Navigation Links
K-State lab gives researchers the tools to study porcine circovirus associated diseases

Porcine circovirus associated diseases cost pig producers around the world hundreds of millions of dollars each year.

That's why Kansas State University virologists Dick Hesse and Bob Rowland have been working to create new vaccines to tackle such complex diseases.

"Circovirus and its associated diseases continue to emerge around the world," Hesse said. "Both porcine reproductive and respiratory syndrome and circovirus are a worldwide problem and they continue to evolve."

Hesse and Rowland say that because these viruses continue to adapt, the quick development of effective countermeasures like vaccines is critical, as is having the facilities in which to test the vaccine in a timely fashion.

Later this month, they will begin testing their next-generation vaccine against circovirus at K-State's Biosecurity Research Institute, or BRI, in Pat Roberts Hall.

The vaccination experiment they are preparing is complex and will involve simultaneously testing several groups with porcine circovirus, porcine reproductive and respiratory syndrome, or a combination of the two. Testing vaccine efficacy against viral combinations will be crucial because that's when the most severe forms of disease occur, according to the researchers.

For the purposes of experimentation, keeping each of the groups separate also will be crucial. The BRI is designed so that research on a multitude of agents can take place in rooms adjacent to each other so there is no cross contamination.

"The viruses that we are using have some very unique properties that make containment difficult. In the field, part of the challenge presented by circovirus is that it is easily spread," Rowland said. "We have a lot of experimental groups and under normal circumstances when you are working with infectious disease, it's difficult to prevent cross contamination."

Without the BRI, Hesse and Rowland would have to go elsewhere to conduct an experiment of this scale. They said the ability to do the research at the BRI will mean that the remedies for disease can be available to producers sooner.

"The BRI has some unique capabilities and opportunities for our research," Rowland said "As a result of having access to these facilities we can accelerate our work and infectious disease research at K-State."

"This experiment is setting the stage for the future," Hesse said.

K-State's Biosecurity Research Institute is a biosafety level 3 and biosafety level 3 agriculture research facility. Research at the BRI will help scientists develop a deeper understanding of the pathogens and pests that threaten the U.S. animal- and plant-based agricultural systems so that vaccines and other countermeasures may be proactively developed.

Research at the BRI will eventually include pathogens that directly impact humans, such as brucella and various influenza strains, including H1N1.

Though circovirus and porcine reproductive and respiratory syndrome aren't human pathogens, this research will help BRI officials refine their protocols and procedures.

"The development of appropriate practices, procedures and policies are essential to performing quality research at the BRI," said Scott Rusk, director of Pat Roberts Hall. "Each incoming project will have unique requirements. This collaborative process will help us ensure the safety of personnel and promote high-quality research practices."

The existence of the BRI and the nexus of scientific expertise on animal health and disease at K-State were among the primary reasons the U.S. Department of Homeland Security chose to build the National Bio and Agro-Defense Facility in Manhattan.


Contact: Richard Hesse
Kansas State University

Related biology news :

1. Stimulus funding helps K-State biochemist study eyes lens in diabetes, galactosemia patients
2. K-State researchers say after-school programs should promote activity, healthy nutrition
3. K-State researcher, collaborators study virulence of pandemic H1N1 virus
4. K-State plant pathologists develop online teaching modules used globally
5. Researchers from around the globe coming to K-State June 21 for workshop on Fusarium fungus
6. K-State host to workshop on rapid methods to detect microorganisms in food
7. K-State researcher finds 1918 flu resulted in current lineage of H1N1 swine influenza viruses
8. K-State using Second Life island to help high school students learn earth science
9. K-State researchers work with university in Ghana to create biofuels from native tree seeds
10. K-State researchers help Epitopix license the United States first E. coli O157 vaccine for cattle
11. K-State biologist collaborating with researchers in Africa on grassland sustainability, biodiversity
Post Your Comments:
(Date:5/3/2016)... Lithuania , May 3, 2016  Neurotechnology, ... released the MegaMatcher Automated Biometric Identification System ... of large-scale multi-biometric projects. MegaMatcher ABIS can process ... accuracy using any combination of fingerprint, face or ... MegaMatcher SDK and MegaMatcher Accelerator ...
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
(Date:4/14/2016)... April 14, 2016 BioCatch ... Detection, today announced the appointment of Eyal Goldwerger ... role. Goldwerger,s leadership appointment comes at a ... of the deployment of its platform at several of ... technology, which discerns unique cognitive and physiological factors, is ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample tracking software company, ... Crime Laboratory, has joined STACS DNA as a Field Application Specialist. , “I ... President and COO of STACS DNA. “In further expanding our capacity as a scientific ...
(Date:6/23/2016)... Calif. , June 23, 2016  Blueprint Bio, ... biological discoveries to the medical community, has closed its ... Matthew Nunez . "We have received ... with the capital we need to meet our current ... essentially provide us the runway to complete validation on ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... at the Pennsylvania Convention Center and will showcase its product’s latest features from ... also be presenting a scientific poster on Disrupting Clinical Trials in The Cloud ...
Breaking Biology Technology: