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Lake sturgeon have genes from parasite, signs of human STD
Date:5/11/2010

WEST LAFAYETTE, Ind. - While trying to find a DNA-based test to determine the sex of lake sturgeon, Purdue University researchers found that the sturgeon genome contains trematode genes that didn't originally belong to it and may harbor a protozoan parasite that causes a sexually transmitted disease in humans.

Genetics professor Andrew DeWoody and postdoctoral associate Matthew C. Hale found the parasite and pathogen genes while analyzing DNA from the gonads of lake sturgeon, a species that is on the decline because of overfishing and pollution of its habitats. The only way to determine a lake sturgeon's sex currently is to examine its internal sexual organs.

DeWoody said about 15 genes found in the lake sturgeon came from Schistosoma, a parasitic worm. Lateral gene transfer from one organism to another is rare, especially in multicellular animals, he said, but could be part of some evolutionary process for the sturgeon.

"Organisms may accept some new genes from other species because the new genes can serve as raw material for evolution," said DeWoody, whose findings were reported in the early online version of the journal Genetica. "The genome may be more fluid than we usually think."

Hale said genes often work in combination, and new genes may one day become involved with other genes to help the lake sturgeon create new traits needed to adapt to changes in its environment.

"It isn't necessarily a bad thing for the sturgeon. It probably doesn't have a cost," Hale said. "It's either neutral or has a benefit or it wouldn't be there."

While lateral gene transfer from a trematode worm could ultimately benefit the lake sturgeon, evidence of the Trichomonas pathogen is more likely to have a negative effect. According to the Centers for Disease Control and Prevention, a human version of this pathogen causes Trichomoniasis, a common sexually transmitted disease that mostly affects women and can cause pregnant wo
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Contact: Brian Wallheimer
bwallhei@purdue.edu
765-496-2050
Purdue University
Source:Eurekalert  

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