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Key driver of metastasis identified
Date:10/30/2011

f scissors on the outside of the macrophages that empowers the macrophages with the ability to chew their way through tissues and enter the tumor site where they release substances that stimulate cancer cell growth and metastatic evolution," said Waisman.

He said the next step is to figure out exactly how S100A10 functions as a molecular scissor and also to identify pharmaceutical agents that can block the action of S100A10, thereby preventing the movement of macrophages to the tumor site. By understanding exactly how S100A10 works at the molecular level, it may even be possible to design agents which block its activity.


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Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

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