Navigation Links
Johns Hopkins scientists identify a key to body's use of free calcium
Date:1/23/2014

d attached them to calcium channels, calmodulin and CaBP4. When two molecules locked together, the color changed. By measuring color changes, the researchers could then tell which molecules bound to each other.

"Our experiments established that calmodulin and calcium-binding proteins work by binding to distinct parts of the calcium channel," Yue says. "More generally, we have been able to investigate how large molecules such as these function in living cells."

The "live light show" permitted by the use of light markers should help scientists develop new drugs that target calcium channels, Yue adds. Some such drugs already exist, including calcium channel blockers that lower blood pressure by targeting a particular kind of calcium channel found in blood vessels.

Blocking calcium channels might help with other diseases, too, Yue says. For example, researchers have found that an overload of calcium in certain parts of the brain may drive some neurodegenerative diseases, such as Parkinson's. Blocking the calcium channels found in those trouble spots the kind of calcium channels in Yue's study could be a way to fight the debilitating brain disease.


'/>"/>

Contact: Catherine Kolf
ckolf@jhmi.org
443-287-2251
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Johns Hopkins researchers uncover genes at fault for cystic fibrosis-related intestinal obstruction
2. Johns Hopkins researchers link 2 biological risk factors for schizophrenia
3. The Johns Hopkins Center for Inherited Disease Research receives $101 million
4. 3 Johns Hopkins researchers named AAAS Fellows
5. NREL and Johnson Matthey announce 5-year collaboration on biofuels
6. 3 Johns Hopkins researchers recognized for medical inventions
7. Johns Hopkins And Belgian research center to expand health care applications for silicon nanotech
8. 4 Johns Hopkins researchers named AAAS Fellows
9. Genetic predictors of postpartum depression uncovered by Hopkins researchers
10. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
11. Queens scientists seek vaccine for Pseudomonas infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... SHELTON, Conn. , Oct. 15, 2014 NXT-ID, Inc. ... a biometric authentication company focused on the growing mobile commerce market ... NASDAQ MarketSite in Times Square on Monday October 13 th . ... with CTO David Tunnel and angel investor Mr. ... Gino Pereira , CEO of NXT-ID thanked his investors and employees ...
(Date:10/14/2014)... millions of years since T. rex took ... University scientists is breathing life back into dinosaurs using ... The research has important implications for how dinosaurs used ... the sense of smell and cool their brains. ... doctoral student Jason Bourke, lead author of the new ...
(Date:10/14/2014)... CA – October 14, 2014 – Scientists from The ... from the National Institutes of Health (NIH) to lead ... virus-induced hemorrhagic fever disease in Africa. The study aims ... why some patients die, while others survive the inflection. ... understand the basic mechanism of how Lassa fever virus ...
Breaking Biology News(10 mins):Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3Scripps Research Institute team receives $6.6 million to investigate deadly Lassa virus 2
... the first-ever study to assess the social impact of ... that approximately 35 percent of children with food allergies, ... to have experienced bullying, teasing, or harassment as a ... experiencing teasing or harassment, 86 percent were reported to ...
... chevron formation or cyclists learned the value of drafting, fungi ... so as to spread them as high and as far ... , spews thousands of spores nearly simultaneously to form a ... a wind that carries many of the spores 20 times ...
... that plasmonic nanobubbles, generated around gold nanoparticles with a ... vivo by creating tiny, shiny vapor bubbles that reveal ... in the October print edition of the journal ... on zebra fish implanted with live human prostate cancer ...
Cached Biology News:First study of its kind finds children with food allergies are often victims of bullying 2Fungal spores travel farther by surfing their own wind 2Fungal spores travel farther by surfing their own wind 3Fungal spores travel farther by surfing their own wind 4'Gold' fish thrive, cancers die 2'Gold' fish thrive, cancers die 3
(Date:10/18/2014)... The report "1,6-Hexanediol Market by Application ... 2019", analyzes the global market on the basis ... industry details such as the key drivers, current ... , Browse 81 Market Data Tables and 29 ... on “1,6-Hexanediol Market by Application and by Geography ...
(Date:10/18/2014)... The Asian Electronic Medical Record (EMR) market report defines and ... of revenue. The electronic medical record market in the Asian ... at a CAGR of 9.4% from 2013 to 2018. , ... (EMR) market, to get an idea of the in-depth analysis ... the market in the same region, and is supported by ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... Stress, Holter Monitor), by End-user (Hospitals, Home/Ambulatory, Research ... (Single, 3-6, 12) -Global Forecast to 2020” provides ... challenges, opportunities, current market trends, and strategies impacting ... estimates and forecasts of the revenue and share ...
(Date:10/17/2014)... 17, 2014 For the seventh ... as published in today’s print issue of Science ... Top Employers Survey polled employees in the biotechnology, ... best employers. Rankings were determined based on ... rate their companies on 23 characteristics, including financial ...
Breaking Biology Technology:1,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 2The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 3The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 4The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 5The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 2The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 3The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 4The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 5DuPont Named Top Employer by Science Magazine 2DuPont Named Top Employer by Science Magazine 3
... (2004) Synaptotagmin V and IX isoforms control , ... Sci 117:3119-3127. , ... , Journal of Cell Science, Iezzi and ... and the p Silencer 1.0-U6 vector in , ...
... Byrom, Vince , Pallotta, David Brown*, and Lance Ford* ... Austin, TX 78744-1832 * Corresponding authors <A , ... , , ... Labeling GAPDH and c-myc siRNA with either fluorescein , ...
... GLOBINclear-Human Globin mRNA Removal Kit , , ... from blood total RNA with a simple magnetic bead procedure (no , ... Increases sensitivity of gene , ... , Integrates ...
Cached Biology Technology:Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function 2Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function 3Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function 4Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 2Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 3Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 4Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 5Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 6Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 7Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 8Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 9Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 10Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 11Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 12Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 13Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 14Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 15Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 16Unmask Blood RNA for Gene Expression Profiling 2Unmask Blood RNA for Gene Expression Profiling 3Unmask Blood RNA for Gene Expression Profiling 4
Certified U.S. origin. Bovine Serum:, *Certified U.S. origin. Available raw, nonsterile filtered, or sterile filtered. , , *Sterility tested , , *Low Hemoglobin levels , , *Mycoplasma testing upon...
...
12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry....
Full-length cDNA 5-PRIME end of clone CS0DE013YM09 of Placenta of Homo sapiens (human). [Source:Uniprot/SPTREMBL;Acc:Q86TS7] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: