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LSTM researchers among first to sequence snake genome
Date:12/3/2013

e are the first snake genomes to be sequenced and fully annotated and our results in relation to the king cobra provide a unique view of the origin and evolution of snake venom, including revealing multiple genome-level adaptive responses to natural selection in this complex biological weapon system. These adaptations include the massive and rapid expansion of gene families that produce venom toxins, providing the snake with a highly toxic protein mixture required to overcome a variety of different prey and also circumvent any resistance to venom that may have developed in such prey. Our study provides unique genome-wide perspectives on the adaptive evolution of venom systems as well as protein evolution in general. As such it contributes an essential foundation for understanding and comparing evolutionary genomic processes in venomous organisms."

The work carried out by Dr Casewell and his co-authors was used in the second paper outlining the analysis of the genome of the Burmese python, also published in the same edition of PNAS.


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Contact: Clare Bebb
c.bebb@liv.ac.uk
44-015-170-53135
Liverpool School of Tropical Medicine
Source:Eurekalert

Page: 1 2

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