Navigation Links
Large-scale study focuses on heavy smokers
Date:8/25/2014

It is a fact that smoking is harmful and associated with deadly diseases such as cancer and cardiovascular disease. Researchers also know that smokers die earlier than non-smokers. But a study that sheds light on the direct causal relationship between smoking and mortality by investigating genes has never been published before:

We have studied 55,568 individuals, including 32,823 smokers who we followed for ten years. 3,430 died during this period. The epidemiological studies were supported by genetic analyses, and the conclusion is clear. Smoking is associated with premature death, and heavy smokers have a 75 percent higher risk of dying than never-smokers of the same age. This may not come as a surprise, but it is actually the first time that this type of study which presents a direct causal relationship between smoking and mortality has been carried out, says Professor and chief physician Brge Nordestgaard from the University of Copenhagen and Copenhagen University Hospital.

Smoking gene increases tobacco consumption

The researchers have also studied a special gene variant that impacts heavy smoking: The smoking gene has no influence on whether you start or quit smoking. But if you do smoke, the gene will make you smoke more. People who have inherited the gene variant from both their parents smoke 20 percent more than those without the special gene variant.

There is a lot to suggest that you can be genetically predisposed to heavy smoking. Smokers carrying a special genetic mutation have a higher tobacco consumption and they are more affected by smoking, e.g. by having higher blood nicotine levels. They quite simply smoke more convincingly which is, of course, very harmful for their health and they have a 14 percent higher risk of dying before other smokers, says Brge Nordestgaard.

The study is based on the Copenhagen General Population Study and was carried out together with, amongst others, Line Rode, MD, PhD, at Copenhagen University Hospital.

Read more in the International Journal of Epidemiology.


'/>"/>

Contact: Børge Nordestgaard
Boerge.Nordestgaard@regionh.dk
45-30-28-72-63
University of Copenhagen The Faculty of Health and Medical Sciences
Source:Eurekalert

Related biology news :

1. Scientists provide first large-scale estimate of reef shark losses in the Pacific Ocean
2. Aware Provides Biometrics Software and Services for Three Large-Scale Border Management Systems
3. Bay Area PV Consortium announces $7.5 million in grants to lower the cost of large-scale solar
4. Launch of the EU large-scale integrating project BlueGenics to combat osteoporosis
5. Can algae-derived oils support large-scale, low-cost biofuels production?
6. Medical societies to launch large-scale study on vein filter use
7. The large-scale EU project EU BON: Towards integration with its global counterpart GEO BON
8. Genes behind obesity mapped in large-scale study
9. Large-scale biodiversity is vital to maintain ecosystem health
10. Rheumatoid arthritis research shows the potential of large-scale genetic studies for drug discovery
11. Major meeting to propose large-scale solutions to landscape challenges in Africa
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... -- Veratad Technologies, LLC ( www.veratad.com ), an innovative and ... solutions, announced today they will participate as a sponsor ... May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions of ... digital world, defining identity is critical to nearly every ...
(Date:4/24/2017)... WASHINGTON , April 24, 2017 ... counsel and partner with  Identity Strategy Partners, LLP ... "With or without President Trump,s March 6, ... Foreign Terrorist Entry , refugee vetting can be instilled ... refugee resettlement. (Right now, all refugee applications are ...
(Date:4/17/2017)... 17, 2017 NXT-ID, Inc. (NASDAQ: NXTD ... filing of its 2016 Annual Report on Form 10-K on Thursday ... ... available in the Investor Relations section of the Company,s website at ... website at http://www.sec.gov . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... A new study published in ... and fresh in vitro fertilization (IVF) transfer cycles. The multi-center matched ... , After comparing the results from the fresh and frozen transfer cohorts, the ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... FirstHand program has won a US2020 STEM Mentoring Award. Representatives of the FirstHand ... Excellence in Volunteer Experience from US2020. , US2020’s mission is to change the ...
(Date:10/10/2017)... SANTA BARBARA, CALIFORNIA (PRWEB) , ... October 10, ... ... risk management, technological innovation and business process optimization firm for the life sciences ... the BoxWorks conference in San Francisco. , The presentation, “Automating GxP ...
(Date:10/9/2017)... Charlotte, N.C. (PRWEB) , ... October 09, 2017 , ... ... Purple announced Dr. Christopher Stubbs, a professor in Harvard University’s Departments of Physics and ... Dr. Stubbs was a member of the winning team for the 2015 Breakthrough Prize ...
Breaking Biology Technology: