Navigation Links
Lab experiments question effectiveness of green coffee bean weight-loss supplements
Date:6/12/2013

A major ingredient in those green coffee bean dietary supplements often touted as "miracle" weight-loss products doesn't prevent weight gain in obese laboratory mice fed a high-fat diet when given at higher doses. That's the conclusion of a first-of-its-kind study published in ACS' Journal of Agricultural and Food Chemistry. It also linked the ingredient to an unhealthy build-up of fat in the liver.

Vance Matthews, Kevin Croft and their team note that coffee is rich in healthful, natural, plant-based polyphenol substances. They cite evidence from past studies that coffee drinkers have a lower risk of obesity, high blood pressure, type 2 diabetes and other disorders collectively termed the "metabolic syndrome." Chlorogenic acid (CGA), one coffee polyphenol, is the main ingredient in scores of dietary supplements promoted as weight-loss products. Much research has been done on mixtures of coffee polyphenols. Until now, however, scientists have not checked the effects of higher doses of CGA alone on obesity and other symptoms of the metabolic syndrome. Matthews' team decided to do that, using special laboratory mice that are stand-ins for humans in such tests.

They report that mice on a high-fat diet and mice on a high-fat diet plus CGA gained the same amount of weight. The CGA mice, however, were more likely to develop disorders that often lead to type 2 diabetes. They also accumulated fat inside the cells in their livers. "This study suggests that higher doses of CGA supplementation in a high-fat diet does not protect against features of the metabolic syndrome in diet-induced obese mice," they say.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Odd experiments by Americas first physiologist shed light on digestion
2. New cutting-edge cell research will lead to safer medical experiments on humans
3. Experiments may understate plant responses to climate
4. To germinate, or not to germinate, that is the question
5. Reliability of neuroscience research questioned
6. Researchers question evaluation methods for protected areas in the Amazon
7. After the Genome tackles tough questions about medicine, miracles and morality
8. Study questions the role of kinship in mass strandings of pilot whales
9. Yeast we can! New report answers questions on microbiology and beer
10. New Geology study raises questions about long-held theories of human evolution
11. Questions about biosafety? Ask a biosafety expert
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
(Date:4/5/2017)... 5, 2017  The Allen Institute for Cell Science ... a one-of-a-kind portal and dynamic digital window into the ... the first application of deep learning to create predictive ... lines and a growing suite of powerful tools. The ... and future publicly available resources created and shared by ...
(Date:3/30/2017)... ANGELES , March 30, 2017  On April ... Hack the Genome hackathon at Microsoft,s ... exciting two-day competition will focus on developing health and ... Hack the Genome is the ... been tremendous. The world,s largest companies in the genomics, ...
Breaking Biology News(10 mins):
(Date:7/24/2017)... ... July 24, 2017 , ... ... Soulstring, today announced that the stock market news outlet had initiated coverage ... diagnostic testing that screens and identifies exposure, progression and risk analysis from ...
(Date:7/20/2017)... ... ... VIC Technology Venture Development™ (VIC™), is pleased to announce that ... continues to strengthen and diversify VIC’s board. , "We are excited to have Jamie ... accomplished business executive with a broad range of experience directly relevant to VIC as ...
(Date:7/18/2017)... ... July 18, 2017 , ... Nanomedical Diagnostics, ... development, announces the launch of a new NTA biosensor chip for use with ... study the kinetics of polyhistidine-tagged (His-tagged) molecules quickly and reliably. , “Recombinant ...
(Date:7/18/2017)... DC (PRWEB) , ... July 18, 2017 , ... ... the Allotrope Framework, and has released the first phase of the Allotrope Framework ... World’s Best Practices Awards were created to “not only elevate the critical role ...
Breaking Biology Technology: