Navigation Links
Landenberger Foundation awards grant to Scripps Florida scientist to study HIV

A scientist on the Florida campus of The Scripps Research Institute has received funding from the Philadelphia-based Margaret Q. Landenberger Research Foundation.

Susana T. Valente, an assistant professor in the Department of Infectology, received a two-year $240,000 grant to expand her study of the many genes and protein products that HIV, the virus that causes AIDS, uses to live inside human cells. These unique molecular interactions between retrovirus and host cell are potential therapeutic targets that might be exploited to disarm the virus without endangering the viability of the cell.

"I'm honored to receive this award from the Landenberger Foundation," Valente said. "This award will help me continue to focus on understanding how viruses like HIV use the machinery of host cells to replicate, as well as to explore some novel ways to prevent that from happening. The foundation has been very supportive of the work of Scripps Florida scientists, and I'm pleased that they selected our laboratory for this latest award."

In addition to identifying the molecular interactions between virus and host, Valente's research has focused on mammalian genes that have evolved within cells to block replication.

In a recently published study in the journal Molecular Cell, Valente and colleagues screened various biological libraries for genes or gene fragments to identify those host factors critical to HIV that might interfere with the virus's replication. The scientists found a specific host factor with the power to block HIV replication by reducing the processing of messenger RNA; mRNA, which is synthesized from DNA during transcription, carries the DNA code into the cytoplasm of the cell where it becomes a template for protein synthesis. Without mRNA, the virus cannot successfully reproduce.

Valente is the fifth Scripps Florida scientist to receive an award from the foundation in the last four years, an exceptional showing in a highly competitive environment. In the future, all awards will likely be restricted to a single grant per year per institution, according to a Landenberger spokesman.

In 2007, Nagi Ayad, an assistant professor in the Department of Cancer Biology, and Paul Kenney, an associate professor in the Department of Molecular Therapeutics, received a three-year grant of $350,000 and a single year grant of $65,000 respectively. In 2008, Michael Conkright, also an assistant professor in the Department of Cancer Biology, received a $150,000 grant. Earlier this year, Donny Strosberg, a professor in the Department of Infectology, was awarded $300,000 over three years.

The Landenberger Foundation also approved a 2010 award of $25,000 to Scripps Florida for a special conference to help other small foundations that specialize in supporting biomedical research to develop greater expertise in their review and analysis of scientific grant requests.


Contact: Mika Ono
Scripps Research Institute

Related biology news :

1. Jefferson researcher awarded Landenberger Foundation grant for ALS research
2. Entomological Foundation names 2010 award winners
3. American Migraine Foundation launches new podcast series
4. UofL researcher receives grant from the National Science Foundation
5. Stem cell, artificial liver research receives Coulter Foundation funding at NJIT
6. The Samuel Waxman Cancer Research Foundation awards $1.54 million in research grants for 2010-2011
7. Damon Runyon Cancer Research Foundation awards prestigious fellowships to 18 top young scientists
8. 12 women scientists announced as winners of Elsevier Foundation TWOWS Awards
9. NYSCF receives $27 million grant from Robertson Foundation to promote stem cell research
10. International Osteoporosis Foundation honors longtime associate
11. More Than 100 Global and U.S. Municipal Leaders Join Mayor Daley, Business, Civic, Academic and Foundation Leaders at 2010 Richard J. Daley Global Cities Forum
Post Your Comments:
(Date:10/29/2015)... ANN ARBOR, Mich. , Oct. 29, 2015 ... with Eurofins Genomics for U.S. distribution of its ... DNA-seq kit and Rubicon,s new ThruPLEX Plasma-seq ... DNA to enable the preparation of NGS libraries ... in plasma for diagnostic and prognostic applications in ...
(Date:10/27/2015)... 2015 In the present market scenario, security ... various industry verticals such as banking, healthcare, defense, electronic ... demand for secure & simplified access control and growing ... hacking of bank accounts, misuse of users, , and ... PC,s, laptops, and smartphones are expected to provide potential ...
(Date:10/26/2015)... LAS VEGAS , Oct. 26, 2015 ... an innovator in modern authentication and a founding member ... launch of its latest version of the Nok Nok™ ... to use standards-based authentication that supports existing and emerging ... Suite is ideal for organizations deploying customer-facing applications that ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... , Nov. 24, 2015 Cepheid (NASDAQ: ... be speaking at the following conference, and invited investors ... York, NY      Tuesday, December 1, 2015 at ... York, NY      Tuesday, December 1, 2015 at ... Healthcare Conference, New York, NY ...
(Date:11/24/2015)... 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS) (TSX: AEZ) ... of the Toronto Stock Exchange, confirms that as of ... corporate developments that would cause the recent movements in ... --> About Aeterna Zentaris Inc. ... Aeterna Zentaris is a specialty biopharmaceutical company engaged ...
(Date:11/24/2015)... SHPG ) announced today that Jeff Poulton , ... Annual Healthcare Conference in New York City ... (1:30 p.m. GMT). --> SHPG ) announced today that ... Piper Jaffray 27 th Annual Healthcare Conference in ... at 8:30 a.m. EST (1:30 p.m. GMT). --> Shire ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... ... and the environment are paramount. Insertion points for in-line sensors can represent a ... developed the InTrac 781/784 series of retractable sensor housings , which are ...
Breaking Biology Technology: