Navigation Links
LDL particle measurement by NMR recognized by ADA, ACC
Date:3/28/2008

Raleigh, NC, March 28, 2008 - The American Diabetes Association (ADA) and the American College of Cardiology (ACC) issued a consensus statement today that states the measurement of LDL particle number by nuclear magnetic resonance (NMR) is one of the more accurate ways to evaluate cardiometabolic risk (CMR). The study, published in the April issue of Diabetes Care, reinforces that LDL cholesterol may not be the best way to quantify a patients risk for cardiovascular disease (CVD).

Cardiometabolic Risk (CMR) is associated with Type 2 Diabetes and CVD obesity, insulin resistance, hyperglycemia and hypertension are risk factors that often cluster together. ApoB and LDL particle concentration appear to be more closely associated with these markers of CMR than LDL cholesterol or non-HDL cholesterol. Subsequently, lipoprotein abnormalities are commonly found in patients with CMR. According to the consensus statement, ApoB and LDL particle number by NMR appear to be more discriminating measures of the adequacy of LDL lowering therapies than are traditional LDL and HDL cholesterol measures.

"Several studies have shown that LDL cholesterol (LDL-C) poorly characterizes lipid abnormalities in patients with cardiometabolic risk," says Robert S. Rosenson, MD, Director of Lipoprotein Disorders and Clinical Atherosclerosis Research, University of Michigan School of Medicine and presenter at the consensus panel meeting. "Additionally, LDL-P concentrations, compared to LDL-C and non HDL-C, have been shown to be stronger predictors of cardiovascular risk."

The NMR LipoProfile test, developed by LipoScience, Inc., is the only test that quantifies LDL particle number (LDL-P) using Nuclear Magnetic Resonance. LDL particle information is used by clinicians to monitor the effect of lipid altering interventions, such as statins, in the management of a patients cardiovascular health by lowering LDL particle number (LDL-P).

Studies show that low concentrations of LDL particles are associated with fewer cardiovascular disease related events than equivalently low levels of LDL cholesterol; data most recently published from the Framingham Offspring study in December 2007.1

This consensus statement further demonstrates the critical role that the NMR LipoProfile test can play for the millions of people with diabetes or cardiovascular disease risk, says Rick Brajer, Chief Executive Officer and President, LipoScience, Inc. Measuring LDL particle number by NMR presents physicians and patients with the opportunity to better manage cardiometabolic risk.


'/>"/>

Contact: Maura Siefring
msiefring@dorland.com
267-765-3974
Dorland Global Public Relations
Source:Eurekalert

Related biology news :

1. Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
2. Carnegie Mellon scientist uses mass spectrometer to weigh virus particle, von Willebrand factor
3. New nanoparticle vaccine is more effective but less expensive
4. Nanoparticle exposures happen, says expert
5. Worldwide atmospheric measurements will determine the role of atmospheric fine particles
6. MIT: Remote-control nanoparticles deliver drugs directly into tumors
7. MIT sculpts 3-D particles with light
8. Technique controls nanoparticle size, makes large numbers
9. Tiny dust particles from Asian deserts common over western United States
10. Particle accelerator may reveal shape of alternate dimensions
11. Mesothelin engineered on virus-like particles provides treatment clues for pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2016)... 21, 2016   Neurotechnology , a provider ... today announced that the MegaMatcher On Card fingerprint ... for the NIST Minutiae Interoperability Exchange (MINEX) ... mandatory steps of the evaluation protocol. ... test of fingerprint templates used to establish compliance ...
(Date:11/17/2016)... 17, 2016  AIC announces that it has just released a new white paper ... high-performance scale-out plus high speed data transfer storage solutions. Photo - ... ... ... Setting up a high performance computing or HPC ...
(Date:11/15/2016)... Research and Markets has announced the addition of the ... their offering. ... The global bioinformatics market ... 6.21 Billion in 2016, growing at a CAGR of 21.1% during ... is driven by the growing demand for nucleic acid and protein ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... 7, 2016  Vyriad Inc. announced today the appointment ... Board of Directors. "We are delighted to ... business and develop our oncolytic viruses as the next ... Stephen Russell , MD, PhD, CEO of Vyriad. "Al ... vision and passion for making a difference for cancer ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... resource recovery solutions for industrial facilities, today announced that one of the nation’s ... to use Cambrian’s novel water-energy purchase agreement (WEPA). Under the WEPA, a first ...
(Date:12/6/2016)... Texas , Dec. 6, 2016 The ... for its adoption of arnica ( Arnica montana ... support to ABC,s HerbMedPro database, a ... important scientific and clinical research data on the ... popular herbs. Naturopathica, a wellness company ...
(Date:12/6/2016)... (PRWEB) , ... December 06, 2016 , ... ... of custom industrial automation and IT solutions, today announced the company has successfully ... reliably delivered professionally executed automation and control systems integration services to leading companies ...
Breaking Biology Technology: