Navigation Links
LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
Date:3/29/2012

New Orleans, LA Research led by Lauren Cole, a public health graduate student, and Dr. Edward Peters, Associate Professor of Public Health and Director of the Epidemiology Program at LSU Health Sciences Center New Orleans, reports that the incidence of head and neck cancer has risen at sites associated with Human Papilloma Virus (HPV) infection, with the greatest increase among middle-aged white men. At the same time, younger, Non-Hispanic blacks experienced a substantial decrease in these cancers. They also found that the disease process for tumors associated with HPV is different from those caused by exposure to tobacco and alcohol, with implications for treatment. The findings are published this month in the PLoS ONE journal.

Tobacco and alcohol are the most common risk factors for cancers of the head and neck, but HPV infection is emerging as an important risk factor as well. The objectives of this study were to assess the recent incidence of head and neck cancer in the United States and to investigate the trends of these cancers associated with HPV infection.

Using incidence data for 1995-2005 from 40 US population-based cancer registries, the researchers described the epidemiology of head and neck cancer (HNC) in the US and examined the variation in cancer rates by age, sex, race/ethnicity, stage and cancer location. As some HNC sites are strongly associated with a tendency for HPV infection, they also examined if rates varied by those sites associated with HPV.

"During 1995-2005, we observed a significant overall increase in head and neck cancer incidence among HPV-associated sites, while in the same time period, non HPV-associated sites underwent a significant decline in incidence," notes Lauren Cole, an Epidemiology PhD student at LSU Health Sciences Center New Orleans School of Public Health.

The researchers found overall, younger age groups, Non-Hispanic Whites and Hispanics experienced greater increases in incidence for HPV-associated sites, while incidence declined for Non-Hispanic Blacks independent of HPV-association of site. The evidence from this large population-based study suggests that since the disease process for HPV-associated tumors is different, HPV tumor status should be incorporated into treatment decisions for head and neck cancer patients to improve prognosis and survival.

"With the introduction of the HPV vaccine, this study suggests that the vaccine can not only be used to help prevent cervical cancer, but head and neck cancer as well," adds Dr. Edward Peters, Associate Professor and Director of the Epidemiology Program at the LSU Health Sciences Center New Orleans School of Public Health.

Head and neck cancer includes cancer in the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx (voice box). According to the National Cancer Institute, head and neck cancers account for approximately 3 percent of all cancers in the United States. These cancers are nearly twice as common among men as they are among women. Head and neck cancers are also diagnosed more often among people over age 50 than they are among younger people. More than 52,000 men and women in this country were expected to be diagnosed with head and neck cancers last year.
'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Related biology news :

1. LSUHSCs Gee honored for improving health of women, children and families
2. LSUHSC conducts landmark study of mid, long-term health effects of oil exposure
3. LSUHSC reports first successful salivary stone removal with robotics
4. LSUHSC study IDs proteins regulating water retention in salt-sensitive hypertension
5. LSUHSC awarded $12 million for cancer, infectious diseases research & research pipeline
6. LSUHSC pediatric weight expert provides obesity trinity answers
7. LSUHSC awarded $2 million dollar grant to prevent pneumonia linked to immune deficiency
8. LSUHSC awarded $4 million to understand effect of THC on HIV
9. LSUHSC researcher finds surprising link between sugar in drinks and blood pressure
10. LSUHSC research increases understanding of drug metabolism
11. LSUHSC researcher finds first inherited prostate cancer genetic mutation in African-American men
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
(Date:3/31/2016)...  Genomics firm Nabsys has completed a financial  restructuring ... , M.D., who returned to the company in October ... team, including Chief Technology Officer, John Oliver , ... and Vice President of Software and Informatics, Michael ... Dr. Bready served as CEO of Nabsys from 2005-2014 ...
(Date:3/22/2016)... Ontario , PROVO and ... Newborn Screening Ontario (NSO), which operates the ... for molecular testing, and Tute Genomics and UNIConnect, ... management technology respectively, today announced the launch of a ... next-generation sequencing (NGS) testing panel. NSO ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Liquid Biotech ... announced the funding of a Sponsored Research Agreement ... circulating tumor cells (CTCs) from cancer patients.  The ... in CTC levels correlate with clinical outcomes in ... These data will then be employed to support ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal articles ... findings are the subject of a new article on the Surviving Mesothelioma website. ... blood, lung fluid or tissue of mesothelioma patients that can help point doctors to ...
(Date:6/23/2016)... June 23, 2016 A person commits a crime, ... scene to track the criminal down. An outbreak ... and Drug Administration (FDA) uses DNA evidence to track down ... Sound far-fetched? It,s not. The FDA has increasingly used ... investigations of foodborne illnesses. Put as simply as possible, whole ...
(Date:6/23/2016)... 2016   EpiBiome , a precision microbiome engineering ... debt financing from Silicon Valley Bank (SVB). The financing ... advance its drug development efforts, as well as purchase ... "SVB has been an incredible strategic partner to us ... bank would provide," said Dr. Aeron Tynes Hammack ...
Breaking Biology Technology: