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JDRF, Pfizer, Hadassah Medical and the Hebrew University announce collaboration
Date:3/21/2010

NEW YORK, March 22, 2010 The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide, said today that it will begin a diabetes research collaboration with Pfizer, Hadassah Medical Organization, and The Hebrew University of Jerusalem on drugs to replicate and regenerate insulin-producing cells in people with type 1 diabetes.

The program, under the direction of Professor Benjamin Glaser (Hadassah Medical) and Dr. Yuval Dor (Department of Developmental Biology, Institute for Medical Research Israel-Canada (IMRIC) at The Hebrew University), and in collaboration with scientists from Pfizer PharmaTherapeutics Research & Development, is jointly funded by JDRF and Pfizer.

The research team will focus on the preclinical evaluation of certain proprietary Pfizer compounds as candidates to promote beta cell replication and regeneration. Drugs that can stimulate beta cell replication and expand beta cell mass have potential as disease-modifying agents for the treatment of insulin-dependent diabetes.

The collaboration aims to provide a comprehensive biological characterization of the Pfizer compounds' potential beneficial effect on beta cell health and survival, building on unique beta cell regeneration models created by Dr. Dor and funded in part by JDRF.

"Drugs that can stimulate the replication of insulin-producing cells and expand beta cell mass have the potential to reverse type 1 diabetes," said Alan J. Lewis, Ph.D., President and Chief Executive Officer of JDRF. "This program may accelerate one of JDRF's key research goals: to find ways to restore the body's ability to make insulin."

"With this collaboration, Pfizer, Hadassah Medical Organization, The Hebrew University of Jerusalem and the JDRF are creating a unique model for how clinical and biomedical scientists in industry and academia, in collaboration with non-profit organizations, can work together for the benefit of
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Contact: Joana Casas
mcasas@jdrf.org
212-479-7560
Juvenile Diabetes Research Foundation International
Source:Eurekalert

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