Navigation Links
LSTM begins £0.5 million malaria study in Burkina Faso

A new study led by LSTM will investigate whether long-term weekly iron and folic acid supplementation can reduce anaemia without increasing the risk of contracting malaria. The information provided by the study, based in Burkina Faso and running until 2014, will strengthen adolescent health services and develop effective preventative programmes for anaemia control in young women.

Young women who conceive during or shortly after adolescence may enter pregnancy with deficient iron stores due to their development and the onset of menstruation. This can be offset with iron supplementation but there is some evidence that this can increase the risk of contracting malaria. Many young women tend not to present at antenatal clinics until mid-pregnancy and are therefore unlikely to be protected from malaria at the most susceptible period in early pregnancy.

Professor Bernard Brabin, Head of LSTM's Child and Reproductive Health department, has secured a 0.5 million grant from the US National Institutes of Health, through support from the Bill & Melinda Gates Foundation, to test the hypothesis that iron supplementation in young women prior to conception and during early pregnancy results in reduced iron deficiency and anaemia in pregnancy without increasing malaria risk. The study is being conducted in partnership with the Centre Muraz in Burkina Faso and the Institute of Tropical Medicine in Antwerp.

Professor Brabin explained: "As young women who are pregnant for the first time are particularly susceptible to the risks of malaria in pregnancy, it is essential to assess the safety of long term weekly supplementation, an approach now recommended by the World Health Organization. Some fifty million pregnant women are at risk of malaria every year but there are only four published studies of the effects of iron treatments during pregnancy on the prevalence of both malaria and anaemia and none on malaria risks in early pregnancy."

The study will look at the differences in malaria parasite prevalence, the incidence of clinical malaria and the prevalence of iron deficiency and anaemia between two randomised groups, one receiving iron supplementation and the other a placebo. Qualitative studies will assess adherence to weekly iron supplementation. The subjects will be followed from enrolment through conception to their first antenatal visit and delivery. The trial will be conducted according to the principles of good clinical practice and wil be reviewed by Ethical Committees in the three partner countries.

Professor Brabin continued: "Once we have a definitive answer to whether supplementation is safe, we will be able to inform the way adolescent health services are promoted, with the aim to develop more effective preventative programmes for anaemia control in young women."


Contact: Alan Hughes
Liverpool School of Tropical Medicine

Related biology news :

1. Study begins to reveal clues to the cause and progression of sepsis
2. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
3. DHS Begins Collecting 10 Fingerprints From International Visitors at Washington Dulles International Airport
4. UC San Diego begins trading greenhouse gas credits on Chicago Climate Exchange
5. DHS Begins Collecting 10 Fingerprints From International Visitors at Hartsfield-Jackson Atlanta International Airport
6. Exploration of lake hidden beneath Antarcticas ice sheet begins
7. DHS Begins Collecting 10 Fingerprints From International Visitors at Boston Logan International Airport
8. DHS Begins Collecting 10 Fingerprints From International Visitors at Chicago OHare International Airport
9. DHS Begins Collecting 10 Fingerprints From International Visitors at George Bush Houston Intercontinental Airport
10. DHS Begins Collecting 10 Fingerprints From International Visitors at San Francisco International Airport
11. DHS Begins Collecting 10 Fingerprints From International Visitors at Miami International Airport
Post Your Comments:
(Date:11/17/2015)... -- Paris from 17 th ... Paris from 17 th until 19 th ... has invented the first combined scanner in the world which ... surface. Until now two different scanners were required: one for ... on the same surface. This innovation is an ideal ...
(Date:11/12/2015)...  A golden retriever that stayed healthy despite having ... provided a new lead for treating this muscle-wasting disorder, ... of MIT and Harvard and the University of São ... Cell, pinpoints a protective gene that boosts ... The Boston Children,s lab of Lou Kunkel , ...
(Date:11/10/2015)... , Nov. 10, 2015 ... biometrics that helps to identify and verify the ... is considered as the secure and accurate method ... of a particular individual because each individual,s signature ... results especially when dynamic signature of an individual ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... 26, 2015 --> ... 2016 - 2020 report analyzes that automating biobanking ... quality in long-term samples, minimizing manual errors, improving ... minimizes manual errors such as mislabeling or inaccurate ... it plays a vital role in blood fractionation, ...
(Date:11/25/2015)... , Nov. 25, 2015  Neurocrine Biosciences, Inc. ... Gorman , President and CEO of Neurocrine Biosciences, will ... Conference in New York . ... visit the website approximately 5 minutes prior to the ... replay of the presentation will be available on the ...
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman and ... early in their initial angel funding process. Now, they are paying it forward ... make early stage investments in the microbiome space. In this, they join ...
(Date:11/24/2015)... /CNW/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... the quarter ended September 30, 2015. Amounts, unless ... presented under International Financial Reporting Standards ("IFRS"). ... Andrew Rae , President & CEO of ... only value enriching for this clinical program, but ...
Breaking Biology Technology: