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JGH researchers help pinpoint osteoporosis genes
Date:5/3/2010

ere able to look across the whole human genome to try to identify which genes of all the genes that we inherit that seem to be responsible for osteoporosis," Dr. Richards explained. "Not only did we find 13 entirely new genes, we also demonstrated that some of these genes were related not just to bone density, but also to fracture risk itself."

Richards is optimistic that these results will bring practical benefits to patients.

"In order to better treat any condition, we need to know what causes it," he said. "We knew that one of the strongest factors in osteoporosis was genetic, but we didn't have a clear picture what those genetic factors were. This study affords us the opportunity to study the genetic mechanisms which control bone strength, and to intervene to prevent peoples' bones from getting weak. Also, if we are able to uncover more genes which influence bone strength, then we may be able to identify whole populations that require early preventive treatment."


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Contact: Mark Shainblum
mshainblum@jgh.mcgill.ca
514-340-8222 x6592
Jewish General Hospital
Source:Eurekalert

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