Navigation Links
Jefferson scientists discover a key protein regulator of inflammation and cell death
Date:1/22/2009

ation of AIM2 also leads to death of the infected cells, which removes the damaged cells from the body. This prevents the pathogen from replicating in the cells and spreading to other parts of the body. The fact that AIM2 can induce cell death raises the possibility that AIM2 might function as a tumor suppressor, by killing cells with damaged DNA before they transform into cancers. Inactivation of AIM2 thus might confer a growth advantage to abnormal cells and lead to the development of cancer.

"The discovery and understanding of the AIM2 inflammasome should enable scientists to design novel therapeutics that modulate its activity," Dr. Alnemri said. "Such therapeutics may be useful for the treatment of nucleic aciddependent pathogenic and autoimmune diseases, such as arthritis and systemic lupus erythematosus," Dr. Alnemri said.


'/>"/>

Contact: Emily Shafer
emily.shafer@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Jefferson urologists studying regenerated neo-bladder to help spinal cord injury patients
2. Jefferson scientists studying the effects of high-dose vitamin C on non-Hodgkin lymphoma patients
3. Jefferson receives $11.6M NIH grant to study novel mechanisms of heart failure
4. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
5. Jefferson Department of Surgery announces new pancreas tumor registry
6. UK scientists working to help cut ID theft
7. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
8. Comet probes reveal evidence of origin of life, scientists claim
9. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
10. Male elephants get photo IDs from scientists
11. Scientists retrace evolution with first atomic structure of an ancient protein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced the ... Security Systems Market" report to their offering. ... perimeter security market is estimated to grow at a CAGR ... holds a larger share in this market, Canada ...
(Date:12/17/2014)... 15, 2014  HITLAB SM announced today its completion ... its adherence to current U.S. Food and Drug Administration ... smart device and smart phone application trials utilizing the ... "HITLAB is determined to improve global healthcare access, ...
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... advances in technology, it is important to upgrade biometric ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... HOBOKEN, N.J. The Center for Science Writings at Stevens ... Versus Selfishness Among ,Wolf Birds," a talk by Bernd Heinrich, ... in the Babbio Center, Room 122, from 4 p.m. to ... Heinrich "not just a great naturalist writer; he,s a great ...
... Walter is one good gumshoe. The University of Alberta medical ... to glaucoma. , Glaucoma is a leading cause of blindness ... brain from understanding what patients see. Scientists have long suspected ... to figure out what the gene does and why some ...
... CA (March 20, 2009) A rigorous environmental cleaning ... Staphylococcus aureus (MRSA) and other multidrug-resistant organisms ... a new study released today at the annual ... America (SHEA). Researchers found that following an ...
Cached Biology News:Genetic sleuth solves glaucoma mystery 2Environmental cleaning intervention reduces transmission of multidrug-resistant organisms in ICUs 2
(Date:1/22/2015)... 22, 2015  Transwestern | RBJ today announces the firm brokered ... for Shire a leading biopharmaceutical company, at Two Ledgemont Center ... Robert Richards , president, and Brian Cohen , ... entire five-floor building at 95 Hayden Ave. Photo ...
(Date:1/22/2015)... 22, 2015 The laboratory information management ... witnessed a number of technological advancements due to factors ... growing need to integrate healthcare systems, and increasing government ... in system integration. Key players in the market focus ...
(Date:1/22/2015)... January 22, 2015 zFlo Motion , ... to announce an exciting product from a new partner. ... solutions over the past 15 years, with offerings in the ... their 3D IMU system (inertial measurement unit), iSen, is opening ...
(Date:1/22/2015)... NJ (PRWEB) January 22, 2015 ... technologies such as the Bioruptor® and complete solutions ... system for chromatin immunoprecipitation, alleviating the need for ... and controls needed for ChIP of histones or ...
Breaking Biology Technology:Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
... April 11, 2012  Ikaria, Inc., a critical care ... for critically ill patients, today announced that Joseph ... In this role, Dr. Stauffer will be responsible ... regulatory activities related to Ikaria,s commercialized product, INOMAX® ...
... Advanced Biofuels, LLC, the biobutanol technology leader, commented ... patent infringement. (Logo: http://photos.prnewswire.com/prnh/20120209/MM50763LOGO ... for commercial production of isobutanol.  This is especially ... our ,188, ,889 and related patents filed by ...
... Systems Corporation has recently signed a strategic alliance ... Psyche,s award winning Anatomic Pathology solution, will be ... Lab, Siemens laboratory information system. ... is built on a contemporary architecture that is ...
Cached Biology Technology:Ikaria® Appoints Chief Medical Officer 2Ikaria® Appoints Chief Medical Officer 3Butamax™ Responds to Gevo Patent Infringement Lawsuit 2Psyche Systems Corporation Signs Strategic Alliance with Siemens Healthcare to Provide Anatomic Pathology Solutions 2
... The DNA quantitation kit is used to quantitate ... presence of RNA or protein. With this kit, ... can be detected with a VersaFluor or other ... of 10 ng per ml to 5 micrograms ...
... DeCypher combines enterprise-scale sequence analysis software with ... bioinformatics analyses. With DeCypher, you can perform searches ... ESTs vs NCBI NT database in under 6 ... to genomic DNA Use HMM analysis ...
...
Mouse polyclonal antibody to ALS2CR8 - amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8...
Biology Products: