Navigation Links
LSUHSC scientist awarded nearly $2 million to determine role of biofilms in common fungal infection
Date:2/6/2013

New Orleans, LA Mairi Noverr, PhD, Associate Professor in the Department of Prosthodontics at the LSU Health Sciences Center New Orleans School of Dentistry, has been awarded a $1.7 million grant over five years by the National Institute of Dental & Craniofacial Research of the National Institutes of Health to study the role of biofilms in infection and disease. This research will contribute to our understanding of how biofilms are involved in fungal disease development, leading to the discovery of new therapeutic targets.

Dr. Noverr, a microbiologist, is studying a model of dental stomatitis, a fungal infection affecting approximately 50-75% of otherwise healthy denture wearers, and C. albicans, the most common infection-causing yeast. C. albicans normally lives on the skin and mucous membranes without any problem. But its overgrowth can result in infection. C. albicans is the most common cause of denture stomatitis. C. albicans readily forms biofilm on denture materials; however, the role of biofilm formation in the disease development process of denture stomatitis is unknown. Biofilms are the sticky substances composed of microorganisms like yeasts, bacteria, etc. that form on and adhere to wet surfaces including teeth, dental prostheses, or implants. Dental plaque is an example of a biofilm.

The major goals of this grant are to determine the role of biofilm formation in Candida-associated denture stomatitis and determine how the immune response influences development of the disease.

"Information gathered in these studies can be applied to other Candida mucosal and device-related biofilm infections, which can cause systemic infection and significant illness and death," notes Dr. Noverr, who is also a member of the LSUHSC Center of Excellence in Oral Biology. "Because biofilms are not only resistant to antimicrobial drugs but also to immune defenses, this knowledge base can be used to dev
'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. LSUHSC research discovery provides therapeutic target for ALS
2. LSUHSCs Weiss chosen to help set national eye policy, research
3. LSUHSC research identifies new therapeutic target for Alzheimers disease
4. LSUHSC research finds ginkgo biloba doesn’t improve cognitive function in MS
5. LSUHSC research finds treating stress prevented new MS brain lesions
6. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
7. Scientists turn toxic by-product into biofuel booster
8. Scientists find a key element of lupus, suggesting better drug targets
9. Scientists notch a win in war against antibiotic-resistant bacteria
10. Plant scientists at CSHL demonstrate new means of boosting maize yields
11. Listening to cells: Scientists probe human cells with high-frequency sound
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... of the "Micro Market Monitor: North America Perimeter ... http://photos.prnewswire.com/prnh/20130307/600769 The ... at a CAGR of 3.6% from 2014 to 2019. ... this market, Canada is expected ...
(Date:12/17/2014)... , Dec. 15, 2014 Research and ... the addition of the "Samsung Galaxy S5 ... report to their offering. ... a totally different sensing technology than the iPhone ... fingerprint sensor in its product. The ...
(Date:12/17/2014)... 2014 Valencell, a leader in performance biometric ... to industry leaders such as Intel, Jabra, Atlas, and ... wearable products. These products will be showcased at CES ... Vegas . "Our partners choose ... robust – with the clinical data to back it ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... recent study led by scientists from the National University of ... Spinal Muscular Atrophy (SMA), a devastating disease that is the ... young adults. As there is currently no known cure for ... fight against SMA. SMA is caused by deficiencies ...
... , Dec. 18, 2013 Tissue engineering ... a regenerative or reparative medicine with potential to ... engineering, which involve leveraging technologies from biomaterials, molecular ... the restructure and/or repair of human organs through ...
... have shown for the first time that the specialised role ... cilia tiny hair-like structures protruding from a cell. Stem ... body through the process of differentiation. The discovery ... therapies for a range of medical treatments where scientists aim ...
Cached Biology News:Study led by NUS scientists provides new insights into cause of human neurodegenerative disease 2Study led by NUS scientists provides new insights into cause of human neurodegenerative disease 3State-of-the-Art Tissue Engineering and Organ Regeneration Technologies Yield Healthcare Market Disruption 2State-of-the-Art Tissue Engineering and Organ Regeneration Technologies Yield Healthcare Market Disruption 3State-of-the-Art Tissue Engineering and Organ Regeneration Technologies Yield Healthcare Market Disruption 4
(Date:12/24/2014)... 23, 2014 On Friday, December ... 83, the Omnibus and Continuing Resolution Appropriations Act ... hydrocephalus a condition eligible to receive funding through ... by the Department of Defense (DoD). The Hydrocephalus ... on Capitol Hill, is celebrating this victory for ...
(Date:12/24/2014)... 23, 2014 Pipette.com announces their ... followers can submit their #HolidayInTheLab pictures for a chance ... mates. , For those struggling to think of a ... Holiday in the Lab Contest provides the ideal holiday ... to send pictures of their chemistree, holiday sweaters, ...
(Date:12/24/2014)... 23, 2014  Rock Creek Pharmaceuticals, Inc., (NASDAQ: ... a Clinical Trial Application (CTA) with the ... (MHRA) seeking regulatory approval to initiate clinical trials for ... Contingent on the Company receiving CTA regulatory ... trial to assess the safety, tolerability and dose escalation ...
(Date:12/22/2014)... N.C. , Dec. 22, 2014  Alternative ... announced that it has signed a letter of ... that has developed and patented a nanotechnology-based development ... diagnostics products that enable rapid on-site collection and ... use/abuse and health issues in an immediate, non-invasive ...
Breaking Biology Technology:Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3ALNE Announces Intention To Acquire BioTechPharma 2
... 16 BioEnergy International, ... of next-generation, renewable biochemicals and biofuels, announces the ... all of its biobased chemicals business and intellectual ... biofuels opportunities, including its 110 million gallon per ...
... June 16 Wyeth (NYSE: WYE ) (the ... Senior Debentures due 2024 (the "Convertible Debentures") have the right ... to their terms effective on the July 15, 2009 purchase ... in aggregate principal amount of Convertible Debentures outstanding. , ...
... Wound Care Innovations, LLC, a subsidiary of Wound ... reached an agreement in principle to acquire BioPharma Management ... platform of proprietary and patented technologies for topical pain ... structured as a share exchange pursuant to which BioPharma ...
Cached Biology Technology:BioEnergy International, LLC Announces Formation of Myriant Technologies LLC 2Wyeth Announces Holder Right to Surrender Convertible Debentures 2Wyeth Announces Holder Right to Surrender Convertible Debentures 3Wyeth Announces Holder Right to Surrender Convertible Debentures 4Wound Management Technologies, Inc. Announced Today That It Has Reached an Agreement in Principal to Acquire BioPharma Management Technologies, Inc. 2
Template and primers for preparation of internal control spots...
Template and primers for preparation of internal control spots...
ANTI FLAG EP CL VEC...
RAT ANTI MOUSE JAM-2 Immunogen: Recombinant soluble JAM-2...
Biology Products: