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Large human study links phthalates, BPA and thyroid hormone levels
Date:7/11/2011

population being exposed at this level you'd see many more thyroid related effects in people."

Researchers looked at another phthalate called DBP but overall, didn't find a significant relationship between exposure and thyroid measures. DBP is also a plasticizer, and is also used in solvents and personal care products.

Thyroid hormones play an important role in many body functions, from reproduction to metabolism and energy balance.

While the study focused primarily on adults, these findings underscore the need for more research on adults, pregnant women, and children, Meeker said, because fetal and child development may be particularly vulnerable to disruptions in thyroid hormone levels associated with exposure to environmental chemicals.

Meeker pointed out that the study had limitations. Since urine and serum samples were collected at a single point in time, researchers couldn't conclude a cause-and-effect relationship; it would be better to follow people over time and collect several samples, especially since these chemicals metabolize quickly and one snapshot may not represent the true chemical exposure.

The group has several ongoing studies on the potential impacts of phthalate and BPA exposure on pregnancy outcomes and child development.


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Contact: Laura Bailey
baileylm@umich.edu
734-764-1552
University of Michigan
Source:Eurekalert

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