Navigation Links
Largest-ever database for liver proteins may lead to treatments for hepatitis
Date:11/11/2009

Scientists at a group of 11 research centers in China are reporting for the first time assembly of the largest-ever collection of data about the proteins produced by genes in a single human organ. Their focus was the liver, and their massive database in both protein and transcript levels could become a roadmap for finding possible new biomarkers and treatments for liver disease. Those include hepatitis and liver cancer, which is at epidemic levels in China and affects millions of people worldwide. Part of the China Human Liver Proteome Project, which was officially launched by the Ministry of Science and Technology of China (MOST) and chaired by Fuchu He, the study appears online in ACS' Journal of Proteome Research.

He and colleagues point out that the liver plays many essential roles in the body, such as producing digestive enzymes, hormones, most of the proteins in the blood, storing carbohydrates for use in supplying energy to the muscles, and activates and breaks down drugs. Despite that key role, huge gaps likely exist in scientific knowledge about proteins involved in these activities.

Using 10 tissue samples of healthy liver from volunteers, they identified 6,788 non-redundant proteins in the liver samples, the largest group of proteins ever identified by scientists in any human organ. Half of the proteins have never been seen in the human liver before. One intriguing and unexplained discovery: Many of the new-found proteins appear related to diseases in the nervous system.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Rutgers-Camden developing enzyme function database
2. International collaboration by scientists culminates in novel ion channels database
3. New MegaMatcher Accelerator Boosts Speed for High-Volume Biometric Identification and Database Duplicate Searching
4. Canadian scientist mines drugs database for new diabetes treatment
5. Scientists mine drugs database for new diabetes treatment
6. Soybean database will help breeders engineer better-performing plants
7. Pfizer inks global license to Genomatix Software and databases
8. Database shows effects of acid rain on microorganisms in Adirondack Lakes
9. Lincoln Park Zoo launches first-of-its-kind wildlife reintroduction database
10. Scientists launch first comprehensive database of human oral microbiome
11. Scientists launch human oral microbiome database
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Largest-ever database for liver proteins may lead to treatments for hepatitis
(Date:5/16/2016)... YORK , May 16, 2016   EyeLock ... solutions, today announced the opening of an IoT Center ... to strengthen and expand the development of embedded iris ... an unprecedented level of convenience and security with unmatched ... authenticate one,s identity aside from DNA. EyeLock,s platform uses ...
(Date:5/9/2016)... UAE, May 9, 2016 Elevay ... comes to expanding freedom for high net worth professionals ... in today,s globally connected world, there is still no ... could ever duplicate sealing your deal with a firm ... passports by taking advantage of citizenship via investment programs ...
(Date:4/28/2016)... and BANGALORE, India , April 28, 2016 ... a product subsidiary of Infosys (NYSE: INFY ), ... a global partnership that will provide end customers ... mobile banking and payment services.      (Logo: ... innovation area for financial services, but it also plays a ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)...  The Biodesign Challenge (BDC), a university competition that ... living systems and biotechnology, announced its winning teams at ... New York City . The teams, ... at MoMA,s Celeste Bartos Theater during the daylong summit. ... curator of architecture and design, and Suzanne Lee ...
(Date:6/23/2016)... June 23, 2016 Apellis Pharmaceuticals, Inc. ... clinical trials of its complement C3 inhibitor, APL-2. ... multiple ascending dose studies designed to assess the ... subcutaneous injection in healthy adult volunteers. ... as a single dose (ranging from 45 to ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... and technical consulting, provides a free webinar on Performing Quality Investigations: ... 2016 at 12pm CT at no charge. , Incomplete investigations are still a ...
Breaking Biology Technology: