Navigation Links
JDRF awards University of Copenhagen professor with grant to conduct innovative diabetes research

Copenhagen, Denmark December 13, 2007 The Juvenile Diabetes Research Foundation, the world's largest charitable funder of type 1 diabetes research, awarded Professor Jens Hiriis Nielsen, from the University of Copenhagens Department of Medical Biochemistry and Genetics, a research grant for $495,000 to study beta cell regeneration and expansion during pregnancy with the objective of discovering new approaches for the treatment of type 1 diabetes.

The project, Beta Cell Expansion: Lessons from Pregnancy, is aimed at studying the mechanisms responsible for the increase in insulin-producing beta cells during pregnancy. Experiments with mice have shown that increased levels of pregnancy hormones are involved in the proliferation of beta cells. Dr. Nielsen will now study the effect of serum from pregnant women on human beta cell proliferation and survival in isolated islets. The successful identification of the factors in pregnant human serum and understanding the signaling pathways involved in the expansion of insulin producing beta cells may ultimately lead to new regenerative drugs and therapies for type 1 diabetes.

This award will allow us to devote our research effort to unravel the mechanisms behind the beta cell expansion in pregnancy. We will work together with experts in protein chemistry from Novo Nordisk and in bioinformatics from the Institute for Systems Biology in Seattle, as well as other scientists engaged in the JDRF funded program, said Dr. Nielsen. By identification of growth factors and signaling pathways that promote expansion of the functional beta cell mass, new drug targets may be discovered that may lead to new ways of treatment of type 1 diabetes.

The University of Copenhagens novel work on beta cell regeneration and the effect pregnancy hormones have on human islet cell production, are key steps in understanding regeneration, said Patricia Kilian, Ph.D., Therapeutic Program Director for Regeneration research at JDRF. This initiative meets a critical JDRF research goal and more importantly has the potential to create applicable cure therapeutics for type 1 diabetes patients.


Contact: Brenda Cheung
Juvenile Diabetes Research Foundation International

Related biology news :

1. The American Society of Plant Biologists announces 2007 awards
2. Singapore National Science and Technology Awards
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards nearly $23M to University of Chicago for translational research
5. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
6. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
7. NIH awards UC $9 million grant to improve patient point-of-care technologies
8. NIST announces 56 new awards for innovative technology research and development
9. USP awards verified mark to Dr. Reddys Laboratories, Ltd. ingredients
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. NIH grants $33 M in institutional development awards to 3 states
Post Your Comments:
(Date:4/15/2016)... , April 15, 2016  A new partnership ... more accurate underwriting decisions in a fraction of ... competitively priced and high-value life insurance policies to ... With Force Diagnostics, rapid testing (A1C, ... data readings (blood pressure, weight, pulse, BMI, and ...
(Date:3/31/2016)... 31, 2016   ... the "Company") LegacyXChange is excited to release ... soon to be launched online site for trading 100% ... ) will also provide potential shareholders a sense of ... to an industry that is notorious for fraud. The ...
(Date:3/22/2016)... PUNE, India , March 22, 2016 ... new market research report "Electronic Sensors Market for ... Fingerprint, Proximity, & Others), Application (Communication & ... and Geography - Global Forecast to 2022", ... consumer industry is expected to reach USD ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... TORONTO , June 23, 2016 /PRNewswire/ - ... Ontario biotechnology company, Propellon ... the development and commercialization of a portfolio of ... cancers. Epigenetic targets such as WDR5 represent an ... contribute significantly in precision medicine for cancer patients. ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. , ... tests introduced last year,” stated Bob Salter, Vice President of Regulatory and Industrial ...
(Date:6/23/2016)... 23, 2016   EpiBiome , a precision microbiome ... in debt financing from Silicon Valley Bank (SVB). The ... to advance its drug development efforts, as well as ... "SVB has been an incredible strategic partner to ... traditional bank would provide," said Dr. Aeron Tynes ...
(Date:6/23/2016)... ... June 23, 2016 , ... In a new case report published today in ... patient who developed lymphedema after being treated for breast cancer benefitted from an injection ... for dealing with this debilitating, frequent side effect of cancer treatment. , ...
Breaking Biology Technology: