Navigation Links
La Jolla Institute validates Type 1 diabetes computer model's predictive success through lab testing
Date:12/8/2010

SAN DIEGO (December 9, 2010) A La Jolla Institute team, led by leading type 1 diabetes researcher Matthias von Herrath, M.D., has demonstrated the effectiveness of a recently developed computer model in predicting key information about nasal insulin treatment regimens in type 1 (juvenile) diabetes. Development of the software, the Type 1 Diabetes PhysioLab Platform, was funded through the peer-reviewed grant program of the American Diabetes Association.

The findings, which also showed the platform's ability to predict critical type 1 diabetes molecular "biomarkers," were published in the December issue of the scientific journal Diabetes, and further validate the importance of the new model as a valuable research tool in type 1 diabetes. The software is designed to enable researchers to rapidly streamline laboratory research through the evaluation of alternative scenarios for therapeutic strategies that show the most promise for working in humans.

"Since laboratory studies can cost hundreds of thousands of dollars, and early stage human clinical trials can cost $10 million dollars or more, predicting the right conditions to try is important," said Dr. von Herrath, director of the Type 1 Diabetes Research Center at the La Jolla Institute for Allergy & Immunology, where the studies were conducted.

"We've found that using this in silico (computer analysis) prediction platform can quicken the pace and effectiveness of type 1 diabetes research," he continued. "By allowing us to pre-test our theories in computer models, we can ensure that the more time-intensive and costly process of laboratory testing is focused on the most promising therapeutic strategies, with the greatest chance of success."

The platform, developed by Entelos Inc., a life sciences company specializing in predictive technologies, has previously been shown to successfully predict various data from published type 1 diabetes experiments. Dr. von He
'/>"/>

Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. La Jolla Institute scientist Klaus Ley receives Malpighi award
2. La Jolla Institute scientist leads team which discovers important new player in diabetes onset
3. Visionary concept earns La Jolla Institute scientist prestigious NIH Pioneer Award
4. La Jolla Institute discovers novel tumor suppressor
5. La Jolla Institute signs exclusive license agreement with Medimmune on major asthma discovery
6. IP-K extends research deal with Novartis Institute for Tropical Diseases
7. Rensselaer Polytechnic Institute professor Georges Belfort wins biochemical engineering award
8. Salk Institute creates Renato Dulbecco Chair in Genomics and Roger Guillemin Chair in Neuroscience
9. Helmsley Charitable Trust awards more than $15 million to Salk Institute-CUMC
10. Durham Energy Institute to advise government on green technology
11. BMC receives National Institutes of Health grant to study intrauterine cocaine and substance reslience
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2015)... DUBLIN , May 28, 2015 ... the addition of the "Facial Recognition Market ... User - Global Forecast to 2020" report ... years, have seen facial recognition technology become more ... technology to gain traction and investment from the ...
(Date:5/27/2015)... , May 27, 2015   Codonics ... safety systems and image documentation solutions and ... comprehensive, technologically-advanced automation solutions, is pleased to ... The Codonics® Safe Label System® (SLS), an ... conjunction with the Omnicell Anesthesia Workstation, helps ...
(Date:5/25/2015)... 2015  Australia,s market for wearable technologies is considered ... the advent of several trials and prototypes. The release ... expected to ignite interest in wearables as well as ... . This in turn will spur greater innovation ... partnerships amongst vendors and distributors. Photo ...
Breaking Biology News(10 mins):Global advanced Facial Recognition Market Expected to Grow From $2.77 Billion in 2015 to $6.19 Billion in 2020, at an Estimated CAGR of 17.4% 2Codonics and Omnicell Expand Partnership 2Codonics and Omnicell Expand Partnership 3Codonics and Omnicell Expand Partnership 4Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4
... . Vitamin B12 is vital for cell division, the ... system. Unable to produce the vitamin itself, the human body has ... known that on its way into the cell vitamin B12 is ... the cell interior with the aid of the transport protein CblF, ...
... Department of Energy,s Lawrence Berkeley National Laboratory (Berkeley Lab) found ... improved sperm DNA quality in older men. In younger men, ... DNA. In an analysis of 80 healthy male volunteers ... that men older than 44 who consumed the most vitamin ...
... California Institute of Technology (Caltech) have made the first-ever ... molecules one at a time. This new ... diseases, enable biologists to study viruses and probe the ... better measure nanoparticles and air pollution. The ...
Cached Biology News:Vitamin B12 deficiency: Tracing the causes 2Nutrition tied to improved sperm DNA quality in older men 2Nutrition tied to improved sperm DNA quality in older men 3Weighing molecules 1 at a time 2Weighing molecules 1 at a time 3Weighing molecules 1 at a time 4
(Date:6/3/2015)... DUBLIN , June 02, 2015 /PRNewswire/ ... has announced the addition of the ... Testing Market" report to their offering. ... analysis of the US immunoprotein diagnostic market, ... market shares, and strategic profiles of leading ...
(Date:6/3/2015)... -- Findings presented at the European Organization ... of NeuroOncology (EANO) and European Society for Medical Oncology ... that EDO-S101 is effective in models of human glioblastoma ... radiotherapy (RT). [ 1 ] ... that combines the DNA damaging effect of bendamustine with ...
(Date:6/3/2015)... 2015 On April 21, 2015, California ... Communications Committee (11-0) and indicates the legislature's desire to support ... , The Committee Chairman supports the bill and would like ... 8,000 GWh and would also like to see any new ... This “Wait List” and timing are extremely important. , To ...
(Date:6/3/2015)... 2015 Typical racks for laboratory freezers ... and depths often taking up unnecessary room in already ... Low 5 Box Freezer Racks offer a customizable ... freezer storage boxes and freezers. , “These racks ... experiments or multiple people because users can configure freezer ...
Breaking Biology Technology:United States Strategies in the Immunoprotein Diagnostic Testing Market Report 2015 2Mundipharma EDO GmbH Data Confirm EDO-S101 is Effective in Preclinical Models of Human Glioblastoma 2Mundipharma EDO GmbH Data Confirm EDO-S101 is Effective in Preclinical Models of Human Glioblastoma 3Mundipharma EDO GmbH Data Confirm EDO-S101 is Effective in Preclinical Models of Human Glioblastoma 4Bmark Energy Announces the Sign-up Deadline for Companies Interested in California’s Direct Access Program is June 12th, 2015 at 5:00pm. 2Freezer Space Can Now Be Configured Your Way with New Modular Freezer Racks 2
... , BEIJING, China , July 6 ... the development, assembly,marketing and sale of medical devices and homecare medical products in ... EPS for,fiscal year 2010. , , ... (Logo: http://photos.prnewswire.com/prnh/20100422/CNTH001LOGO ) , ...
... Cellectis (Alternext: ALCLS), the French genome engineering specialist, announced today ... by Taconic Artemis and Taconic Farms Inc in December 2008 ... , , , ... of the Tribunal de Grande Instance decided on Tuesday, June 29 ...
... July 6 Novavax, Inc. (Nasdaq: NVAX ... M.D., as the company,s Chief Scientific Officer who will report ... Officer of Novavax.  Previously, Dr. Glenn was Chief Scientific Officer ... international health at Johns Hopkins University,s School of Public ...
Cached Biology Technology:Dehaier Medical Systems Reaffirms Earnings Estimate of $0.80 EPS for FY 2010 2Dehaier Medical Systems Reaffirms Earnings Estimate of $0.80 EPS for FY 2010 3Dehaier Medical Systems Reaffirms Earnings Estimate of $0.80 EPS for FY 2010 4Taconic's Litigation Contesting License Termination By Cellectis Is Dismissed 2Taconic's Litigation Contesting License Termination By Cellectis Is Dismissed 3Novavax Announces Appointment of Dr. Gregory Glenn as Chief Scientific Officer 2Novavax Announces Appointment of Dr. Gregory Glenn as Chief Scientific Officer 3Novavax Announces Appointment of Dr. Gregory Glenn as Chief Scientific Officer 4