Navigation Links
'Junk DNA' drives cancer growth
Date:5/2/2010

mally regulates the growth of other immune cells, but it is not usually found in B-cells. However in this case, the Hodgkin-/Reed Sternberg cells 'hijacked' this receptor for their own purposes by activating some of the 'junk DNA'. In fact the lymphoma cells activated hundreds, if not thousands, of LTRs all over the genome, not just one.

Hodgkin-/Reed Sternberg cells may not be the only cells that use this method to subvert normal controls of cell growth. The researchers found evidence of the same LTRs activating the same growth receptor in anaplastic large cell lymphoma, another blood cancer.

The consequences of such widespread LTR activation are currently still unclear, according to the study's authors. Such processes could potentially activate other genes involved in tumour development. It could also affect the stability of chromosomes of lymphoma cells, a factor that may explain why Hodgkin-/Reed Sternberg cells gain many chromosomal abnormalities over time and become more and more malignant.


'/>"/>

Contact: Paula Gould
p.a.gould@leeds.ac.uk
44-113-343-8059
University of Leeds
Source:Eurekalert

Page: 1 2

Related biology news :

1. Junk DNA could spotlight breast and bowel cancer
2. Saved by junk DNA
3. Research team finds important role for junk DNA
4. Junk DNA proves functional
5. Corals addiction to junk food
6. Evolving complexity out of junk DNA
7. Bits of junk RNA aid master tumor-suppressor gene
8. Scientists find community involvement, not only enforcement, drives success of marine reserves
9. The protein Srebp2 drives cholesterol formation in prion-infected neuronal cells
10. Sex in the Caribbean: Environmental change drives evolutionary change -- eventually
11. New research shows how gene function drives natural selection in important class of genetic elements
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... water window? It consists of radiations in the 3.3 ... the water in biological tissues. New theoretical findings show ... the water window. These could be the basis of ... the biological samples or to be used in high-precision ... mechanism needed to efficiently generate the harmonic radiationswhich are ...
(Date:8/21/2014)... Australian National University (ANU) team has successfully replicated one ... for biological systems powered by sunlight which could manufacture ... so is sunlight. It is an exciting prospect to ... and safely," said Dr Kastoori Hingorani, from the ARC ... Research School of Biology. , Hydrogen offers potential as ...
(Date:8/20/2014)... SALT LAKE CITY Researchers at Huntsman Cancer Institute (HCI) ... mutated forms of the gene that encodes BCR-ABL, the ... (CML). According to the American Cancer Society, nearly 6,000 ... , Drugs already in use, called tyrosine kinase inhibitors ... disease. They do not cure CML but control it ...
Breaking Biology News(10 mins):Water window imaging opportunity 2Water and sunlight the formula for sustainable fuel 2Blueprint for next generation of chronic myeloid leukemia treatment 2
... man is an island entire unto itself," but science ... colony of microscopic creatures. Every plant and animal species ... the early 20th century, scientists have argued what role ... of new species. A team of Vanderbilt biologists is ...
... A new University of Florida study shows cats ... in urban areas, prompting conservationists to urge pet owners ... challenge assumptions that urban areas are places of refuge ... important role in controlling insect pests and serving as ...
... of researchers co-led by a University of Minnesota scientist has ... threatens global wheat supplies and another that limits production of ... The sequencing of the genetic codes of wheat ... rust pathogen ( Melampsora larici-populina ) is expected to help ...
Cached Biology News:Could bacterial hitchhikers influence formation of new host species? 2UF study finds cats No. 1 predator to urban mockingbird nests 2UF study finds cats No. 1 predator to urban mockingbird nests 3Scientists sequence genomes of 2 major threats to American food and fuel 2
(Date:8/20/2014)... Livermore, California (PRWEB) August 20, 2014 ... to develop and apply the most complete climate ... challenging and demanding climate change issues. , Eight ... combining forces with the National Center for Atmospheric ... in the new effort. Other participating national laboratories ...
(Date:8/20/2014)... 2014 Not long ago, it was ... be performed late in the development cycle – even ... regulatory trends suggest that, like many things GxP, expectations ... recent years, multiple drug sponsors have been required by ... questions during phase I/II. It’s not only clinical trial ...
(Date:8/20/2014)... GraphDB™ 6.0 from ... the enterprise replication cluster, faster loading speeds, higher ... Elasticsearch. This release happens to coincide with a ... GraphDB™ was formerly known as OWLIM. ... enterprise resilient RDF triplestore will also benefit from ...
(Date:8/19/2014)... Pa. , Aug. 19, 2014 A ... has been nominated for a Centers for Disease Control ... addressing a major public health concern. ... System, is one of a team of researchers nominated ... Charles C. Shepard Science Award for Data Methods and ...
Breaking Biology Technology:New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3Are Extractable and Leachables going Phase-Appropriate? New Webinar Hosted by Xtalks 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3
... $80 million reduction in 2009 cash expenditures, SAN ... ) today announced a corporate restructuring that will,reduce its ... and reduce anticipated 2009 cash expenditures by more than ... the,Company,s business plan to be cash flow positive by ...
... - Conference Call Today at 4:30 p.m. Eastern Time ... MDVN ) today reported on its corporate progress ... "The third quarter represented another quarter of significant,achievement ... our partnering,agreement with Pfizer for Dimebon. This collaboration not ...
... Azur Pharma Limited ("Azur") today,announced that ... develop and,commercialise once-daily formulations of clozapine using ... delivery technologies, including,its NanoCrystal(r) technology., Clozapine ... Azur,s proprietary orally disintegrating tablet brand,FazaClo(r). Clozapine ...
Cached Biology Technology:Amylin Pharmaceuticals Announces Strategic Restructuring and Workforce Reduction 2Amylin Pharmaceuticals Announces Strategic Restructuring and Workforce Reduction 3Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 2Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 3Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 4Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 5Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 6Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 7Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update 8Azur Pharma and Elan Corporation (NYSE: ELN) Sign Agreement to Develop a Once-Daily Clozapine 2
... Effectively condenses and traps a wide variety ... vacuum pump oil. Easy-to-use glass condensation flask (GCF400) ... self contained jar for easy draining. Rapid cooling ... remove glass flask for quick solvent changes ...
... Analysis Note: Protein determined by Biuret ... 25 mM Tris-HCl, pH 7.6, 1 mM ... 2 Preparation Unit Definition: One unit ... per minute at pH 9.8 at 37 ...
Immulon 2 HB 1x8 Strip assembled, C-bottom; high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes....
Immulon 2HB, Flat Bottom, 50/Bx; high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes....
Biology Products: