 6
...
...
... derived from the Spodoptera frugiperda Sf21 cell line ... transfections, plaque assays, virus production, and protein expression. ... optimizes recovery of viable cells after thawing. They ... Cell Medium and can also be grown in ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Biology Products: