Navigation Links
Juelich researchers take a look inside molecules
Date:8/20/2010

For their look into the nanoworld, the Jlich researchers used a scanning tunneling microscope. Its thin metal tip scans the specimen surface like the needle of a record player and registers the atomic irregularies and differences of approximately one nanometre (a billionth of a millimetre) with minuscule electric currents. However, even though the tip of the microscope only has the width of an atom, it has not been able so far to take a look inside molecules.

"In order to increase the sensitivity for organic molecules, we put a sensor and signal transducer on the tip," says Dr. Ruslan Temirov. Both functions are fulfilled by a small molecule made up of two deuterium atoms, also called heavy hydrogen. Since it hangs from the tip and can be moved, it follow the contours of the molecule and influences the current flowing from the tip of the microscope. One of the first molecules studied by Temirov and co-workers was the perylene tetracarboxylic dianhydride compound. It consists of 26 carbon atoms, eight hydrogen atoms and six oxygen atoms forming seven interconnected rings. Earlier images only showed a spot with a diameter of approximately one nanometre and without any contours. Much like an X-ray image, the Jlich scanning tunneling microscope shows the molecule's honeycombed inner structure, which is formed by the rings.

"It's the remarkable simplicity of the method that makes it so valuable for future research," says Prof. Stefan Tautz, Director at the Institute of Bio- and Nanosystems at Forschungszentrum Jlich. The Jlich method has been filed as a patent and can easily be used with commercial scanning tunnelling microscopes. "The spatial dimensions inside molecules can now be determined within a few minutes, and the preparation of the specimen is based predominantly on standard techniques," says Tautz. In the next step, the Jlich scientists are planning to calibrate the measured current intensity as well. If they are successful, the measured current intensities may allow the type of atoms to be directly determined.

After publishing initial images produced with the new method in 2008, the research group of Tautz and Temirov has now been able to explain the quantum mechanical principle of operation of the deuterium at the tip of the microscope. Their results were supported by computer-assisted calculations by the working group of Prof. Michael Rohlfing at the University of Osnabrck. The so-called short-range Pauli repulsion is a quantum-physical force between the deuterium and the molecule which modulates the conductivity and allows us to measure the fine structures very sensitively.

The Jlich method can be used to measure the structure and charge distribution of flat molecules which can be used as organic semiconductors or as part of fast and efficient future electronic devices. Large three-dimensional biomolecules such as proteins can be examined as soon as the techniques have been refined.


'/>"/>

Contact: Kosta Schinarakis
k.schinarakis@fz-juelich.de
Helmholtz Association of German Research Centres
Source:Eurekalert  

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Juelich researchers take a look inside molecules
(Date:2/8/2017)... NEW YORK , Feb. 7, 2017 Report ... ... and should reach $11.4 billion by 2021, growing at a ... Report Includes - An overview of the global markets for ... from 2015, estimates for 2016, and projections of compound annual ...
(Date:2/7/2017)... , February 7, 2017 ... Global Solutions Corporation [OTC: IDGS], ("Ipsidy" or the "Company") ... electronic transaction processing services, is pleased to announce the ... Company. Effective January 31, 2017, Philip ... of Directors, CEO and President.  An experienced payment industry ...
(Date:2/2/2017)... 2, 2017  EyeLock LLC, a market leader of ... paper " What You Should Know About Biometrics in ... user authenticity is a growing concern. In traditional schemes, ... However, traditional authentication schemes such as username/password suffer from ... authentication offers an elegant solution to the problem of ...
Breaking Biology News(10 mins):
(Date:2/25/2017)... ... February 25, 2017 , ... ... Clinical Trials in an ongoing effort to create meaningful change by increasing ... pharmaceutical research with emphasis on consumers and patients’ mental health well-being. , Both ...
(Date:2/24/2017)... ... February 24, 2017 , ... Delpor, Inc. (Delpor), a biotechnology company ... National Institute of Mental Health (NIMH) for the further advancement of the company’s 3-month ... technology and is expected to deliver therapeutic levels of olanzapine for a period of ...
(Date:2/24/2017)... Tenn. , Feb. 24, 2017 ... ("Provectus" or the "Company"), a clinical-stage oncology and ... regarding the deadline to participate in its previously ... units, consisting of shares of common stock and ... and holders of listed warrants. ...
(Date:2/24/2017)... Symic Bio, a biopharmaceutical company focused on ... therapeutics, announced today the completion of enrollment for the ... The trial will evaluate the safety and efficacy of ... of restenosis following angioplasty. "We,re pleased ... said Nathan Bachtell , M.D., Chief Medical Officer ...
Breaking Biology Technology: