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Landon Foundation-AACR INNOVATOR Awards
Date:4/11/2008

ese problems. Specifically, Maley will apply funds from his AACR INNOVATOR grant to the development of models of Barretts esophagus, a human pre-malignant neoplasm that can lead to esophageal cancer. His analysis of the genetics and molecular biology of Barretts esophagus may serve as a basis for predicting which patients are likely to progress to full-blown esophageal cancer. Maley is working to translate these findings to the development of a method for identifying and assessing biomarkers for cancer prevention. By detecting genetic diversity in tumor cells, his analysis has the potential to identify which tumors are likely to progress and whether they may be sensitive to preventive therapies. This approach offers the possibility of having a practical tool that could benefit clinical practice as well as development of future preventive therapies.

The Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research is presented to a team of experts in genetics, thoracic oncology, geology and pathology working in the United States and Turkey. The award supports highly meritorious research being conducted collaboratively by investigators in different countries around the world, and aims to promote international cancer research collaboration as an effective means to accelerate progress against cancer by providing the necessary support to sustain and enhance such collaborations. Team members include: lead researcher Michele Carbone, M.D., Ph.D., and Haining Yang, Ph.D., University of Hawaii; Nancy Cox, Ph.D., and Ian Steele, Ph.D., University of Chicago; Harvey Pass, M.D., NYU School of Medicine and Clinical Cancer Center; Joseph Testa, Ph.D., Fox Chase Cancer Center; Y. Izzetin Baris, M.D., University of Hacettepe in Ankara, Turkey; A. Umran Dogan, Ph.D., University of Iowa; and Salih Emri, M.D., and Murat Tuncer, M.D., Hacettepe University School of Medicine in Ankara, Turkey.

International collaboratio
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Contact: Jennifer Ryan
jennifer.ryan@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert

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