Navigation Links
Large amounts of folic acid shown to promote growth of breast cancer in rats
Date:1/21/2014

TORONTO, Jan. 21, 2014---Folic acid supplements at levels consumed by breast cancer patients and survivors in North America promoted the growth of existing breast cancer in rats, new research found.

The role of folate, a B vitamin, and its synthetic form, folic acid, in the development and progression of breast cancer is highly controversial. Although some studies have found it may offer protection against breast cancer, recent studies have suggested that taking high amounts of folic acid may increase the risk of developing breast cancer.

Dr. Young-In Kim, a physician and researcher at St. Michael's Hospital, said his lab has shown for the first time that folic acid supplements in doses 2.5 to five times the daily requirement "significantly promotes" the growth of existing pre-cancerous or cancerous cells in the mammary glands of rats. His research was published today in the online journal PLOS ONE.

"This is a critically important issue because breast cancer patients and survivors in North America are exposed to high levels of folic acid through folic acid fortification in food and widespread use of vitamin supplements after a cancer diagnosis," Dr. Kim said. "Cancer patients and survivors in North America have a high prevalence of multivitamin and supplement use, with breast cancer patients and survivors having the highest prevalence."

The amount of folic acid consumed in North America has increased dramatically in the past 15 years. Women are routinely advised to take folic acid supplements before becoming pregnant and while pregnant to prevent neural tube birth defects such as spina bifida. Since 1998, the Canadian and U.S. governments have required food manufacturers to add folic acid to white flour, enriched pasta and cornmeal products as a way of ensuring women receive enough of the B vitamin. In addition, up to 30 to 40 per cent of North Americans take folic acid supplements for possible but as yet unproven health benefits.

Dr. Kim is also a professor of medicine at the University of Toronto. This research was funded in part by the Canadian Institutes of Health Research.


'/>"/>

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital
Source:Eurekalert  

Related biology news :

1. Study shows large carnivore numbers and range declining worldwide
2. Loss of large carnivores poses global conservation problem
3. Big data: A method for obtaining large, phylogenomic data sets
4. Montana State University research on algal biofuels keys larger study
5. Rheumatoid arthritis research shows the potential of large-scale genetic studies for drug discovery
6. Researchers create largest evolutionary timetree of land plants to investigate traits that permit survival in cold climates
7. Thousands of new particles in workplaces despite large knowledge gap
8. Large study shows pollution impact on coral reefs -- and offers solution
9. Archaeologists discover largest, oldest wine cellar in Near East
10. Large dishes increase how much cereal kids request, eat, and waste
11. New technique controls dimensions of gold nanorods while manufacturing on a large scale
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Large amounts of folic acid shown to promote growth of breast cancer in rats
(Date:3/9/2016)... , March 9, 2016 This BCC ... future states of the RNA Sequencing (RNA Seq) market ... such as instruments, tools and reagents, data analysis, and ... various segments of the RNA-Sequencing market such as RNA-Sequencing ... Identify the main factors affecting each segment and forecast ...
(Date:3/9/2016)... GARDENS, Fla. , March 9, 2016 /PRNewswire/ ... management authentication and enrollment solutions, today announced the ... DigitalPersona ® Altus multi-factor authentication platform. ... and InfoSec managers to step-up security where it,s ... Washington, DC . ...
(Date:3/3/2016)...  FlexTech, a SEMI Strategic Association Partner, awarded five ... Development, Leadership in Education, and, in a category new ... year of the FLEXI Awards and the winners ... past years . Judging was done on a ... criteria, by a panel of non-affiliated, independent, industry experts. ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... RESEARCH TRIANGLE PARK, N.C. , April ... UTHR ) announced today that Martine Rothblatt , ... will provide an overview and update on the company,s ... Health Care Conference. The presentation will take ... Eastern Time, and can be accessed via a live ...
(Date:4/27/2016)... ... 2016 , ... A compact PET scanner called NuPETâ„¢ has ... Resonance Imaging) in existing third-party MRI systems. PET and MRI are complementary imaging ... Simultaneous PET/MRI imaging offers a solution to many challenges that face researchers who ...
(Date:4/27/2016)... ReportsnReports.com adds 2016 global ... on US, EU, China ... healthcare business intelligence collection of its growing online ... on the Flow Cytometry market spread across 153 ... tables and figures is now available at ...
(Date:4/26/2016)... ... April 26, 2016 , ... Heidelberg Instruments, a leader in ... for its Volume Pattern Generator (VPG) line of lithography systems. The breakthrough VPG+ ... well as a solution for mid volume direct write lithography applications. It ...
Breaking Biology Technology: