Navigation Links
JAX publishes online tool for exploring autoimmune disease gene networks
Date:10/29/2009

Bar Harbor, Maine - Currently, 5-8% of the U.S. population is afflicted with an autoimmune disease (www.niaid.nih.gov). Many of these are chronic and require life-long care. Moreover, different autoimmune diseases aggregate within a single family, suggesting they are caused by disruptions in common biological pathways.

To help researchers investigate these common pathways, The Jackson Laboratory has published "Pathways to Discovery: Autoimmune Diseases" (www.jax.org/jaxmice/pathways/autoimmune), a unique, interactive, and publicly accessible online resource that illustrates the genetic networks involved in five common autoimmune diseases: inflammatory bowel disease, rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis.

The backbone of the new tool is five "spider-web" diagrams that depict the gene/proteins involved in two or more of the five diseases. The symbols in the diagrams represent cytokines, transmembrane receptors, enzymes, nuclear receptors, and transcriptional regulators. The resource also provides gene- and disease-specific references, links to JAX Mice strains (including inducible mouse models) that can be used to research the five diseases, and descriptions of JAX In Vivo Services for compound efficacy testing.

"Pathways to Discovery: Autoimmune Diseases" promises to accelerate the discovery of autoimmune disease mechanisms and therapeutic interventions for both new and existing targets. Check it out today at www.jax.org/jaxmice/pathways/autoimmune.


'/>"/>

Contact: Joyce Peterson
joyce.peterson@jax.org
207-288-6058
Jackson Laboratory
Source:Eurekalert  

Page: 1

Related biology news :

1. British journal publishes inorganic chemistry research of NJIT professor
2. ABC publishes monograph on scientific and clinical research of Sinupret
3. Missouri Botanical Garden publishes first catalogue of plants of the Southern Cone
4. AGI publishes transition document for next US administration
5. Nature publishes new evidence about the deep biosphere written by biogeoscientists
6. Academy publishes first biography of artist-naturalist Benjamin Waterhouse Hawkins
7. The Lancet publishes first clinical trial data of a fully bioabsorbable drug eluting stent
8. World-leading journal publishes special issue on UN/GA
9. DOE publishes update of plan: Facilities for the Future of Science: A 20-Year Outlook
10. University biologist publishes book on bird speciation
11. JCI online early table of contents: Oct. 12, 2009
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
JAX publishes online tool for exploring autoimmune disease gene networks
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/15/2016)... 15, 2016  A new partnership announced today ... underwriting decisions in a fraction of the time ... and high-value life insurance policies to consumers without ... With Force Diagnostics, rapid testing (A1C, Cotinine and ... (blood pressure, weight, pulse, BMI, and activity data) ...
Breaking Biology News(10 mins):
(Date:5/27/2016)... City, Missouri (PRWEB) , ... May 27, 2016 , ... ... Development Manager, Turf and Ornamental Products. , In his 15-year career with PBI-Gordon, Dave ... Herbicide Product Manager, where he was integral in the development and launch of many ...
(Date:5/27/2016)... NEW YORK , May 27, 2016 ... state, but investors playing in this space know that volatility ... this morning,s featured companies on ActiveWallSt.com: Synta Pharmaceuticals Corp. (NASDAQ: ... CTIC ), Lpath Inc. (NASDAQ: LPTN ), and ... now and gain access to the technical alerts for these ...
(Date:5/26/2016)... , May 26, 2016 Q BioMed ... it will be a featured presenter at the 5th Annual ... New York City at the Grand Hyatt ... , Q BioMed Inc. CEO, is scheduled to begin at ... the company,s business strategy, recent developments and outline milestones for ...
(Date:5/26/2016)... ... 26, 2016 , ... Kinder Scientific (KinderScientific.com), a leading animal ... the Company for the future. Kinder Scientific announces restructured ownership and additional ... appointed Chairman of the Board, Curtis D. Kinghorn has been appointed CEO/President and ...
Breaking Biology Technology: