Navigation Links
Landenberger Foundation awards grant to Scripps Florida scientist to study HIV
Date:10/26/2010

A scientist on the Florida campus of The Scripps Research Institute has received funding from the Philadelphia-based Margaret Q. Landenberger Research Foundation.

Susana T. Valente, an assistant professor in the Department of Infectology, received a two-year $240,000 grant to expand her study of the many genes and protein products that HIV, the virus that causes AIDS, uses to live inside human cells. These unique molecular interactions between retrovirus and host cell are potential therapeutic targets that might be exploited to disarm the virus without endangering the viability of the cell.

"I'm honored to receive this award from the Landenberger Foundation," Valente said. "This award will help me continue to focus on understanding how viruses like HIV use the machinery of host cells to replicate, as well as to explore some novel ways to prevent that from happening. The foundation has been very supportive of the work of Scripps Florida scientists, and I'm pleased that they selected our laboratory for this latest award."

In addition to identifying the molecular interactions between virus and host, Valente's research has focused on mammalian genes that have evolved within cells to block replication.

In a recently published study in the journal Molecular Cell, Valente and colleagues screened various biological libraries for genes or gene fragments to identify those host factors critical to HIV that might interfere with the virus's replication. The scientists found a specific host factor with the power to block HIV replication by reducing the processing of messenger RNA; mRNA, which is synthesized from DNA during transcription, carries the DNA code into the cytoplasm of the cell where it becomes a template for protein synthesis. Without mRNA, the virus cannot successfully reproduce.

Valente is the fifth Scripps Florida scientist to receive an award from the foundation in the last four years, an exceptional showing in a highly competitive environment. In the future, all awards will likely be restricted to a single grant per year per institution, according to a Landenberger spokesman.

In 2007, Nagi Ayad, an assistant professor in the Department of Cancer Biology, and Paul Kenney, an associate professor in the Department of Molecular Therapeutics, received a three-year grant of $350,000 and a single year grant of $65,000 respectively. In 2008, Michael Conkright, also an assistant professor in the Department of Cancer Biology, received a $150,000 grant. Earlier this year, Donny Strosberg, a professor in the Department of Infectology, was awarded $300,000 over three years.

The Landenberger Foundation also approved a 2010 award of $25,000 to Scripps Florida for a special conference to help other small foundations that specialize in supporting biomedical research to develop greater expertise in their review and analysis of scientific grant requests.


'/>"/>

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert

Related biology news :

1. Jefferson researcher awarded Landenberger Foundation grant for ALS research
2. Entomological Foundation names 2010 award winners
3. American Migraine Foundation launches new podcast series
4. UofL researcher receives grant from the National Science Foundation
5. Stem cell, artificial liver research receives Coulter Foundation funding at NJIT
6. The Samuel Waxman Cancer Research Foundation awards $1.54 million in research grants for 2010-2011
7. Damon Runyon Cancer Research Foundation awards prestigious fellowships to 18 top young scientists
8. 12 women scientists announced as winners of Elsevier Foundation TWOWS Awards
9. NYSCF receives $27 million grant from Robertson Foundation to promote stem cell research
10. International Osteoporosis Foundation honors longtime associate
11. More Than 100 Global and U.S. Municipal Leaders Join Mayor Daley, Business, Civic, Academic and Foundation Leaders at 2010 Richard J. Daley Global Cities Forum
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... Perimeter Surveillance & Detection Systems, Biometrics & ... & Other Service  The latest report from ... of the global Border Security market . Visiongain ... billion in 2016. Now: In November 2015 ... and hardware technologies for advanced video surveillance. ...
(Date:5/24/2016)... 24, 2016 Ampronix facilitates superior patient care by providing unparalleled technology to ... display is the latest premium product recently added to the range of products distributed ... ... ... Imaging- LCD Medical Display- Ampronix News ...
(Date:5/16/2016)... 16, 2016   EyeLock LLC , a market ... opening of an IoT Center of Excellence in ... the development of embedded iris biometric applications. ... convenience and security with unmatched biometric accuracy, making it ... from DNA. EyeLock,s platform uses video technology to deliver ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... HOUSTON , June 23, 2016 ... agreement with the Cy-Fair Sports Association to serve ... of the agreement, Houston Methodist Willowbrook will provide ... education and connectivity with association coaches, volunteers, athletes ... partner with the Cy-Fair Sports Association and to ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
Breaking Biology Technology: