Navigation Links
K-State researchers find gene-silencing nanoparticles may put end to pesky summer pest
Date:7/19/2010

MANHATTAN, Kan. -- Summer just wouldn't be complete without mosquitoes nipping at exposed skin. Or would it?

Research conducted by a Kansas State University team may help solve a problem that scientists and pest controllers have been itching to for years.

Kun Yan Zhu, professor of entomology, and teammates Xin Zhang, graduate student in entomology from China, and Jianzhen Zhang, a visiting scientist from Shanxi University, China, investigated using nanoparticles to deliver double-stranded ribonucleic acid, dsRNA -- a molecule capable of specifically triggering gene silencing -- into mosquito larvae through their food. By silencing particular genes, Zhu said the dsRNA may kill the developing mosquitoes or make them more susceptible to pesticides.

Gene silencing triggered by dsRNA or small interfering RNA, siRNA, is known as RNA interference, or RNAi.

"RNAi is a specific and effective approach for loss of function studies in virtually all eukaryotic organisms," Zhu said. Eukaryotic organisms have cells that contain a nucleus within which genetic material is carried and can therefore be manipulated. Almost all animals, plants and fungi are eukaryotes.

Once RNAi is triggered, it destroys the messenger RNA, or mRNA, of a particular gene. This prevents the translation of the gene into its product, silencing it. In the case of Zhu's research, RNAi was used to silence genes responsible for the production of chitin, the principle constituent of the exoskeleton in insects, crustaceans and arachnids.

"Since our RNAi is focused on chitin synthesis, the dsRNA that is delivered into the mosquito larvae can basically block the production of chitin," Zhu said.

Though the silencing is not yet 100 percent effective in their study, Zhu said it does leave the mosquito's body with less ability to combat insecticides, which must penetrate the mosquito's exoskeleton. If the gene, called chitin synthase, could be completel
'/>"/>

Contact: Kun Yan Zhu
kzhu@k-state.edu
785-532-4721
Kansas State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. NIH grants K-State researcher nearly $1.5 million to study antibiotic-resistant bacteria
2. K-State professor using NSF award to study the impact of nitrogen deposition on global change
3. K-State scientist to receive $1 million CAREER award
4. K-State plant pathology professor awarded international professorship for Latin America
5. K-State program will give young professionals skills to protect water resources
6. Ph.D. student in K-State plant pathology selected for international fellowship
7. K-State receives more than $780,000 to fund graduate students studying ecology, evolution, genomics
8. K-State geographer working to clarify what sustainability really means to rural decision-makers
9. Cybernetwork to help K-State researchers study tallgrass prairie, respond to global warming
10. K-State Pollution Prevention Institutes intern program named best
11. K-States plant pathology head named fellow of Phytopathology Society
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... LAS VEGAS , Dec. 18, 2014   ... platform built for the post-password and Internet of Things ... additional seed funding. The venture round was led by ... Pantera Capital, Rimrock Venture Partners, VegasTechFund, and others.  LaunchKey ... the new funding to expand its team and bring ...
(Date:12/17/2014)... Dec. 16, 2014 Research and Markets ... of the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major ... demand for medical sensors in biomedical applications. Chemical ... quick and correct diagnosis during surgical procedures. The ...
(Date:12/11/2014)... -- That blood pressure plays a role in human health has ... term for high blood pressure – was first described as ... that,s used in measuring blood pressure was invented in 1896. ... hypertension, its triggers and its effects. In fact, recent findings ... best ways to treat it. For example, a ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... may be useful in fighting malaria, researchers report in a ... the drug readily crosses into the red blood cells of ... at very low concentrations with no observed toxicity to the ... the National Academy of Sciences . The researchers found ...
... Stanford, CA -- The major difference between plant and ... energy into chemical energy. When light isn,t available, energy ... as it is in animal and some bacterial cells. ... the chloroplasts for photosynthesis and the mitochondria for sugar ...
... Humans are frequently blamed for deforestation and the destruction of ... around the world that have learned to manage and conserve ... Peruvian Amazon and the Tibetans of the Himalayas are two ... even in the face of rapid environmental changes. Over the ...
Cached Biology News:Modified bone drug kills malaria parasite in mice 2Amoeba may offer key clue to photosynthetic evolution 2Amoeba may offer key clue to photosynthetic evolution 3Indigenous peoples at forefront of climate change offer lessons on plant biodiversity 2Indigenous peoples at forefront of climate change offer lessons on plant biodiversity 3Indigenous peoples at forefront of climate change offer lessons on plant biodiversity 4
(Date:12/19/2014)... 2014 Today, TiFiber, Inc. ... production facility and future company headquarters in Fort ... new materials that safely and effectively control dangerous ... of its historic, strong support for manufacturing, but ... leading edge, technology-based companies such as TiFiber. ...
(Date:12/19/2014)... Biddeford, ME (PRWEB) December 18, 2014 ... founding director of the Center for Excellence in the ... of New England, has been selected as a member ... He is the first neuroscientist from Maine to receive ... a nonprofit organization supported entirely by the Dana Foundation. ...
(Date:12/19/2014)... (PRWEB) December 18, 2014 iLab Solutions, ... the appointment of Siri Bryant as the new Director ... Director of Core Implementations. These two new leadership positions ... customer service by ensuring that iLab continues to meet ... the last four years, iLab has been deployed at ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 The ... to the rising ageing population and technological innovations ... and nutraceutical industries are catalysing the growth of ... @ http://www.marketsandmarkets.com/Market-Reports/empty-capsules-market-218018190.html , Scope of Report ... as well as new entrants/smaller firms to gauge ...
Breaking Biology Technology:Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4
... (Nasdaq: BIOM ),(TSX: BRA) ("Biomira", the "Company") ... plan of arrangement under which the Company,will move ... to Oncothyreon Inc.,("Oncothyreon"). The approval came at a ... the plan of arrangement, which remains,subject to court ...
... Dec. 4 An independent panel of scientists,has ... Safe) status for its patented probiotic, GanedenBC30 (Bacillus ... research studies and,toxicology data, the panel concluded that ... food products. According to the FDA, self-affirmed GRAS,status ...
... Maxygen, Inc.,(Nasdaq: MAXY ), a biotechnology ... announced today the license of its proprietary,dengue virus ... of,the sanofi-aventis Group., Under the terms of ... portfolio of preclinical dengue antigens for development and,worldwide ...
Cached Biology Technology:Biomira Shareholders Approve Move to U.S. 2Biomira Shareholders Approve Move to U.S. 3Ganeden Biotech Obtains Self-Affirmed GRAS Status for Probiotic Ingredient, GanedenBC30 (Bacillus coagulans GBI-30, 6086) 2Maxygen Licenses Dengue Vaccine Technology to sanofi pasteur 2Maxygen Licenses Dengue Vaccine Technology to sanofi pasteur 3
HSD17B3 Immunogen: HSD17B3 (NP_000188, 29 a.a. ~ 120 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Rad51, N-terminal...
Phospho-mu-Opioid Receptor (Ser375) Antibody...
Rabbit polyclonal to WWOX8 ( Abpromise for all tested applications). entrezGeneID: 51741 SwissProtID: Q9NZC7-8...
Biology Products: