Navigation Links
JDRF awards University of Copenhagen professor with grant to conduct innovative diabetes research
Date:12/13/2007

Copenhagen, Denmark December 13, 2007 The Juvenile Diabetes Research Foundation, the world's largest charitable funder of type 1 diabetes research, awarded Professor Jens Hiriis Nielsen, from the University of Copenhagens Department of Medical Biochemistry and Genetics, a research grant for $495,000 to study beta cell regeneration and expansion during pregnancy with the objective of discovering new approaches for the treatment of type 1 diabetes.

The project, Beta Cell Expansion: Lessons from Pregnancy, is aimed at studying the mechanisms responsible for the increase in insulin-producing beta cells during pregnancy. Experiments with mice have shown that increased levels of pregnancy hormones are involved in the proliferation of beta cells. Dr. Nielsen will now study the effect of serum from pregnant women on human beta cell proliferation and survival in isolated islets. The successful identification of the factors in pregnant human serum and understanding the signaling pathways involved in the expansion of insulin producing beta cells may ultimately lead to new regenerative drugs and therapies for type 1 diabetes.

This award will allow us to devote our research effort to unravel the mechanisms behind the beta cell expansion in pregnancy. We will work together with experts in protein chemistry from Novo Nordisk and in bioinformatics from the Institute for Systems Biology in Seattle, as well as other scientists engaged in the JDRF funded program, said Dr. Nielsen. By identification of growth factors and signaling pathways that promote expansion of the functional beta cell mass, new drug targets may be discovered that may lead to new ways of treatment of type 1 diabetes.

The University of Copenhagens novel work on beta cell regeneration and the effect pregnancy hormones have on human islet cell production, are key steps in understanding regeneration, said Patricia Kilian, Ph.D., Therapeutic Program Director for Regeneration research at JDRF. This initiative meets a critical JDRF research goal and more importantly has the potential to create applicable cure therapeutics for type 1 diabetes patients.


'/>"/>

Contact: Brenda Cheung
bcheung@jdrf.org
212-479-7626
Juvenile Diabetes Research Foundation International
Source:Eurekalert

Related biology news :

1. The American Society of Plant Biologists announces 2007 awards
2. Singapore National Science and Technology Awards
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards nearly $23M to University of Chicago for translational research
5. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
6. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
7. NIH awards UC $9 million grant to improve patient point-of-care technologies
8. NIST announces 56 new awards for innovative technology research and development
9. USP awards verified mark to Dr. Reddys Laboratories, Ltd. ingredients
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. NIH grants $33 M in institutional development awards to 3 states
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... SAN FRANCISCO and BANGALORE, India ... part of EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... service provider, today announced a global partnership that ... convenient way to use mobile banking and payment services. ... Mobility is a key innovation area for financial services, but ...
(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
(Date:4/15/2016)... -- Research and Markets has announced the ...  report to their offering.  ,      ... gait biometrics market is expected to grow at ... Gait analysis generates multiple variables such ... compute factors that are not or cannot be ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... ... May 05, 2016 , ... CereScan, ... the National Stroke Association during National Stroke Awareness Month in May. An ... pages throughout the month. CereScan will donate $1 up to a maximum ...
(Date:5/4/2016)... ... May 04, 2016 , ... The Children’s Tumor Foundation announced its annual month-long ... grow on nerves throughout the body. It affects 1 in 3,000 people of all ... during the month of May, as well as online activities, Neurofibromatosis Awareness Month and ...
(Date:5/3/2016)... PUNE, India , May 3, 2016 ... Type (DNA Chip (Genomics, Drug Discovery, Gene ... Chips), End user (Academics Institutes, Diagnostics Centers), ... 2020" published by MarketsandMarkets, the market is ... 2020 from USD 7.63 Billion in 2015, ...
(Date:5/3/2016)... ... 2016 , ... Flagship Biosciences, the leader in tissue ... of Directors. Dr. Gillett recently retired from Charles River Laboratories (CRL), where, in ... Officer. A board-certified veterinary pathologist, Dr. Gillett joined Charles River in 1999 through ...
Breaking Biology Technology: