Navigation Links
Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
Date:9/23/2008

xin which shuts down protein production in the cancer cells."

"It worked well in our cell culture models and now we are moving into pre-clinical experiments," Brody says.

The agent will not attack normal cells because the molecular machinery needed to turn on mesothelin is not found in normal cells, Brody says. Additionally, Sawicki has modified the diphtheria DNA to ensure that toxin that might be released from dying cancer cells is not taken up by healthy, normal cells.

But the researchers are now perfecting even more stringent measures to ensure safety, he says. "We can't help being hopeful," he says. "Our findings suggest that such a strategy will work in the clinical setting against the majority of pancreatic tumors."


'/>"/>

Contact: Ed Federico
ed.federico@jefferson.edu
Thomas Jefferson University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Jefferson receives $11.6M NIH grant to study novel mechanisms of heart failure
2. Jefferson scientists studying the effects of high-dose vitamin C on non-Hodgkin lymphoma patients
3. Jefferson urologists studying regenerated neo-bladder to help spinal cord injury patients
4. ESA trains next generation of atmospheric scientists
5. Scientists find redesigned hammer that forged evolution of pregnancy in mammals
6. Scientists discover a new Pacific iguana
7. Scientists identify the genes that cause blindness produced by corneal edema
8. UNC scientists turn human skin cells into insulin-producing cells
9. Scientists isolate cancer stem cells
10. Scientists form alliance to develop nanotoxicology protocols
11. Scientists point to forests for carbon storage solutions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Orleans, LA -- Nancy Buccola, MSN, APRN, PMHCNS-BC, ... Health Sciences Center New Orleans School of Nursing, ... locations of genetic material associated with schizophrenia and ... system and schizophrenia. The study, Biological insights from ... 22, 2014 in Nature , available at ...
(Date:7/22/2014)... In Jeju, a place emerging as a world-famous vacation spot ... eruption occurred on the island. The Korea Institute of Geoscience ... that indicated that a recent volcanic eruption was evident 5,000 ... out the date when lava spewed out of a volcano ... as well as the one the whole peninsula. , The ...
(Date:7/22/2014)... which sees them prevent their daughters from breeding, and ... , Research into the desert creatures which live in ... shows that the alpha female can flourish when it ... how this way of life, also found in many animals ... sinister side. , Dominant meerkats control breeding within their ...
Breaking Biology News(10 mins):LSUHSC contributes to work identifying new DNA regions associated with schizophrenia 2Jeju Island is a live volcano 2
... ingredient in vinegar, acetic acid, can effectively kill ... an international team of researchers from Venezuela, France, ... the online open-access journal of the American Society ... as an inexpensive and non-toxic disinfectant against drug-resistant ...
... have found that a single genetic mutation causes resistance to ... With the continuing rise of resistance the research, published in ... say that this knowledge could help improve malaria control strategies. ... wide range of methods to narrow down how the resistance ...
... Scarborough shows that animal dispersal is influenced by a gene ... The study, which was carried out by UTSC Professor Mark ... first aimed at gaining a functional understanding of how genes ... common fruit flies ( Drosophila melanogaster ), the researchers observed ...
Cached Biology News:Vinegar kills tuberculosis and other mycobacteria 2Vinegar kills tuberculosis and other mycobacteria 3Researchers at LSTM crack the genetic secret of mosquito resistance to DDT and ITNs 2New study shows a genetic link between feeding behavior and animal dispersal 2
(Date:7/21/2014)... College of Arts and Sciences has received a ... nanoparticles. , Mathew M. Maye, associate professor of ... from the National Science Foundation (NSF). The award ... nanostructures, the results of which may impact gas ... , Maye,s approach is novel, in that ...
(Date:7/21/2014)... , July 21, 2014 ... & USA Cancer Biomaker ... Forecasts ResearchMoz presents this most up-to-date ...   to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, ... Pipeline Analysis. GLOBAL & ...
(Date:7/20/2014)... 2014 NSG Precision Cells has ... and spectrophotometer calibration standards for over ... released many products that have transformed the spectroscopy ... their solid-state calibration standards. , NSG’s solid-state calibration ... release in 2008. NSG started manufacturing UV ...
(Date:7/18/2014)... , July 18, 2014  Neogen Corporation (Nasdaq: ... Snyder , Neogen,s chief operating officer and president, has ... will work as a consultant going forward on special ... Snyder has been in this position since September 2013. ... by James Herbert , who has been Neogen,s ...
Breaking Biology Technology:Syracuse University chemist to use NSF grant to study materials chemistry, nanoscience 2Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 2Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 3Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 4Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 5Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 6How NSG Precision Cells Spectrophotometer Calibration Standards Makes NIR Work Easier 2How NSG Precision Cells Spectrophotometer Calibration Standards Makes NIR Work Easier 3
... Oncolytics Biotech Inc. (TSX:ONC, NASDAQ: ONCY ) ("Oncolytics" or the "Company") ... ended March 31, 2010 . , ... "We have recently seen a range of ... mechanism of action and provided evidence of synergies with currently approved ...
... PARIS , May 12, 2010 , ... - New Outcomes Trial to Expand Evidence ... , ... of a multinational, randomized double-blind Phase IIIb trial,PALLAS, to assess the potential clinical benefit ...
... Scientists from Zymes LLC, the University of Windsor ... of Canada presented their research at the 2010 ... 28th .  The paper entitled, " Protection of SNpc neurons by ... disease: The role of neurotrophic factors," describes a potential treatment ...
Cached Biology Technology:Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 2Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 3Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 4Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 5Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 6Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 7Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 8Oncolytics Biotech(R) Inc. Announces First Quarter 2010 Results 9Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 2Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 3Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 4Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 5Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 6Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 7Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 8Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 9Sanofi-aventis Initiates 10,000 Patient Study With Multaq(R) in Permanent AF 10Zymes’ Water Soluble CoQ10 Decreases Symptoms in Animal Models of Parkinson’s Disease 2
... Stand-96 is designed for paramagnetic bead precipitation ... ml PCR plates with no additional accessories. ... in a standard SBS 96-well microplate footprint. ... magnets guarantees easy and fast (as little ...
... UVP's HybriCycler Hybridization Oven with circular ... bottles and tubes. HC-3000 HybriCycler Oven features ... Non-skid leveling feet balance the unit., ... durable acrylic, carousel is ,easily removable ...
... HB-500 Minidizer is a personal desktop unit ... and space requirements. , Rotation speed set ... ambient to 80o C , Bottle capacity ... ml or 15 ml conical ,plastic bottles ...
... based purification systems provide high speed purification ... They offer increased throughput and reproducible results. ... KingFisher mL and KingFisher 96, covering sample ... system consists of an instrument, specially designed ...
Biology Products: