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John Theurer Cancer Center researchers shared 14 leading edge studies at recent ASCO meeting
Date:7/18/2011

dian age 58, with advanced stage mantle cell lymphoma treated with one of the two therapies. The model was not validated for these patients. The authors conclude that the study highlights the need to develop and validate models that can identify patients treated with dose-intensive approaches who are at risk for poor survival.

Association between chronic myeloid leukemia (CML) treatment responses and patient satisfaction, functioning, and quality of life (QOL): Patient survey results.

Stuart L. Goldberg, M.D. and colleagues assessed patients' awareness of chronic myeloid leukemia (CML) treatment response categorizations and the association between treatment responses and satisfaction, functioning, and quality of life. Patients were invited to participate in an online survey through the Association for Cancer Online Resources; 123 responded. Nearly all reported they were in complete hematological response. In this well-educated population (96% had some college), 90% of patients were aware of the different treatment response categories. However, 71.5% felt CML patients need more information on types of responses, with the desire for information to come from their physicians (67%) versus other staff (28%) or pamphlets (24%). Patients achieving major molecular response to treatment (MMR) had higher overall self- reported health status versus patients in complete cytogenetic response (CCyR). Complete cytogenetic response is the absence of the defective chromosome that causes the disease, while major molecular response is defined as a level of .1 percent or lower of the BCR-ABL oncoprotein as measured by a more sensitive test than traditional cytogenetic analysis. The authors conclude that from the patients' perspective, achievement of MMR is an important milestone associated with improved satisfaction with their physician, medication, daily functioning, and outlook on life. Additional research is needed to assess the best ways to help patients understand diff
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Contact: Amy Leahing
Amy.leahing@zibbel.com
John Theurer Cancer Center
Source:Eurekalert

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