Navigation Links
LSUHSC's Kolls awarded $1.8 million to improve vaccine strategies for P. carinii pneumonia
Date:7/7/2009

New Orleans, LA Jay K. Kolls, MD, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans School of Medicine, has been awarded $1.8 million over five years by the National Heart, Lung and Blood Institute of the National Institutes of Health to study whether antibodies that recognize carbohydrate (sugars) and proteins on the surface of the fungus that causes Pneumocystis carinii pneumonia (PCP) can be used to prevent the infection. Pneumocystis carinii pneumonia remains a serious complication in patients with weakened immune systems, such as those with AIDS, cancer, chronic conditions treated with corticosteroids, or organ transplant recipients.

Earlier research by Dr. Kolls found that carbohydrate antibodies are part of the natural response to the Pneumocystis fungus. Theses preliminary studies show that these antibodies participate in early clearance of the organism from the lung as well as regulate long term immune responses to the organism. The research team believes that this response might be harnessed to develop a vaccine to prevent or better treat infections from this fungus.

This funding will advance the research seeking not only to confirm that anti-carbohydrate antibodies are part of the natural response repertoire to the Pneumocystis fungus, but also that when combined with a potent protein antigen called Kex1, these antibodies can regulate direct killing of the fungus and confer immunity.

"Understanding these antibody responses will improve vaccine strategies for this human infection," notes Dr. Jay Kolls, who is also the principal investigator on the grant.


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Page: 1

Related biology news :

1. NYU Langone Medical Center awarded NIH grants totaling $1,560,000
2. Ernst-Ludwig Winnacker awarded the Order of the Rising Sun
3. University of Liverpool awarded $3.3 million for genomics hub
4. UCI awarded $45 million for infectious disease research
5. University awarded £1.7M to develop nanotechnology for use in health care
6. LSUHSC student awarded top national honor for diabetes research
7. CSC Awarded $570 Million IT Services Contract by UK Identity and Passport Service
8. Jefferson researcher awarded Landenberger Foundation grant for ALS research
9. CSC Awarded $570 Million IT Services Contract by UK Identity and Passport Service
10. UC and partners awarded $23 million to transform discoveries into real-world health solutions
11. Jonathan Berg, M.D., Ph.D. awarded Richard King Trainee Award for Best in Genetics in Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... PUNE, India , March 28, 2017 ... (Analog, IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), ... Maintenance), Vertical, and Region - Global Forecast to 2022", ... 30.37 Billion in 2016 and is projected to reach ... 15.4% between 2017 and 2022. The base year considered ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), ... published by MarketsandMarkets, the market is expected to be worth USD 18.98 billion ... Continue Reading ... ...      (Logo: ...
(Date:3/22/2017)... March 21, 2017 Vigilant Solutions , ... law enforcement agencies, announced today the appointment of retired ... of public safety business development. Mr. Sheridan ... experience, including a focus on the aviation transportation sector, ... recent position, Mr. Sheridan served as the Aviation Liaison ...
Breaking Biology News(10 mins):
(Date:7/18/2017)... ... 18, 2017 , ... Blood centers traditionally see a dangerous drop of blood ... a struggle for community blood centers as high schools are out and many frequent ... is teaming up with the South Texas Blood & Tissue Center ...
(Date:7/17/2017)... ... July 17, 2017 , ... The Academy of Model Aeronautics ... National Model Aviation Day will take place from 9 a.m. to 2 p.m. at ... activities for all ages. , Aviation Adventure Day will be packed with entertaining activities ...
(Date:7/17/2017)... ... July 17, 2017 , ... Panitch Schwarze Belisario & ... the BiG (Biomedical Innovation Group) annual meeting in China. , This year’s meeting, ... receptor T-cell) therapy, a rapidly developing highly personalized anti-cancer technology that involves removing ...
(Date:7/16/2017)... ... 16, 2017 , ... OHAUS Corporation, a leading worldwide manufacturer ... new line of Extreme Environment Shakers today. , Extreme Environment Shakers , OHAUS ... optimal cell growth such as cell cultures, solubility studies and extraction procedures. These ...
Breaking Biology Technology: