Navigation Links
JDRF funded study links 'hygiene hypothesis' to diabetes prevention
Date:10/6/2008

New York, NY, October 6, 2008 -- A research study funded by JDRF suggests that a common intestinal bacteria may provide some protection from developing type 1 diabetes. The findings provide an important step towards understanding how and why type 1 diabetes develops in people, and may lead to potential cures.

The study, reported this week in Nature Magazine, lends further support to the "hygiene hypothesis," that exposure to an appropriate amount and composition of bacteria may be important to living a healthy life, and that susceptibility to type 1 diabetes and other autoimmune disorders may actually be caused by a lack of exposure to certain parasites and microbes.

In the study, researchers at Yale University and the University of Chicago found that exposure to certain bacteria will trigger an immune system response in mice. That response is believed to be what prevents autoimmune disorders -- conditions where the immune system attacks healthy cells in the body. In people with type 1 diabetes, the immune system attacks the beta cells in the pancreas, stopping a person's ability to detect glucose and produce insulin. For the purposes of the study, the bacteria used were harmless microbes typically found in the human intestine. The scientists suggest that safe, measured exposure to certain bacteria may lower the risk of immune disorders.

"This study outcome gives us a new avenue to explore", said JDRF Executive Vice President of Research, Richard A. Insel, MD. "And, with type 1 diabetes in the U.S. and many countries around the world at about a 3% annual rate, every lead is significant. The research gives impetus to better understanding how the bacterial flora in our body influences host immune defenses and responses that provide resistance to the development of type 1 diabetes. This understanding may provide new therapeutic approaches to prevention."

For the study, teams led by Li Wen at Yale and Alexander V. Cher
'/>"/>

Contact: Michael Cook
mcook@jdrf.org
212-479-7510
Juvenile Diabetes Research Foundation International
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mandate for public access to NIH-funded research poised to become law
2. Irritating smells alert special cells, NIH-funded study finds
3. OSU technologies funded for development
4. JDRF-funded clinical trial demonstrates continuous glucose monitoring improves blood sugar control
5. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
6. A study by the MUHC and McGill University opens a new door to understanding cancer
7. Study begins to reveal clues to the cause and progression of sepsis
8. Clones on task serve greater good, evolutionary study shows
9. New study warns limited carbon market puts 20 percent of tropical forest at risk
10. New study examines how rearing environment can alter navigation
11. Study links cat disease to flame retardants in furniture and to pet food
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... BUFFALO, N.Y. A sleep-promoting circuit located deep in ... deep sleep. Discovered by researchers at Harvard School of ... and Biomedical Sciences, this is only the second "sleep ... to be both necessary and sufficient to produce deep ... Neuroscience , the study demonstrates that fully half of ...
(Date:9/18/2014)... "frequent flyers" program, fruit flies surely would be eligible ... increasing numbers of fruit fly research studies. One fruit ... and another is scheduled launch to the station Sept. ... December. , Fruit flies are biomedical research models studied ... organisms can reveal the basis for health and disease ...
(Date:9/18/2014)... built the first smartphone app that automatically reveals ... In other words, your smartphone knows your state ... and how that affects you. , The StudentLife ... loneliness to their academic performance, also may be ... to monitor mental health, trigger intervention and improve ...
Breaking Biology News(10 mins):No sedative necessary: Scientists discover new 'sleep node' in the brain 2Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4New Dartmouth smartphone app reveals users' mental health, performance, behavior 2New Dartmouth smartphone app reveals users' mental health, performance, behavior 3New Dartmouth smartphone app reveals users' mental health, performance, behavior 4
... , JUPITER, FL Sathyanaryanan Puthanveettil, an assistant professor ... has been awarded a pair of notable grants to ... Puthanveettil will receive $225,000 over three years from ... long-term memory of a motor protein called kinesin. In ...
... didn,t have enough to worry about from dodging poachers, ... a population of endangered markhora majestic wild goat specieshas ... Wildlife Conservation Society and partners in Tajikistan and France. ... that can reach nearly five feet in length, and ...
... melanoma, the most aggressive skin cancer, is critical because ... of Missouri researchers are one step closer to melanoma ... have a chance to form. Commercial production of a ... will soon be available to scientists and academia for ...
Cached Biology News:Scripps Research Scientist wins pair of grants to study critical component of memory 2Wildlife Conservation Society documents pneumonia outbreak in endangered markhor 2MU researcher's photoacoustic device finds cancer cells before they become tumors 2
(Date:9/19/2014)... 2014 Cereal grain scientists, quality ... gather October 5–8, 2014, for the AACC International ... Center in Providence, Rhode Island. The comprehensive scientific ... food scientists, chemists, microbiologists, nutritionists, and those interested ... management. To date, 1,000 attendees have registered for ...
(Date:9/18/2014)... 2014 Bipartisan passage this week by ... to stimulate development and commercialization of new technologies and ... leaders of SPIE, the international society for optics ... and Innovation (RAMI) Act, now moves to the full ... they are optimistic that it will win passage there ...
(Date:9/18/2014)... 18, 2014 A novel robotic system ... scanner is currently being tested as part of a ... in Boston with the aim of determining if the ... prostate cancer biopsies faster, more accurate, less costly, and ... has the potential to deliver prostate cancer therapies with ...
(Date:9/18/2014)... 2014 On Tuesday, Secretary of Energy ... Risch for National Lab Day on the Hill. The ... national laboratory system. Durbin and Risch also formally launched ... awareness of the reach of the national labs as ... address some of our nation's most pressing challenges. , ...
Breaking Biology Technology:Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3
... Reportlinker.com announces that a new ... its catalogue. , Worldwide ... Electron Microscope Market Shares, Strategies, and ... , http://www.reportlinker.com/p0153912/Worldwide-Optical-Transmission-TEM-and-Scanning-SEM-Electron-Microscope-Market-Shares-Strategies-and-Forecasts-2009-to-2015.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=prnewswire ...
... (Nasdaq: DNDN ) today announced that management will present at the following ... New York City, Tuesday, November 10, 2009, ... Phoenix, Arizona, Friday, November 13, 2009, ... Healthcare Conference, New York City, Tuesday, November ...
... NeurogesX, Inc. (Nasdaq: NGSX ), a biopharmaceutical ... therapies, announced today that Anthony DiTonno, President and Chief ... conferences in New York City: the Oppenheimer & Co. ... 2009 and the Lazard Capital Markets 6th Annual Healthcare ...
Cached Biology Technology:Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 2Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 3Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 4Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 5NeurogesX to Present at Two November Conferences 2NeurogesX to Present at Two November Conferences 3
Rabbit polyclonal to Wilms Tumor Protein ( Abpromise for all tested applications). entrezGeneID: 7490 SwissProtID: P19544...
Ku80 Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Request Info...
100 g monoclonal antibody which can immunocapture ~10 g of Complex IV from heart mitochondria. Also included are 2 mg of bovine heart mitochondria for control immunocapture....
Biology Products: