Navigation Links
Key to burning fat faster discovered
Date:8/22/2012

m more efficient would have required a major reconstruction. In some cases so difficult that it is on the order of transforming a handsaw into a chainsaw, says the chemist, Assistant Professor Nikos Hatzakis, who was deeply involved in the scrutiny of the enzymes.

"Changing the fundamental shape of a tool is always difficult. Whether it's saw or an enzyme. But working longer hours with the same tool is infinitely easier. What we've achieved, is to make enzymes work longer hours", explains Hatzakis.

Scrutiny on the Nanoscale

Observing that enzymes even have an on-off switch may sound easy, but first the Bio Nano- team had to devise a way to study individual enzyme molecules. These are so small, that there are trillions in just a drop of water. So measuring the work of only one enzyme could be compared to looking down from the moon to detect each time a carpenter in a building in Copenhagen swings his hammer.

Light emitting fat

To perform their studies the researchers chose a fat degrading lipase enzyme model system in collaboration with Danish industrial enzyme producer Novozymes.

They used "fat" that would emit light each time the enzyme took a bite. This way they could monitor each and every catalytic cycle or single movement of work. To ensure realism the enzymes were placed on an artificial cell wall. An "in vivo like membrane system", says Stamou.

"Natural enzymes live in cells. Looking at them in a non native environment, would tell us as much as looking at a carpenter working in outer space wearing a space suit would tell us about builders", explains Dimitrios Stamou and concludes:

"Now that we have understood how to switch enzymes on and off we could use this knowledge in the future both for curing diseases but also to design novel enzymes for industrial applications".


'/>"/>
Contact: Jes Andersen
jean@science.ku.dk
45-30-50-65-82
University of Copenhagen
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Hyenas that think outside the box solve problems faster
2. Searching genomic data faster
3. Palladium-gold nanoparticles clean TCE a billion times faster than iron filings
4. Exome sequencing gives cheaper, faster diagnosis in heterogeneous disease
5. Faster, cheaper gas and liquid separation using custom designed and built mesoscopic structures
6. What does a tree growing faster than its neighbor look like from outer space?
7. Athletic frogs have faster-changing genomes
8. Tiny electrical sensors could signal faster MRSA diagnosis
9. From scourge to saint: E. coli bacteria becomes a factory - to make cheaper, faster pharmaceuticals
10. Oceans acidifying faster today than in past 300 million years
11. 2 new owls discovered in the Philippines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Key to burning fat faster discovered
(Date:4/20/2015)... Calif. , April 20, 2015 Huntington ... Gabriel Valley to implant a new miniaturized, wireless monitoring ... System is the first and only FDA-approved heart failure ... hospital admissions when used by physicians to manage heart ... sensor that is implanted in the pulmonary artery (PA) ...
(Date:4/13/2015)... According to a recently ... & Opportunities, 2020", the global biometrics market is ... till 2020. The biometrics market is garnering attention ... review of biometric management systems. The constant development ... greater efficiency, are resulting in increasing installation of ...
(Date:4/6/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... on the growing mobile commerce market, announced today ... MINIATURE, MULTI-PURPOSE ANTENNA METHOD AND SYSTEM FOR ... introduces a new revolutionary method and system to ... of miniature antenna modules for multiple purposes including ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4
... to display the earliest signs of Parkinson,s disease using the ... the disease. The mouse model, which expresses the same ... of constipation and other gastrointestinal problems that are a common ... result, researchers say, these animals could serve as a means ...
... Bethesda, MarylandThe American Association of Anatomist,s (AAA) presented its ... Meeting in Anaheim. This year,s honors went to: ... Dept. of Cell and Developmental Biology at SUNY Upstate ... the 2010 Henry Gray/ Lippincott Williams & Wilkins Scientific ...
... in Spanish . ANN ARBOR, Mich. ... treat breast cancer by targeting cancer stem cells -- the ... according to a new study from researchers at the University ... a component of broccoli and broccoli sprouts, in both mice ...
Cached Biology News:UCSF transgenic mouse mimics Parkinson's earliest symptoms 2UCSF transgenic mouse mimics Parkinson's earliest symptoms 3Broccoli component limits breast cancer stem cells, U-M study finds 2
(Date:5/21/2015)... 2015 Veolia’s environmental monitoring technology ... American distribution agreement with VWR to distribute TECTA™ ... more than 160 years of experience, VWR, a ... laboratory and production facilities, has cultivated a value ... services to enable science. Endetec’s TECTA™ B16, ...
(Date:5/20/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/x4b7kw/top_technologies ... Technologies in HW_Technical Insights" report to their offering. ... technology trends in the Health and Wellness sector and ... have an impact in the year 2015. The research ... 10 health and wellness technologies that are anticipated to ...
(Date:5/20/2015)... MECHANICSBURG, Pa. , May 20, 2015 /PRNewswire/ ... announced that the Federal Trade Commission granted early ... (HSR) Antitrust Improvements Act of 1976, as amended, ... by MJ Acquisition Corporation, a joint venture that ... XII, L.P. As previously announced, MJ ...
(Date:5/20/2015)... Agricultural firm H.J. Baker & Bro., Inc. today ... Since the purchase of Tiger Industries and Tiger-Sunbelt ... H.J. Baker has leveraged the innovation of the Tiger-Sul ... of product offerings and solutions expertise. The deal brought ... of Tiger-Sul, transforming the company into a leading enterprise ...
Breaking Biology Technology:Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Top Technologies in the Health and Wellness Industry 2015 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 3
... 2008 MaxCyte, Inc., a,clinical-stage therapeutics company ... systems, announces that Anthony Recupero, Ph.D.,Vice President ... Tuesday,April 8, 2008, at 2:00PM at the ... Recupero,s presentation will discuss the development of,engineered ...
... Bluestar Silicones,introduces a new range of Silbione(R) brand ... market that provide a unique combination,of strong physical ... durometers., These new low durometer products incorporate ... to 70- ShA LSR product,line, including easy processing, ...
... Center for ... Critical Path Immunology -, SAN FRANCISCO, April 7, ... B. Kantor, Ph.D. has,joined the company in the position of Chief ... Officer. Prior to,joining ITI, Dr. Kantor served as Executive Director of ...
Cached Biology Technology:Bluestar Silicones Introduces Three New Soft and Durable Liquid Silicone Rubber Products 2Immune Tolerance Institute Appoints Aaron B. Kantor Ph.D. Chief Scientific Officer 2Immune Tolerance Institute Appoints Aaron B. Kantor Ph.D. Chief Scientific Officer 3Immune Tolerance Institute Appoints Aaron B. Kantor Ph.D. Chief Scientific Officer 4
Donor Horse Serum US Origin...
Mouse Aminopeptidase P2/XPNPEP2 Biotinylated Aff Pur PAb Keywords: AminopeptidaseP2, Metalloproteinase, Metalloprotease, X-Prolyl Aminopeptidase 2, X-Pro Aminopeptidase 2, Membrane-bound Prote...
AGAROSE PREP, 50G, 1 EA. Category: Genephor Precast Gels....
... from egg white. The extinction coefficient , ... 10 mM phosphate-buffered saline, pH 7.4, ... azide and 50% glycerol. Avidin (from egg white) ... purified by molecular sieving and is ...
Biology Products: