Navigation Links
Largest-ever database for liver proteins may lead to treatments for hepatitis
Date:11/11/2009

Scientists at a group of 11 research centers in China are reporting for the first time assembly of the largest-ever collection of data about the proteins produced by genes in a single human organ. Their focus was the liver, and their massive database in both protein and transcript levels could become a roadmap for finding possible new biomarkers and treatments for liver disease. Those include hepatitis and liver cancer, which is at epidemic levels in China and affects millions of people worldwide. Part of the China Human Liver Proteome Project, which was officially launched by the Ministry of Science and Technology of China (MOST) and chaired by Fuchu He, the study appears online in ACS' Journal of Proteome Research.

He and colleagues point out that the liver plays many essential roles in the body, such as producing digestive enzymes, hormones, most of the proteins in the blood, storing carbohydrates for use in supplying energy to the muscles, and activates and breaks down drugs. Despite that key role, huge gaps likely exist in scientific knowledge about proteins involved in these activities.

Using 10 tissue samples of healthy liver from volunteers, they identified 6,788 non-redundant proteins in the liver samples, the largest group of proteins ever identified by scientists in any human organ. Half of the proteins have never been seen in the human liver before. One intriguing and unexplained discovery: Many of the new-found proteins appear related to diseases in the nervous system.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Rutgers-Camden developing enzyme function database
2. International collaboration by scientists culminates in novel ion channels database
3. New MegaMatcher Accelerator Boosts Speed for High-Volume Biometric Identification and Database Duplicate Searching
4. Canadian scientist mines drugs database for new diabetes treatment
5. Scientists mine drugs database for new diabetes treatment
6. Soybean database will help breeders engineer better-performing plants
7. Pfizer inks global license to Genomatix Software and databases
8. Database shows effects of acid rain on microorganisms in Adirondack Lakes
9. Lincoln Park Zoo launches first-of-its-kind wildlife reintroduction database
10. Scientists launch first comprehensive database of human oral microbiome
11. Scientists launch human oral microbiome database
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Largest-ever database for liver proteins may lead to treatments for hepatitis
(Date:4/4/2017)... --  EyeLock LLC , a leader of iris-based identity ... and Trademark Office (USPTO) has issued U.S. Patent No. ... iris image with a face image acquired in sequence ... th issued patent. "The issuance ... multi-modal biometric capabilities that have recently come to market ...
(Date:3/30/2017)... -- The research team of The Hong Kong Polytechnic ... by adopting ground breaking 3D fingerprint minutiae recovery and matching technology, ... accuracy for use in identification, crime investigation, immigration control, security of ... ... A research team led by Dr ...
(Date:3/28/2017)... 2017 The report "Video Surveillance ... Servers, Storage Devices), Software (Video Analytics, VMS), and Service ... Forecast to 2022", published by MarketsandMarkets, the market was ... projected to reach USD 75.64 Billion by 2022, at ... base year considered for the study is 2016 and ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Md. (PRWEB) , ... October 11, 2017 , ... ... digital pathology, announced today it will be hosting a Webinar titled, “Pathology is ... Advanced Pathology Associates , on digital pathology adoption best practices and how Proscia ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study ... in frozen and fresh in vitro fertilization (IVF) transfer cycles. The ... IVF success. , After comparing the results from the fresh and frozen transfer ...
(Date:10/10/2017)... , ... October 10, 2017 , ... ... Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of the ... for Excellence in Volunteer Experience from US2020. , US2020’s mission is to change ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... process optimization firm for the life sciences and healthcare industries, announces a presentation ... San Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will ...
Breaking Biology Technology: