Navigation Links
Journal of General Physiology explores mysteries of TRP channels in latest Perspectives series
Date:3/25/2009

Despite the large body of literature on transient receptor potential (TRP) channelsion channels that are directly involved in vision, taste, hearing, touch, olfaction, and other sensesvery little is known about their biophysics and protein structure, or the mechanisms that control their gating processes.

In its latest Perspectives in General Physiology series (http://jgp.rupress.org/current.shtml), the Journal of General Physiology (JGP) utilizes the contributions of leading experts to provide a critical overview of current research about TRP channel structure, and to point out areas in need of further exploration. The series gives special attention to the TRPA1 channel, which has been assigned many different functions.

In his introduction to the series, guest editor Ramon Lattore (Universidad de Valparaiso) provides an historical context for the TRP channel story, which dates back to the 1960s and now includes more than 85 known channels.

Series contributors include Rachelle Gaudet (Harvard University), Vera Moiseenkova-Bell and Theodore Wensel (Baylor College of Medicine), who write about the three-dimensional structure of TRP channels.

According to Latorre, knowing "how these channels are assembled from a structural point of view is critical to understand the molecular workings of these proteins and will allow for the development of intelligent strategies for the design of [targeted drugs]."

Other Perspectives contributors include Ombretta Caspani and Paul A. Heppenstall (EMBL Monterotondo and Universittsmedizin Berlin), Kelvin Y. Kwan and David P. Corey (Harvard University), and Sangsu Bang and Sun Wook Hwang (Korea University Graduate School of Medicine), who share their views about the questions concerning the modulation of the functional properties of the TRPA1 channel and, in particular, that regarding its temperature sensitivity.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. Tips from the American Journal of Pathology
2. New ecopsychology journal will premiere in spring 2009
3. Highlights from the March editions of ESA journals
4. Fifth annual Templeton-Cambridge fellowships awarded to 10 noted journalists
5. AGU journal highlights -- March 12, 2009
6. News from the March 2009 Journal of the American Dietetic Association
7. Springer and Senckenberg society to collaborate on life sciences and geosciences journals
8. Oxford Journals and the International Society for Computational Biology announce new partnership
9. Mycotoxin Research joins Springers life sciences journals program
10. British journal publishes inorganic chemistry research of NJIT professor
11. News from the February 2009 Journal of the American Dietetic Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... superior patient care by providing unparalleled technology to leaders of the medical imaging industry. ... recently added to the range of products distributed by Ampronix. Photo - ... ... ... ...
(Date:5/20/2016)... 2016  VoiceIt is excited to announce its ... By working together, VoiceIt and VoicePass will ... VoicePass take slightly different approaches to voice biometrics, ... and usability. ... partnership. "This marketing and technology partnership ...
(Date:5/16/2016)... , May 16, 2016   EyeLock LLC ... today announced the opening of an IoT Center of ... strengthen and expand the development of embedded iris biometric ... unprecedented level of convenience and security with unmatched biometric ... one,s identity aside from DNA. EyeLock,s platform uses video ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... New Haven, Connecticut (PRWEB) , ... May 25, ... ... today that the U.S. Food and Drug Administration (FDA) has granted the company’s ... This is the company’s second orphan drug designation granted by the FDA. ...
(Date:5/24/2016)... ... 24, 2016 , ... Cell therapies for a range of ... research at Worcester Polytechnic Institute (WPI) that yielded a newly patented method of ... The novel method, developed by WPI faculty members Raymond Page, PhD, professor of ...
(Date:5/24/2016)... 24, 2016   MedyMatch Technology Ltd ., the data ... real-time decision support tools in the emergency room, announced today ... Israeli Advanced Technology Industries (IATI) BioMed Conference. ... 15th National Life Sciences and Technology Week, and is ... Hotel in Tel Aviv, Israel . ...
(Date:5/24/2016)... ... , ... Last week, Callan Capital, an integrated wealth management firm specializing in ... San Diego Life Science event at the Estancia La Jolla Resort and Spa. , ... speakers Dr. Rich Heyman, former CEO of Aragon and Seragon, and Faheem Hasnain, former ...
Breaking Biology Technology: