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Laminopathies: Key components in the disease mechanism identified
Date:5/7/2013

s are critical for muscle function, this finding explains, why laminopathies affect mainly this tissue type. It also gives a mechanistic link between altered nuclear envelope structure and gene expression.

This study will give a glimmer of hope to the patients suffering from laminopathies, by identifying key components that underlie the disease mechanism. Restoring MKL1 activity in laminopathies might be a productive intervention mechanism for these devastating diseases.


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Contact: Maria Vartiainen
maria.vartiainen@helsinki.fi
358-919-159-419
University of Helsinki
Source:Eurekalert

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