Navigation Links
Joslin research finds nearly three-quarters of youths with diabetes insufficient in vitamin D
Date:12/15/2008

BOSTON [Dec. 15, 2008] Three-quarters of youths with type 1 diabetes were found to have insufficient levels of vitamin D, according to a study by researchers at the Joslin Diabetes Center findings that suggest children with the disease may need vitamin D supplementation to prevent bone fragility later in life.

"To our surprise, we found extremely high rates of vitamin D inadequacy," said Lori Laffel, M.D., M.P.H., Chief of the Pediatric, Adolescent and Young Adult Section at Joslin, Investigator in the Section on Genetics and Epidemiology, and senior author of the paper. "We didn't expect to find that only 24 percent of the study population would have adequate levels."

The study, which appears in the January 2009 issue of The Journal of Pediatrics, measured levels of serum 25-hydroxyvitamin D in 128 youths with type 1 diabetes ranging in age from 1.5 to 17.5 years. The study sample included subjects with recent onset of diabetes as well as those who had long-established diabetes.

It found 24 percent had sufficient levels, 61 percent with insufficient levels and 15 percent to be deficient or having the lowest levels. Generally, those with deficient levels were the oldest of the subjects. In fact, 85 percent of the adolescents in the sample demonstrated inadequate vitamin D levels.

The paper notes that diabetes itself can negatively impact bone health and is associated with a modest reduction in bone mineral density and strength and an increase in fracture risk among those middle-aged and older. At the same time, vitamin D deficiency in infants and children is associated with bone deformation, while less severe vitamin D insufficiency prevents youths from attaining their optimal bone mass and may contribute to increased fracture risk later in life, the paper adds.

For these reasons, vitamin D deficiency or insufficiency poses an increased risk for children with diabetes, the paper says. In addition to reduc
'/>"/>

Contact: Kira Jastive
kira.jastive@joslin.harvard.edu
617-732-2418
Joslin Diabetes Center
Source:Eurekalert

2

GOOD

Page: 1 2

Related biology news :

1. Joslin researchers uncover potential role of leptin in diabetes
2. Researchers create new class of fluorescent dyes to detect reactive oxygen species in vivo
3. GUMC researchers find gene function lost in melanoma and glioblastoma
4. Preventing a broken heart: Research aims to reduce scarring from heart attacks
5. Mayo Clinic research on tamoxifen leads to recommendation for CYP2D6 gene test
6. Ireland Cancer Center researcher finds most triple-negative breast cancers express muc-1 target
7. Pitt, NETL researchers report molecular chain reaction thought to be impossible
8. MIT researchers explain mystery of gravity fingers
9. Easton honored with inaugural AACR Outstanding Investigator Award in Breast Cancer Research
10. UC San Diego researchers use metagene portraits to reveal distinct stages of kidney formation
11. UQ research targets West Nile virus and dengue fever
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2009)...n has released an updated position paper on vegeta...ned, are healthful and nutritious for adults, infa... and treat chronic diseases including heart diseas...n, published in the July issue of the Journal of ... Association,s official stance on vegetarian diets...
(Date:7/1/2009)... time, scientists have shown that chromosomal abno...yos, even those produced by young, fertile couples... for Human Genetics and the University Fertility C...nnual conference of the European Society of Human ...1), that the surprising finding meant that current...
(Date:6/30/2009)...tulated that food consumption in birds and mammals...would eat as much as they could while food was ple... allow them to. However, recent research has show...reaches a limit, even in animals with high nutrien...t the Research Institute of Wildlife Ecology in Vi...
(Date:6/30/2009)...biotechnology to help address significant social a...th" by the rigid opposition of some groups and reg...g of genetically modified trees, scientists argue ... a regulatory environment that considers genetical...sis, and is focused on the end product rather than...
Breaking Biology News(10 mins):ADA releases updated position paper on vegetarian diets 2Chromosomal problems affect nearly all human embryos 2Chromosomal problems affect nearly all human embryos 3Key to evolutionary fitness: Cut the calories 2Anti-biotech groups obstruct forest biotechnology 2Anti-biotech groups obstruct forest biotechnology 3Story tips From the Department of Energys Oak Ridge National Laboratory May 2009 8333 1Story tips From the Department of Energys Oak Ridge National Laboratory May 2009 8333 2Stroudsburg PA Woman Earns Governors Achievement Award as Direct Care Worker of the Year 44902 1Biosite Incorporated Issues Voluntary Nationwide Recall for Cardiac Marker Test 44898 1Biosite Incorporated Issues Voluntary Nationwide Recall for Cardiac Marker Test 44898 2Casenet Names Bill Wisotzkey Vice President of Product Management and Design 44894 1Casenet Names Bill Wisotzkey Vice President of Product Management and Design 44894 2
... matter how healthy a life one leads, no person ha... though the advances of the modern age may have ex...ere are genetic limits to longevity. One prominent...n of damage done to DNA and proteins by “free radi...tabolic activity of mitochondria. , This damage is...
... matter how healthy a life one leads, no person ha... though the advances of the modern age may have ex...ere are genetic limits to longevity. One prominent...n of damage done to DNA and proteins by “free radi...tabolic activity of mitochondria. , This damage is...
...ctors today presented more evidence that it,s time...n and amoxicillin to step aside when it comes to t...dications used to treat the strep germ, the bug th...n every year, simply aren,t doing the job and aren...alosporins. In results presented today at a large ...
...e first close-up look at a pro-inflammatory signal...s suggests that researchers "should rethink what t...fly model, scientists say. , Reporting in the Oct.... at the University of Illinois at Urbana-Champaign...in-1 receptor-associated kinase-4 (IRAK-4). , The...
Other Biology News:Carnegie Mellon scientists create PNA molecule with potential to build nanodevices 2Navigating the brain for sense of direction as paradigm for higher cognitive functions 2Penicillin, amoxicillin: Step aside for strep throat treatment 2Penicillin, amoxicillin: Step aside for strep throat treatment 3Molecular research suggest shift needed in how some drugs are created 2
(Date:7/3/2009)...re/ -- Tomorrow, Corey Reich, an ALS patient from ...ncisco Giants and Los Angeles Angels of Anaheim ba...the ALS Therapy Development Institute (ALS TDI). ...reness of amyotrophic lateral scleroses (ALS, Lou ...hich he suffers and for which there is no known ca...
(Date:7/2/2009)... Advanced Chemical Transport, one of the leading ...ed a multi-year partnership with Gilead Sciences I.... , , ACT will provide Environmental services -...uck services, spill response, site specific servic...rporate headquarters in Sunnyvale, CA. , , ACT...
(Date:7/2/2009)...rstCall/ -- Lixte Biotechnology Holdings (OTC Bull...rs of the National Institute of Neurological Disor...stitute (NCI), National Institutes of Health and L...ances the effectiveness of two standard chemothera...search is being conducted under a Cooperative Rese...
(Date:7/1/2009)...identifies and removes systematic bias, noise and ...ould lead to more precise and reliable measurement...e future industrial applications. , Known as seq...he technique could also reduce the amount of exper...p distinguish true nanoscale phenomena from experi...
Breaking Biology Technology:Bay Area Youth to Represent ALS Patients at Giants' and Angels' Baseball Games on July 4th 2Bay Area Youth to Represent ALS Patients at Giants' and Angels' Baseball Games on July 4th 3Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances the Effectiveness of Standard Cancer Chemotherapy in Animal Models 2Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances the Effectiveness of Standard Cancer Chemotherapy in Animal Models 3New statistical technique improves precision of nanotechnology data 2New statistical technique improves precision of nanotechnology data 3New statistical technique improves precision of nanotechnology data 4
...ared in Genetic Engineering News (Volume 26, No.... an invention secretly in one,s own shop, even for...ause a court to invalidate a patent filed later to...d in response to a defense where an accused infrin...id due to prior public use. The question turns on ...
...ne is a concept that appears a long way from becom...led genetic-based medicine is closer than we think...rofiles will be used to identify the patient,s pre...sease management programs tailored to individual g...ephens Cracking the human genome has made persona...
...ne company that helps consumers shop for more affo...create a new healthcare paradigm. , ,The Oshkosh-b... where consumers can self-register and gain free a...n about prescription medications. And with America..., the site,s developers believe consumers - and th...
...is at a crucial moment in the development of stem ...pporters of human embryonic stem cell research to ...rena this fall. , ,Doyle, speaking at a symposium ...ve think thank, said the reason the nation is at a...who want to see stem cell research stopped in it t...
Other Biology Technology:With patents and research tools, when is private really public? 2With patents and research tools, when is private really public? 3With patents and research tools, when is private really public? 4With patents and research tools, when is private really public? 5Medical College researcher working to make genetic-based medicine a reality 2Medical College researcher working to make genetic-based medicine a reality 3Will BidRx start a drug price war? 2Will BidRx start a drug price war? 3Will BidRx start a drug price war? 4Doyle says practical politics must advance embryonic stem cell research 2Doyle says practical politics must advance embryonic stem cell research 3
...e high-performance triple quadrupole 1200L sets th... environment - incorporating the latest technologi... chromatography analytical needs. The Atmospheric...mission Quadrupole Analyzer provide superior selec...
... you need to make your strain of cells competent o...dvantage of Lucigen’s unrivalled expertise i...formance Custom Competent Cell Service offers: C...h transformation efficiencies Fast turnaround ...
Glucagon-like peptide-1 (GLP-1 (1-36) amide)
...mall Molecule Localization in Early Drug Developme...l drug compound localization data in early drug de...rys imaging mass spectrometry service maps unlabe... so you can localize drugs and metabolites prior t...
Biology Products: