Navigation Links
KIT researchers develop artificial bone marrow
Date:1/10/2014

This news release is available in German.

Artificial bone marrow may be used to reproduce hematopoietic stem cells. A prototype has now been developed by scientists of KIT, the Max Planck Institute for Intelligent Systems, Stuttgart, and Tbingen University. The porous structure possesses essential properties of natural bone marrow and can be used for the reproduction of stem cells at the laboratory. This might facilitate the treatment of leukemia in a few years. The researchers are now presenting their work in the "Biomaterials" journal (DOI: 10.1016/j.biomaterials.2013.10.038).

Blood cells, such as erythrocytes or immune cells, are continuously replaced by new ones supplied by hematopoietic stem cells located in a specialized niche of the bone marrow. Hematopoietic stem cells can be used for the treatment of blood diseases, such as leukemia. The affected cells of the patient are replaced by healthy hematopoietic stem cells of an eligible donor.

However, not every leukemia patient can be treated in this way, as the number of appropriate transplants is not sufficient. This problem might be solved by the reproduction of hematopoietic stem cells. So far, this has been impossible, as these cells retain their stem cell properties in their natural environment only, i.e. in their niche of the bone marrow. Outside of this niche, the properties are modified. Stem cell reproduction therefore requires an environment similar to the stem cell niche in the bone marrow.

The stem cell niche is a complex microscopic environment having specific properties. The relevant areas in the bone are highly porous and similar to a sponge. This three-dimensional environment does not only accommodate bone cells and hematopoietic stem cells but also various other cell types w
'/>"/>

Contact: Monika Landgraf
presse@kit.edu
49-721-608-47414
Helmholtz Association
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers pursuing arthritis protein
2. Researchers discover a tumor suppressor gene in a very aggressive lung cancer
3. Researchers unveil rich world of fish biofluorescence
4. Researchers propose alternative way to allocate science funding
5. New organization brings together top researchers to sequence the genomes of invertebrates
6. Plan to delist gray wolf endangers other threatened species, researchers find
7. Researchers say fructose does not impact emerging indicator for cardiovascular disease
8. Researchers complete a milestone in defining the genetic basis of rheumatoid arthritis
9. Researchers create largest evolutionary timetree of land plants to investigate traits that permit survival in cold climates
10. Penn researchers grow liquid crystal flowers that can be used as lenses
11. UT Southwestern neuroscience researchers identify gene involved in response to cocaine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
KIT researchers develop artificial bone marrow
(Date:7/11/2014)... Mineral Research awarded Michael F. Holick, PhD, MD, of ... Louis V. Avioli Award. Holick, a professor of medicine, ... revolutionizing the understanding of vitamin D and its role ... member of the American Society for Bone and Mineral ... basic research. It is named for ASBMR,s first president ...
(Date:7/11/2014)... 10, 2014---A team of researchers from The Chinese University ... a gene of wild soybean linked to salt tolerance, ... in saline soil. This study published online in ... novel genomic information for crop improvement. , Soybean is ... and human selection, cultivated soybeans have less genetic diversities ...
(Date:7/11/2014)... July 11, 2014 Researchers have pioneered ... images. The new technology, called Virtual Finger, allows ... structures like neurons and synapses using the flat ... technology makes 3D imaging studies orders of magnitude ... an unprecedented level across many areas of experimental ...
Breaking Biology News(10 mins):BUSM's Michael F. Holick receives American Society for Bone and Mineral Research award 2BGI reports a novel gene for salt tolerance found in wild soybean 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... known as a keystone species, filling such an important ... can collapse. Scientists are finding, however, that sea otters ... communities and alter the behavior of another top predator: ... towering kelp can reach heights of 250 feet and ...
... To help improve the success of oyster restoration efforts ... Environmental Science researcher Dr. Elizabeth North is leading a ... determine when oysters spawn and where their larvae go ... by a $750,000 competitive grant from the National Science ...
... DNA testing for hereditary breast cancer are associated with ... predictor of whether women had been able to leave ... the October issue of Genetics in Medicine , ... (ACMG). The journal is published by Lippincott Williams ...
Cached Biology News:Decline in Alaskan sea otters affects bald eagles' diet 2Decline in Alaskan sea otters affects bald eagles' diet 3Study looks at psychological impact of gene test for breast cancer 2Study looks at psychological impact of gene test for breast cancer 3
(Date:7/10/2014)... Terascala, the industry leader in HPC management ... vice president of product management for Flexera Software, has ... Terascala’s software when combined with leading compute and storage ... and most reliable solutions for processing big data. , ... and broaden its product portfolio. His leadership in startups ...
(Date:7/10/2014)... CA (PRWEB) July 10, 2014 OMICS ... Bioanalytical techniques during 18-20 August, 2014 at Double Tree ... review the recent developments in Analytical & Bioanalytical research ... globe. , Speaking on this occasion, Dr. Srinubabu Gedela, ... Analytica Acta conference is a remarkable one in bringing ...
(Date:7/10/2014)... , July 10, 2014  Franciscan St. ... of capnography for respiratory monitoring outside the ... healthcare leaders in embracing state-of-the-art patient safety ... patients are breathing and can alert medical ... measuring the amount of carbon dioxide the ...
(Date:7/10/2014)... Utah , July 10, 2014 /PRNewswire-iReach/ ... annotation and interpretation, today announced an agreement ... (NGS) analytics for Lineagen,s NextStep Dx ... of neurodevelopmental and neurological disorders, currently offers ... microarray (CMA) testing service used by healthcare ...
Breaking Biology Technology:Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4
... Powell, former,President and Chief Operating Officer of SurModics ... Corporation., Under Powell,s guidance, SurModics developed medical ... commercialize products.,Powell joined SurModics in 1987 as the ... company,s transition from a diagnostics kit,manufacturer to a ...
... July 29 SCOLR Pharma, Inc.,(Amex: DDD ) ... on Thursday, August 7, 2008, at 8:30 a.m. Eastern. ... host a conference call at 11:30,a.m. Eastern, to discuss ... participate in the,conference call by dialing +1 888 680 ...
... VOLC ), a leading manufacturer and developer ... Coherence,Tomography (OCT) products designed to enhance the diagnosis ... announced that it will,report its operating results for ... 2008 on Tuesday, August 5., The company ...
Cached Biology Technology:James C. Powell Joins Nerites Board of Directors 2SCOLR Pharma, Inc. Schedules Second Quarter 2008 Financial Results Conference Call for August 7, 2008 at 11:30 A.M. Eastern 2Volcano Corporation Schedules Second Quarter Conference Call, Webcast 2
Rabbit anti Xanthine Oxidase Xanthine Oxidase, Bovine Buttermilk...
... Stain for Mass Spectrometry Applications ,In ... (MS) has emerged as a powerful protein ... 2-D gels is now an important intermediate ... leads ultimately to identification of specific proteins ...
... M-PER Mammalian Protein Extraction Reagent ... lysis solution that means no ... no sonication! With M-PER Reagent, ... five minutes at room temperature, ...
... Optimization Kits with ammonium sulfate are compatible ... such as Tfl, Tth, and Pfu DNA ... of PCR systems in one experiment by ... primers into the PreMixes supplied with the ...
Biology Products: