Navigation Links
LDL particle measurement by NMR recognized by ADA, ACC
Date:3/28/2008

Raleigh, NC, March 28, 2008 - The American Diabetes Association (ADA) and the American College of Cardiology (ACC) issued a consensus statement today that states the measurement of LDL particle number by nuclear magnetic resonance (NMR) is one of the more accurate ways to evaluate cardiometabolic risk (CMR). The study, published in the April issue of Diabetes Care, reinforces that LDL cholesterol may not be the best way to quantify a patients risk for cardiovascular disease (CVD).

Cardiometabolic Risk (CMR) is associated with Type 2 Diabetes and CVD obesity, insulin resistance, hyperglycemia and hypertension are risk factors that often cluster together. ApoB and LDL particle concentration appear to be more closely associated with these markers of CMR than LDL cholesterol or non-HDL cholesterol. Subsequently, lipoprotein abnormalities are commonly found in patients with CMR. According to the consensus statement, ApoB and LDL particle number by NMR appear to be more discriminating measures of the adequacy of LDL lowering therapies than are traditional LDL and HDL cholesterol measures.

"Several studies have shown that LDL cholesterol (LDL-C) poorly characterizes lipid abnormalities in patients with cardiometabolic risk," says Robert S. Rosenson, MD, Director of Lipoprotein Disorders and Clinical Atherosclerosis Research, University of Michigan School of Medicine and presenter at the consensus panel meeting. "Additionally, LDL-P concentrations, compared to LDL-C and non HDL-C, have been shown to be stronger predictors of cardiovascular risk."

The NMR LipoProfile test, developed by LipoScience, Inc., is the only test that quantifies LDL particle number (LDL-P) using Nuclear Magnetic Resonance. LDL particle information is used by clinicians to monitor the effect of lipid altering interventions, such as statins, in the management of a patients cardiovascular health by lowering LDL particle number (LDL-P).

Studies show that low concentrations of LDL particles are associated with fewer cardiovascular disease related events than equivalently low levels of LDL cholesterol; data most recently published from the Framingham Offspring study in December 2007.1

This consensus statement further demonstrates the critical role that the NMR LipoProfile test can play for the millions of people with diabetes or cardiovascular disease risk, says Rick Brajer, Chief Executive Officer and President, LipoScience, Inc. Measuring LDL particle number by NMR presents physicians and patients with the opportunity to better manage cardiometabolic risk.


'/>"/>

Contact: Maura Siefring
msiefring@dorland.com
267-765-3974
Dorland Global Public Relations
Source:Eurekalert

Related biology news :

1. Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
2. Carnegie Mellon scientist uses mass spectrometer to weigh virus particle, von Willebrand factor
3. New nanoparticle vaccine is more effective but less expensive
4. Nanoparticle exposures happen, says expert
5. Worldwide atmospheric measurements will determine the role of atmospheric fine particles
6. MIT: Remote-control nanoparticles deliver drugs directly into tumors
7. MIT sculpts 3-D particles with light
8. Technique controls nanoparticle size, makes large numbers
9. Tiny dust particles from Asian deserts common over western United States
10. Particle accelerator may reveal shape of alternate dimensions
11. Mesothelin engineered on virus-like particles provides treatment clues for pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2017)... 2017 At this year,s CeBIT Chancellor Dr. ... DERMALOG. The Chancellor came to the DERMALOG stand together with the Japanese ... CeBIT partner country. At the largest German biometrics company the two government ... and iris recognition as well as DERMALOGĀ“s multi-biometrics system.   ... ...
(Date:3/16/2017)... HANOVER, Germany , March 16, 2017 CeBIT 2017 - Against ... Continue Reading ... Used combined in one project, multi-biometric solutions ... ... Identification Systems) ...
(Date:3/9/2017)... , March 9, 2017 4Dx has ... World Lung Imaging Workshop at the University of Pennsylvania. ... invited to deliver the latest data to world leaders ... event brings together leaders at the forefront of the ... lung imaging. "The quality of the ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... ... March 28, 2017 , ... ... with the American Association for the Advancement of Science (AAAS), the world's ... partnership, ReadCube will enhance its high-impact scholarly collection across its cross-platform reference ...
(Date:3/28/2017)... ... March 28, 2017 , ... Benchworks announced that ... Philadelphia. The event was offered by the Chamber of Commerce for Greater Philadelphia ... groups and interaction with speakers who are leaders in their industries. Topics included ...
(Date:3/28/2017)... WASHINGTON , March 28, 2017  (AACR17, ... single-cell sequencing during the American Association for Cancer Research ... Center in Washington, D.C. , April ... gene expression of thousands of cells at the individual ... Experts on-hand at AACR to discuss expanded ...
(Date:3/28/2017)... , March 28, 2017 Dr. ... life sciences corporation Anpac Bio-Medical Science Company ... new, international record, processing and reporting over 40,000 ... Differentiation Analysis" (CDA) liquid biopsy tests. ... Prize Laureate Summit publications, Anpac Bio,s CDA medical ...
Breaking Biology Technology: