Navigation Links
LSUHSC research finds combo of plant nutrients kills breast cancer cells
Date:11/22/2013

New Orleans, LA A study led by Madhwa Raj, PhD, Research Professor in Obstetrics and Gynecology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, has found that a super cocktail of six natural compounds in vegetables, fruits, spices and plant roots killed 100% of sample breast cancer cells without toxic side effects on normal cells. The results, which also revealed potential treatment target genes, are published in the November 2013 issue of The Journal of Cancer.

"One of the primary causes of both the recurrence of breast cancer and deaths is a small group of cancer stem cells that evade therapy," notes Dr. Raj. "These often multi-drug-resistant cells have the ability to generate new tumors, so it is critically important to develop new approaches to more effective and safer treatment or prevention of breast cancer."

The research team tested ten known protective chemical nutrients found in foods like broccoli, grapes, apples, tofu, and turmeric root (a spice used in Indian curry) before settling upon six Curcumin known as tumeric, Isoflavone from soybeans, Indo-3-Carbinol from cruciferous plants, C-phycocyanin from spirulina, Reservatrol from grapes, and Quercetin, a flavonoid present in fruits, vegetables, and tea. The researchers administered these six at bioavailable levels to both breast cancer and control cells. They tested the compounds individually and in combination. They found that the compounds were ineffective individually. When combined, though, the super cocktail suppressed breast cancer cell growth by more than 80%, inhibited migration and invasion, caused cell cycle arrest, and triggered the process leading to cell death resulting in the death of 100% of the breast cancer cells in the sample. The researchers observed no harmful effects on the control cells. Further analysis also identified several key genes, which could serve as markers to follow the progress of therapy.

Although the cockta
'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. LSUHSCS OCHOA 1 of 10 chosen by NIH director for Transformative Research Award
2. LSUHSC researchers develop new system to better study behavior, cell function
3. LSUHSC researcher awarded NCI grant to study link between chronic inflammation and cancer
4. LSUHSC research identifies new risk factors for parasitic infection
5. LSUHSC research discovers new drug target for metastatic breast cancer
6. LSUHSC research identifies co-factors critical to PTSD development
7. LSUHSC scientist awarded nearly $2 million to determine role of biofilms in common fungal infection
8. LSUHSC research discovery provides therapeutic target for ALS
9. LSUHSCs Weiss chosen to help set national eye policy, research
10. LSUHSC research identifies new therapeutic target for Alzheimers disease
11. LSUHSC research finds ginkgo biloba doesn’t improve cognitive function in MS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
(Date:12/10/2014)... California , December 9, 2014 ... with ITN,s BCARD Platform   ... cloud-based enterprise meeting scheduling solutions for business-to-business (B2B) ... the world leader in mobile near-field communication (NFC), ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , ...
(Date:12/5/2014)... , Dec. 4, 2014  Tute Genomics, a ... $2.3 million in Series A1 funding led by UK-based ... also participated in the investment round. "We ... healthcare community adopts next-generation sequencing and seeks new approaches ... Reid Robison , MD MBA, and CEO of ...
Breaking Biology News(10 mins):Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3
... showed that they could cut the lives of disease-carrying mosquitoes ... from fruit flies. Now, a new report in the December ... suggests that their strategy might do one better: The Wolbachia ... viruses that are a growing threat to humans, including those ...
... Scientists have shown for the first time that insects, ... They made the discovery thanks to high-speed video cameras ... that they used to film desert locusts stepping along ... new light on insects, ability to perform complex tasks, such ...
... Glaciers along the Gulf of Alaska are enriching stream and ... carbon contained in glacial runoff, researchers from four universities and ... issue of the journal Nature *. In ... Environmental Science Program at the University of Alaska Southeast, set ...
Cached Biology News:New tool in the fight against mosquito-borne disease: A microbial 'mosquito net' 2Ladder-walking locusts show big brains aren't always best 2Glacier melt adds ancient edibles to marine buffet 2
(Date:12/24/2014)... (PRWEB) December 23, 2014 ... series is designed to introduce cutting edge ... users and partners of platform upgrades. This ... benefits; empowering users in their quest to ... tools. , According to SoundConnect’s Marketing Manager, ...
(Date:12/24/2014)... 2014 The report provides ... its definition, classification, application and industry overview. ... process, and product cost structure. Production is ... analysis also covers upstream raw materials, equipment, ... trend and proposals. In the end, the ...
(Date:12/24/2014)... 2014 Pipette.com announces their Holiday ... can submit their #HolidayInTheLab pictures for a chance to ... , For those struggling to think of a holiday ... in the Lab Contest provides the ideal holiday presents. ... to send pictures of their chemistree, holiday sweaters, as ...
(Date:12/24/2014)... 23, 2014 PharmaBoardroom,s new ... today and available for free download , digs deep ... and growth in the sector today. One area ... has been in developing a homegrown pharmaceutical manufacturing base, even ... still remains some way off. A cursory comparison with neighboring ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3
... 2011 Psoriasis is a persistent, long-lasting chronic skin ... more than 125 million individuals.  For some, it is ... On a continuing quest to find more effective ... Journal of Investigative Dermatology reported that the ...
... 14, 2011 Merriman Capital, ... (NASDAQ: MERR ), today announced that it ... Circadian Technologies Limited (ASX: CIR; OTCQX: CKDXY) as it ... http://photos.prnewswire.com/prnh/20100914/SF64919LOGO ) Circadian is an Australian biotechnology ...
... June 14, 2011 OncoSec Medical Inc. (OTCBB: ... to treat solid tumor cancers, announced today two ... the clinical operations of OncoSec,s ElectroOncology therapies. ... Dhillon, OncoSec,s President and CEO, said, "OncoSec has ...
Cached Biology Technology:Actinobac Biomed, Inc. Demonstrates In Vivo Efficacy for Psoriasis Treatment 2Merriman Capital Announces Sponsorship of Circadian Technologies on OTCQX 2Merriman Capital Announces Sponsorship of Circadian Technologies on OTCQX 3OncoSec Announces Clinical Leadership Appointments 2OncoSec Announces Clinical Leadership Appointments 3OncoSec Announces Clinical Leadership Appointments 4
... the biological data hidden in your samples with ... allows you to create your own microarray designs ... your own pace and receive delivery of your ... is a secure, online array creation application tool ...
Acetylcholinesterase (human brain, AChE)...
... meets the demands of the routine trace ... from reliable, robust and simple to use ... in the most challenging sample matrices found ... suited to the toughest analytical challenges found ...
C1-inhibitor (C1-INH)...
Biology Products: