Navigation Links
Kinked nanopores slow DNA passage for easier sequencing
Date:7/30/2010
hannels. Researchers hope to emulate these behaviors by creating more robust synthetic materials more readily integrated into practical devices.
Current scientific procedures align the formation of nominally cylindrical or conical pores at right angles to a membrane surface. These are less capable of significantly slowing the passage of DNA than the kinked nanopores.
"We had a pretty simple idea," Brinker says. "We use the self-assembly approaches we pioneered to make ultrathin membranes with ordered arrays of about 3-nanometer diameter pores. We then further tune the pore size via an atomic-layer deposition process we invented. This allows us to control the pore diameter and surface chemistry at the subnanometer scale. Compared to other solid state nanopores developed to date, our system combines finer control of pore size with the development of a kinked pore pathway. In combination, these allow slowing down the DNA velocity."
The work is supported by the Air Force Office of Scientific Research, the Department of Energy's Basic Energy Sciences and Sandia's Laboratory Directed Research and Development office.
'/>"/>
| Contact: neal singer nsinger@sandia.gov 505-845-7078 DOE/Sandia National Laboratories Source:Eurekalert |
Related biology news :
1. First step toward electronic DNA sequencing: Translocation through graphene nanopores
2. NIST team advances in translating language of nanopores
3. Lollipops and ice fishing: Molecular rulers used to probe nanopores
4. Polymer passage takes time
5. Seabed biodiversity of the Straits of Magellan and Drake Passage
6. Technology improves salmon passage at hydropower dams
7. Seemingly suicidal stunt is normal rite of passage for immune cells
8. New retrieval method makes studying cancer proteins easier
9. Pesticides -- easier detection of pollution and impact in rivers
10. Grouping muscles to make controlling limbs easier
11. A little java makes it easier to jive, researcher says
Post Your Comments:
(Date:5/22/2013)... conclude that the 20 percent reduction in lung ... chest X-ray (CXR) screening previously reported in the ... centers in the United States. , Philadelphia, PAPhysicians ... about the benefits and risks of LDCT lung ... New England Journal of Medicine of the ...
(Date:5/22/2013)... must join together in a major new effort to ... in providing Earth,s people with clean water that looms ... a comment article in the current edition of ... the American Chemical Society (ACS), the world,s largest scientific ... Ph.D., and Jerald L. Schnoor, Ph.D., explain that shortages ...
(Date:5/22/2013)... The discovery of potential environmental and human health ... batteries each year has led scientists to recommend ... reuse of lithium-ion (Li-ion) battery materials. That,s the ... journal Environmental Science & Technology . , ... Li-ion batteries have become mainstays for powering everything ...
Breaking Biology News(10 mins):NLST: CT detects twice as many lung cancers as X-ray at initial screening exam 2NLST: CT detects twice as many lung cancers as X-ray at initial screening exam 3... , Research collaboration between India and Germany has intensified. ... the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), during a ... research institutes in New Delhi on Nov. 3 and ... countries has reached a new dimension," said the DFG ...
... prey are conservationally at risk, it can be difficult to find ... , Such is the case for a particular population of orcas ... the coast of Washington State and British Columbia, but a new ... what must be done to conserve both. The study, reported ...
... research team at the National Institute of Standards and Technology ... that may play a critical role in the reproduction of ... the "fish flu." A scourge in fish farms with a ... found in wild salmon in the Pacific Northwest for the ...
Cached Biology News:Scientific collaboration between India and Germany reaches new dimension 2Fish flu: Genetics approach may lead to treatment 2(Date:5/24/2013)... 2013 Quincy Bioscience, a leading ... of calcium-binding proteins to support healthy living, is ... study of apoaequorin in Food and ... the British Industrial Biological Research Association. , ... potential adverse effects, if any, of apoaequorin, in ...
(Date:5/23/2013)... 2013 Can economic incentives such as ... members of the public to increase their donations of ... Hopkins Carey Business School Assistant Professor Mario Macis ... a large body of recent research that supports their ... 2013, issue of Science that the World Health Organization ...
(Date:5/23/2013)... The maker community is a contemporary ... They focus on learning practical skills while applying them ... bringing their ideas to life via crowdfunding. A subgroup ... making projects using biology. Glowing Plant has worked for ... them glow with bioluminescence genes, and has now pursued ...
(Date:5/23/2013)... , May 23, 2013 BioTrends ... and advisory firms for specialized biopharmaceutical issues, finds ... and infectious disease specialists reported that in the ... (e.g., intentionally delaying treatment) in anticipation of the ... six months ago, when only 6 percent reported ...
Breaking Biology Technology:Safety Assessment Study of Apoaequorin Published in Food and Chemical Toxicology 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3Glowing Plant Releases Maker Kit, Enabling Anyone to Make a Glowing Plant at Home 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3[0] Safety Assessment Study of Apoaequorin Published in Food and Chemical Toxicology[0] Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science[0] Glowing Plant Releases Maker Kit, Enabling Anyone to Make a Glowing Plant at Home[0] The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments
... signed into law Senate Bill 338, which is designed ... in the way of University of Wisconsin researchers. , ... turn research ideas into potential business opportunities. He said ... faculty and staff try to start businesses based on ...
... San Francisco or Boston, and youre on the verge of investing ... right: The management team is in place, the business plan is ... a lawyer steps into the room, clears her throat and asks ... not write that check, she says, until you learn more about ...
... - Are state government information technology consolidation projects ... Miszewski, the CIO for the State of Wisconsin, has ... are not unusual for large state projects. He has ... government CIOs, but are cost overruns, implementation delays, and ...
Cached Biology Technology:Why repealing the shareholder wage lien law makes sense 2Why repealing the shareholder wage lien law makes sense 3State IT failures are not inevitable 2State IT failures are not inevitable 3State IT failures are not inevitable 4State IT failures are not inevitable 5ma. plate stack height 70mm...
... MBS Satellite Thermal Cycler (MBS) ... solution for medium to high ... combines the latest in satellite ... and PC control, resulting in ...
45° Fixed Angle Rotor for use in the IEC Centra CL2, Centra CL3/CL3R, HN-SII, and the Centra-MP4/MP4R....
Glycerokinase; from Bacillus stearothermophilus...
Biology Products:| Copyright © 2003-2012 Bio-Medicine. All rights reserved. ABOUT | CONTACT US | DISCLAIMER | PRIVACY POLICY | TERMS AND CONDITIONS |  |