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KaloBios to Present KB004 Interim Phase 1 Clinical Data in Hematologic Malignancies at ASH
Date:11/7/2013

SOUTH SAN FRANCISCO, Calif., Nov. 7, 2013 /PRNewswire/ -- KaloBios Pharmaceuticals, Inc. (Nasdaq: KBIO) today announced that data from its ongoing Phase 1 trial of KB004, an anti-EphA3 monoclonal antibody (mAb), will be presented at a poster session at the 55th American Society of Hematology (ASH) Annual Meeting and Exhibition. The Phase 1 trial of KB004 is a multi-center, dose-escalation study evaluating KB004 in patients with advanced hematologic malignancies. The presentation will include data describing the safety, pharmacokinetics and clinical activity of KB004. The ASH meeting is being held in New Orleans, Louisiana from December 7 – 10, 2013.

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"This presentation will describe the safety profile observed in our ongoing Phase 1 trial of KB004, as well as reductions in markers of disease activity, peripheral blood blast percentage and marrow blast percentage," stated Dr. Nestor A. Molfino, Chief Medical Officer at KaloBios.  "We believe these early data support the potential of KB004 in EphA3 positive hematologic malignancies, and we are targeting enrolling the first patient in the Phase 2 portion of the study of this antibody by the end of 2013."

Poster Presentation Details

  • Title: A Phase I study of KB004, a novel non-fucosylated humaneered® antibody, targeted against the receptor tyrosine kinase EphA3, in advanced hematologic malignancies
  • Date: Monday, December 7,, 2013
  • Presentation Time: 6:00 p.m. – 8:00 p.m. 
  • Presenter: Jeffrey Lancet, MD, Medical Oncology, H. Lee Moffitt Cancer Center and Research Ins
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SOURCE KaloBios Pharmaceuticals, Inc.
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