Navigation Links
JCI online early table of contents: Jan. 4, 2011
Date:1/4/2011

EDITOR'S PICK: Going bald without hair follicle progenitors

Androgenetic alopecia (AGA) is a frequent form of hair loss in both men and women. However, it is more common in men, in whom it is also known as male-pattern baldness. Through the analysis of bald and non-bald scalp samples from men with AGA, a team of researchers, led by George Cotsarelis, at the University of Pennsylvania School of Medicine, Philadelphia, has gained new insight into the underlying causes of AGA. Specifically, the data indicate that a defect in the conversion of hair follicle stem cells to progenitor cells has an important role in AGA. The authors therefore suggest that further studies defining the signals responsible for the transition of stem cells to progenitor cells could provide new therapeutic targets for the treatment of AGA.

TITLE: Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells

AUTHOR CONTACT:
George Cotsarelis
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Phone: 215.898.9967; Fax: 215.573.9102; E-mail: cotsarel@mail.med.upenn.edu.

View this article at: http://www.jci.org/articles/view/44478?key=0a1481860c0b098075c7

EDITOR'S PICK: Dampening inflammation with aspirin

Inflammation is a protective response to invading microbes and tissue damage. Upon microbe clearance from the body or completion of wound healing, the inflammatory response must be dampened down. One set of molecules known to play a role in resolving the inflammatory response is the E-series resolvins. While analyzing the blood of several individuals to investigate the pathway by which E-series resolvins are generated, Charles Serhan and colleagues, at Harvar
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5 6

Related biology news :

1. TGen spin-off MedTrust Online enables cancer doctors to quickly obtain best-available information
2. Personalized medicine: Innovative online journal leads the way
3. Latin American Science Initiative Puts Tropical Rainforest Diversity Online
4. Smithsonian puts tropical Eastern-Pacific shore fishes online
5. Smithsonian puts tropical eastern Pacific shore fishes online
6. Powerful online tool for protein analysis provided pro bono by Stanford geneticist
7. New online report on massive jellyfish swarms released
8. JCI online early table of contents: Jan. 19, 2009
9. Online collaboration identifies bacteria
10. Free online toolkit provides standard measures for genome and population studies
11. K-State plant pathologists develop online teaching modules used globally
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... The Flemish plant scientist Marc Van Montagu (born 1933) ... with the American scientists Mary-Dell Chilton and Robert T. ... by the US Secretary of State, John Kerry. The ... and agriculture" - gives the award annually to one ... social importance for the quality, quantity or availability of ...
(Date:6/19/2013)... , June 19, 2013 AT&T ... the upcoming launch of the ultimate workhorse among ... Terrain™. As one of the most ruggedized phones ... NEC Terrain embodies toughened versatility and business-ready features.  ... to keep workforces moving forward, while also keeping ...
(Date:6/19/2013)... the most perfectly spherical large objects in nature may ... new study. It appears in ACS, journal Langmuir ... Julyan Cartwright, Antonio G. Checa and Marthe Rousseau point ... have perhaps the most perfectly spherical, or ball-like, shape ... without a microscope. Pearls develop as nacre (mother of ...
Breaking Biology News(10 mins):World Food Prize goes to a Belgian for the first time: The scientist Marc Van Montagu 2World Food Prize goes to a Belgian for the first time: The scientist Marc Van Montagu 3World Food Prize goes to a Belgian for the first time: The scientist Marc Van Montagu 4AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 2AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 3AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 4AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 5
... the first time anywhere, a researcher at the Hebrew University ... of neurons in the brain of a mammal. , ... Alexander Silberman Institute of Life Sciences at the Hebrew University, ... develop from an undifferentiated cellular sphere into a rich and ...
... lack a single enzyme in their brains are more adept ... figure out that their environment has changed, a team led ... , The results, appearing today in the online edition ... mechanism of learning in the brain, which might serve in ...
... imaging (MRI), radiologists can better predict the likelihood of ... cord injuries (SCI), according to a study published in ... "Our study demonstrates that the possibility and extent of ... hours after injury by rigorous assessment of MR images," ...
Cached Biology News:A first -- Hebrew University scientist observes brain cell development in 'real time' 2'Smart' mice teach scientists about learning process, brain disorders 2Researchers use MRI to predict recovery after spinal cord injury 2
(Date:6/18/2013)... 2013 DuPont welcomes 48 of the ... DuPont National AgriScience Teachers Ambassador Academy this week (NATAA) ... Md. , The NATAA “Ag Academy” is ... a special project of the National FFA Foundation ... (NAAE) . The highly recommended agriscience teachers, who ...
(Date:6/18/2013)... -- regulated information — Global biopharmaceutical company UCB, Inc. and ... launch of a new Pledge campaign for people with ... empowers the millions of Americans living with ... commitment to demand more: greater understanding of the condition, ... partial-onset seizure control.  More information is available at ...
(Date:6/18/2013)... Israel , June 18, 2013 ... Active Pharmaceutical Ingredients (APIs), generic and innovative intermediates, and finished ... that the company has been granted a United ... the US and Europe for the ... number 8,410,176 B2 is titled Intermediate Compounds and Processes ...
(Date:6/18/2013)... 18, 2013 Research ... the addition of the "Injectable Drug ... Nanoparticles], Devices [Disposables & Reusable, Fillable & ... & Therapeutics [Diabetes & Oncology] - Global ... offering.      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ...
Breaking Biology Technology:DuPont Sponsors National AgriScience Ambassador Academy 2DuPont Sponsors National AgriScience Ambassador Academy 3Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 2Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 3Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 4Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 5Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 6Mapi Pharma Granted United States Patent for Pain Relief Medication "Tapentadol" 2Injectable Drug Delivery Market by Formulations, Devices & Therapeutics - Global Forecasts to 2017 2Injectable Drug Delivery Market by Formulations, Devices & Therapeutics - Global Forecasts to 2017 3
... Selexis SA, a Swiss-based biotechnology company with technologies ... yield and stable mammalian cell lines for therapeutic ... from the Company will be participating in the ... held Jun 27-30 in Washington, D.C. at the ...
... of a new quasiparticle called the "hybrid plasmon ... photonic circuits and optical computing for the 21st ... (DOE),s Lawrence Berkeley National Laboratory (Berkeley Lab) have ... generation on-chip optical communication systems. "We ...
... Inc. (Nasdaq: AMLN ) will be presenting at the ... 2011, at 12:20 p.m. ET / 9:20 a.m. PT ... Life Sciences Conference on Wednesday, June 8, 2011, at 10:00 a.m. ... New York.  Daniel M. Bradbury, president and chief executive officer ...
Cached Biology Technology:Selexis SA to Partner and Exhibit at BIO 2011 in Washington DC 2Nanoscale waveguide for future photonics 2Nanoscale waveguide for future photonics 3Nanoscale waveguide for future photonics 4
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide...
This monoclonal antibody recognizes the light chain of human Factor XII and at 100 nM inhibits 50% of Factor XII activity. It may be used in ELISA to detect human Factor XII and in coagulation assay...
Rab 3 Immunogen: Synthetic peptide corresponding to the N-terminal region of Rab 3 protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
... Disrupts biological cells for DNA ... 96 well plates (includes 96 well ... consistent lysis across the entire plate ... wells). Can be used for ...
Biology Products: