Navigation Links
Jay Keasling wins Heinz Award
Date:9/12/2012

cells, and the re-designing and engineering of existing biological systems, such as microorganisms.

Keasling scored his first major breakthrough in the synthetic biology field in 2003 when he and his colleagues reported that by transplanting genes from yeast and the sweet wormwood tree (Artemsisia annua) into E. coli bacteria, then by-passing the E. coli's metabolic pathway and engineering a new one based on the mevalonate pathway in yeast, they were able to induce the bacteria to produce a chemical precursor to artemisinin, the world's most powerful drug for treating malaria.

In 2004, Keasling received a $42.6 million grant from the Bill and Melinda Gates Foundation, through the Institute for OneWorld Health, a San Francisco-based nonprofit pharmaceutical company, to further develop his microbial artemisinin technology. This led to a partnership with Amyris, a biotech start-up co-founded by Keasling, that engineered a strain of yeast (Saccharomyces cerevisiae) capable of producing high levels of artemisinic acid, the immediate precursor to artemisinin. Today, the pharmaceutical company Sanofi-Aventis is poised to provide mass-produced low-cost microbial-based artemisinin that will stabilize supplies and prices and make the drug far more accessible for those who need it most.

Artemisinin is the key component in artemisinin-based combination therapies (ACTs), which are the World Health Organization's recommended first-line treatment for malaria. Currently, artemisinin is extracted from sweet wormwood, a fern-like plant grown mostly in China and Vietnam, and manufactured through costly chemical synthesis. Weather and other conditions have led to fluctuating prices and drug shortages. According to the World Health Organization, each year nearly 500 million people become infected with malaria, and nearly three million, mostly children, die from it.

For his breakthrough with artemisinin, Keasling in 2009 received the first Biotech
'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Keck award enables Carnegie Mellon and Stanford to dramatically expand crowdsourced RNA design
2. MARC travel awards announced for EB 2012
3. Space research institute honors Sen. Hutchison with Pioneer Award
4. Autism Speaks awards $1.1 million to fund high priority studies
5. Young Scientist Award for Socio- and Econophysics 2012 for Arne Traulsen
6. MARC travel award announced for the 2012 ASCI/AAP Joint Meeting
7. Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
8. Genzyme/ACMG Foundation Genetics Training Award in Clinical Biochemical Genetics announced
9. 2012 ACMG Foundation/Signature Genomic Laboratories Travel Award winner announced
10. NYU School of Medicine presents 2012 Dart/NYU Biotechnology Achievement Awards
11. Copernicus Award 2012 for German-Polish collaboration in business information systems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Jay Keasling wins Heinz Award
(Date:10/15/2014)... University Mainz (JGU) as a full member, ensuring ... a significant nationwide standing in the field of ... Gutenberg University Mainz as a full member of ... and international competition for the best minds and ... proud that Mainz University has been recognized as ...
(Date:10/15/2014)... Fred Alt will be awarded the 44th Rosenstiel Award ... for his pioneering research exploring the mechanisms of genomic ... cancer cells. Alt is the second alumnus to win ... Nobel Prize in 2003. , Alt is the Charles ... at Harvard Medical School and an investigator at the ...
(Date:10/14/2014)... 2014)—It,s been millions of years since T. rex ... by Ohio University scientists is breathing life back into ... dinosaur snouts. The research has important implications for how ... to enhance the sense of smell and cool their ... Ohio University doctoral student Jason Bourke, lead author of ...
Breaking Biology News(10 mins):Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3
... Lysmata amboinensis usually live in monogamous pairs, but dark ... Central,s open access journal Frontiers in Zoology shows ... attack and kill each other until only a single pair ... This means that they start out as males but, as ...
... pollination, the number of seeds they produce, or their relative ... of pollen. The number of visits a plant may receive ... plant density. But what if a plant happens to grow ... pollinators visiting its flowers? Will all the effort put into ...
... and depth of the Deepwater Horizon oil spill ... severity of ecological damage and to develop restoration plans for ... report by the National Research Council. A broad approach ... production -- in addition to replacing natural resources damaged by ...
Cached Biology News:Violent passions jealous cleaner shrimp murder their rivals 2How does a plant survive with few mates or pollinators? A European herb has figured out its own way 2How does a plant survive with few mates or pollinators? A European herb has figured out its own way 3New report offers broad approach to assessing impacts of ecological damage 2New report offers broad approach to assessing impacts of ecological damage 3
(Date:10/22/2014)... 22, 2014 Nuvilex, Inc. (OTCQB: NVLX) – ... people worldwide are living with diabetes, with  that number ... The global market for diabetes treatments is approximately $500 ... worldwide died from pancreatic cancer.  Pancreatic cancer is the ... in the United States , and ...
(Date:10/20/2014)... YORK , Oct. 20, 2014 ... their experimental ZMapp™ antibody therapeutic to fight the ... how difficult and time-consuming the production of pharmaceuticals ... market research publisher said that while some may ... of this compound, those with industry knowledge are ...
(Date:10/20/2014)... 20, 2014 , A major ... and the delivery of care has revealed changing trends ... inequalities in the provision of healthcare services across the ... by United European Gastroenterology (UEG), have been announced today ... awareness of the burden of GI disorders across ...
(Date:10/20/2014)... 2014 Earle Martin , ... today that Ellen Teplitzky, an experienced attorney specializing ... pharmaceutical industry, has joined the firm as Director ... services practice. NDA Partners provides legal services, ... testimony, to top law firms and their clients ...
Breaking Biology Technology:Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
... March 14 GHI Medical, a national,leader in ... to,correlate the results of a current test used ... is called the TrichoBioScan(TM)., The TrichoBioScan(TM) consists ... with an in-depth microscopic analysis of a person,s,hair ...
... 14 ,Renovis, Inc. (Nasdaq: RNVS ), a biopharmaceutical ... major medical needs in the areas of,neurological and inflammatory ... year ended December 31, 2007., Revenue for the ... was,$1.3 million and $9.8 million, respectively, compared to $2.2 ...
... Diagnostics,Incorporated (NYSE: DGX ), the nation,s leading ... it is scheduled to speak,at the Lehman Brothers ... 2008, at The Loews Miami Beach Hotel, Miami, ... at 9:00 a.m.,Eastern Time., The presentation will ...
Cached Biology Technology:Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 2Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 3Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 4Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 5Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 6Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 7Quest Diagnostics to Speak at Lehman Brothers 11th Annual Global Healthcare Conference 2
BD BioCoat Collagen IV 35 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse collagen type IV....
... are designed for sequencing inserts cloned into ... or T3 RNA polymerase promoters, or lambda ... at a concentration of 0.1 µg/µl in ... DNA sequencing reactions using SequiTherm™ EXCEL™ II ...
BD BioCoat Matrigel Matrix 35 mm Culture Dishes Coating : BD MatrigelTM Basement Membrane Matrix ,Surface : ECM/attachment factors ,Surface area : 9.6 cm2 ,Dim nominal : 35 mm x 10 mm ,Vo...
BD BioCoat Collagen I 35 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of rat tail collagen type I....
Biology Products: