Navigation Links
LSUHSC's Kolls awarded $1.8 million to improve vaccine strategies for P. carinii pneumonia
Date:7/7/2009

New Orleans, LA Jay K. Kolls, MD, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans School of Medicine, has been awarded $1.8 million over five years by the National Heart, Lung and Blood Institute of the National Institutes of Health to study whether antibodies that recognize carbohydrate (sugars) and proteins on the surface of the fungus that causes Pneumocystis carinii pneumonia (PCP) can be used to prevent the infection. Pneumocystis carinii pneumonia remains a serious complication in patients with weakened immune systems, such as those with AIDS, cancer, chronic conditions treated with corticosteroids, or organ transplant recipients.

Earlier research by Dr. Kolls found that carbohydrate antibodies are part of the natural response to the Pneumocystis fungus. Theses preliminary studies show that these antibodies participate in early clearance of the organism from the lung as well as regulate long term immune responses to the organism. The research team believes that this response might be harnessed to develop a vaccine to prevent or better treat infections from this fungus.

This funding will advance the research seeking not only to confirm that anti-carbohydrate antibodies are part of the natural response repertoire to the Pneumocystis fungus, but also that when combined with a potent protein antigen called Kex1, these antibodies can regulate direct killing of the fungus and confer immunity.

"Understanding these antibody responses will improve vaccine strategies for this human infection," notes Dr. Jay Kolls, who is also the principal investigator on the grant.


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Page: 1

Related biology news :

1. NYU Langone Medical Center awarded NIH grants totaling $1,560,000
2. Ernst-Ludwig Winnacker awarded the Order of the Rising Sun
3. University of Liverpool awarded $3.3 million for genomics hub
4. UCI awarded $45 million for infectious disease research
5. University awarded £1.7M to develop nanotechnology for use in health care
6. LSUHSC student awarded top national honor for diabetes research
7. CSC Awarded $570 Million IT Services Contract by UK Identity and Passport Service
8. Jefferson researcher awarded Landenberger Foundation grant for ALS research
9. CSC Awarded $570 Million IT Services Contract by UK Identity and Passport Service
10. UC and partners awarded $23 million to transform discoveries into real-world health solutions
11. Jonathan Berg, M.D., Ph.D. awarded Richard King Trainee Award for Best in Genetics in Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2016)... 2016 "The biometric system ... The biometric system market is in the growth ... near future. The biometric system market is expected to ... a CAGR of 16.79% between 2016 and 2022. Government ... technology in smartphones, rising use of biometric technology in ...
(Date:11/21/2016)...   Neurotechnology , a provider of high-precision ... that the MegaMatcher On Card fingerprint matching algorithm ... NIST Minutiae Interoperability Exchange (MINEX) III ... of the evaluation protocol. The ... fingerprint templates used to establish compliance of template ...
(Date:11/16/2016)... SANTA CLARA, Calif. , Nov. 16, 2016 /PRNewswire/ ... company enhancing user experience and security for consumer ... provider for the financial and retail industry, today ... more secure and convenient way to authenticate users ... now uses Sensory,s TrulySecure™ software which ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... South Korea , Dec. 8, 2016 ... a $21 billion KRW (US $18.9M) Series A financing. ... Kolon Investment, G.N. Tech Venture and SNU Bio Angel. ... Eutilex to 30.5 billion KRW (US $27.7M) since its ... help Eutilex to bolster the development and commercialization of ...
(Date:12/8/2016)... Dec. 8, 2016   Biocept, Inc . ... provider of clinically actionable liquid biopsy tests to ... clinical data featuring its Target Selector™ Circulating Tumor ... for the detection of actionable biomarkers in patients ... sponsored by Sara Cannon Research Institute (SCRI), the ...
(Date:12/7/2016)... ... 07, 2016 , ... A new study published in the ... treated, advanced pancreatic cancer, liquid biopsies are not yet an adequate substitute for ... blood sampling may improve the value of a blood-based test.” The study was ...
(Date:12/7/2016)... Neogen Corporation (NASDAQ: NEOG ) ... as its chief science officer — a new ... at Neogen effective Jan. 1. Kephart has ... unit of Thermo Fisher Scientific, as well as animal ... extensive industry experience also includes the management of a ...
Breaking Biology Technology: