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LSUHSC awarded $10M+ COBRE grant
Date:7/9/2008

nationally funded investigators in New Orleans and the State of Louisiana," says Kapusta. He also adds, "This COBRE grant provides a platform to transition our cardiovascular biology program to a self-sustaining and nationally recognized Cardiovascular Center of Excellence at LSUHSC. The need for such a mission is apparent from the tragic state of cardiovascular disease not only in the United States, but within our home state of Louisiana."

The funding will support four research projects and one pilot project of LSUHSC junior faculty investigators. Junior faculty are Eric Lazartigues, PhD, LSUHSC Assistant Professor of Pharmacology, T. Cooper Woods, PhD, LSUHSC Instructor of Pharmacology who is also a Staff Scientist at Ochsner Clinic Foundation, Catalin Filipeanu, MD, PhD, LSUHSC Assistant Professor-Research of Pharmacology, Jerome Breslin, PhD, LSUHSC Assistant Professor of Physiology, and Developing Investigator Hernan Bazan, MD, LSUHSC Assistant Professor of Surgery.

Dr. Lazartigues' project will examine a newly discovered component of blood pressure regulation called ACE2 to determine its significance in the development of hypertension. Dr. Woods's project will help to explain why diabetics who have stents placed in their coronary arteries are at increased risk for re-stenosis or reclosure of the arteries. Dr. Filipeanu's project will study how specific proteins in cells of blood vessels cause excessive contraction which leads to discoloration and pain in the fingers and toes of patients with Raynaud Phenomenon. Dr. Breslin's work will increase our understanding of the basic mechanisms of blood-tissue exchange and the potentially life-threatening fluid leakage involved in inflammation, cardiovascular disease, diabetes, and sepsis. Dr. Bazan's project is designed to fill major gaps in our knowledge regarding the process of carotid plaque instability and rupture resulting in stroke.

"In the state of Louisiana, the incidence rate for ca
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Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Science Center
Source:Eurekalert

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