Navigation Links
Large human study links phthalates, BPA and thyroid hormone levels
Date:7/11/2011

ANN ARBOR, Mich.---A link between chemicals called phthalates and thyroid hormone levels was confirmed by the University of Michigan in the first large-scale and nationally representative study of phthalates and BPA in relation to thyroid function in humans.

The U-M School of Public Health study also reported suggestive findings consistent with a previously reported link between a chemical called bisphenol-A and thyroid hormone levels. BPA is best known for its use in certain plastic water bottles and in the linings of canned foods.

Researchers used publicly available data from the U.S. National Health and Nutrition Examination Survey to compare urine metabolites and serum thyroid measures from 1,346 adults and 329 adolescents. Generally speaking, greater concentrations of urinary phthalate metabolites and BPA were associated with greater impacts on serum thyroid measures, said John Meeker, assistant professor at U-M SPH and lead study author.

Specifically, researchers found an inverse relationship between urinary markers of exposure and thyroid hormone levels, meaning as urinary metabolite concentrations increased, serum levels of certain thyroid hormone levels decreased.

Phthalates and BPA are chemical compounds that appear in solvents, plasticizers and common household products. These latest results were consistent with findings from previous smaller studies by Meeker and others that suggested the relationship.

The current study showed the strongest relationship between thyroid disruption and DEHP, a phthalate commonly used as a plasticizer. Research has shown that the primary exposure to DEHP is through diet. Urine samples in the highest 20 percent of exposure to DEHP were associated with as much as a 10 percent decrease in certain thyroid hormones compared to urine samples at the lowest 20 percent of exposure.

"This seems like a subtle difference," Meeker said, "but if you think about the entire
'/>"/>

Contact: Laura Bailey
baileylm@umich.edu
734-764-1552
University of Michigan
Source:Eurekalert

Page: 1 2

Related biology news :

1. Large numbers of birth defects seen near mountaintop mining operations
2. College scientist cites enlarged skeletal muscles as reason birds exist
3. Landsat 5 satellite helps emergency managers fight largest fire in Arizona history
4. Major flooding on the Mississippi River likely to cause large Gulf of Mexico dead zone
5. Glaciations may have larger influence on biodiversity tan current climate
6. Glaciations may have larger influence on biodiversity than current climate
7. Caltech researchers build largest biochemical circuit out of small synthetic DNA molecules
8. EUREKA, the largest European network for industrial R&D and innovation, launches E!NNOVEST
9. Scientists discover the largest assembly of whale sharks ever recorded
10. The Pantanal: A book on the ecology of the largest contiguous wetland in the world
11. Undergraduate institutions should play larger research role
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... examples of complex systems. Their infrastructure equipment requires ... cooling, transport to supply fuel, and ICT systems ... network chain is interconnected with a wider network ... of UK-based scientists has studied various aspects of ... been published in EPJ B by Gaihua Fu ...
(Date:8/28/2014)... This news release is available in German . ... electronic products are now built with the help of sophisticated ... are fixed, are an important part of these assembly lines. ... are attached in various work stages arranged in a precise ... the end of the line. , The creation of such ...
(Date:8/28/2014)... Protected areas conserve biodiversity and more action is needed ... areas, researchers say. , Published in PLOS ONE ... University of Exeter, used meta-analysis - combining results from ... years of research into these areas, to determine whether ... School of Biological Sciences, said protecting an area from ...
Breaking Biology News(10 mins):Inter-dependent networks stress test 2Nanoscale assembly line 2Nanoscale assembly line 3Protected areas proven to protect biodiversity 2
... Irvine, Calif., July 12, 2011 UC Irvine researchers ... customized therapies for virulent flu strains that resist current ... Amaro and Robin Bush created a method to predict ... promoting viral replication can be identified as these proteins ...
... The National Heart, Lung and Blood Institute, one of ... at the Johns Hopkins University School of Medicine each ... establish two Programs of Excellence in Glycosciences. Gerald Hart, ... professor of pharmacology and molecular sciences, will lead these ...
... Beach, FL. New research findings to be presented ... Study of Ingestive Behavior (SSIB), the foremost society for research ... ghrelin, a natural gut hormone that stimulates feeding, also modulates ... dopamine levels within the striatum, a critical component of the ...
Cached Biology News:UCI study points to new means of overcoming antiviral resistance in influenza 2Johns Hopkins researchers awarded $32 million 2
(Date:8/28/2014)... Best Sanitizers, Inc., a leader in hand ... is asking industry professionals to prepare for fall harvest ... soap they’re currently using to the Best Sanitizers’ ... hygiene is critical to fighting cross-contamination and the spread ... criteria are identified to evaluate the effectiveness of an ...
(Date:8/28/2014)... , Aug. 28, 2014 /PRNewswire/ ... new market research report is ... Whole Exome Sequencing Market ... Preparation, Target Enrichment), by Services ... Synthesis), by Application (Cancer, Monogenic ...
(Date:8/28/2014)... PARK, Calif. , Aug. 28, 2014 /PRNewswire/ ... focused on developing novel mid- to late-stage cardiovascular ... $7.0 million in its first round of financing. ... Biomedical Investments and Hercules Bioventures with participation from ... entrepreneur and pharmaceutical executive, Dr. Larry Hsu ...
(Date:8/28/2014)... PrimeSource Building Products, Inc., a ... SoundConnect to support their communication needs with ... web conferencing platform GlobalMeet powered by SoundConnect. The ... SoundConnect delivers award winning “results driven” business ... will be utilizing GlobalMeet powered by SoundConnect ...
Breaking Biology Technology:Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 2Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 3Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 4Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 5Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 6Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 7Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 8Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 9Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 10Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 11Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 12Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 13Armetheon Completes $7.0 Million Series A Financing 2Armetheon Completes $7.0 Million Series A Financing 3PrimeSource Chooses SoundConnect as Collaboration Provider 2
... PALO ALTO, Calif., Feb. 7 Avicena Group, ... that,develops central nervous system therapeutics for neurodegenerative,disorders, announced ... Nivaggioli, Ph.D., will present an overview of the ... BIO CEO & Investor,Conference to be held February ...
... Feb. 7 Logical Therapeutics, Inc., a,biotechnology company ... associated with poorly controlled inflammation, announced today,that its ... presented with the,Distinguished Investigator Award from the American ... Care Congress of the Society of Critical,Care Medicine ...
... Home-Based Device Market Featuring Diode Laser ... Technology for Hair ... in,light-based therapeutic beauty devices, today announced over-the-counter,(OTC) clearance from the ... laser hair removal device designed for at-home,use. The TRIA is ...
Cached Biology Technology:Avicena Group to Present at 10th Annual BIO CEO & Investor Conference 2Avicena Group to Present at 10th Annual BIO CEO & Investor Conference 3Logical Therapeutics Co-Founder and CEO Honored with a Distinguished Investigator Award from the American College of Critical Care Medicine 2TRIA At-Home Laser Hair Removal Device Cleared by FDA 2
...
Anti-Indolamine (Indoleamine) 2,3-dioxygenase Immunogen: Recombinant human IDO. Available Date: 38454...
Anti-Ephrin B1 Host: rabbit polyclonal Species Reactivity: human Applications: WB Storage: 4C...
Human Regulatory T cell Staining Kit #2 (w/ APC Foxp3 PCH101, FITC CD4, PE CD25)...
Biology Products: