Navigation Links
It's all about geometry: Protein contact surfaces hold key to cures
Date:2/1/2008

d. He and his colleagues have already published an important advance in understanding this disease, based on computations using MAPAS. These new insights can in turn open important avenues for developing new treatments.

Added Tsigelny, Were also currently using MAPAS to study Alzheimer's disease mechanisms as well as molecular models of the processes involved in kidney disease and some cancers.

The importance of the work has been recognized by a prestigious Department of Energy (DOE) Innovative and Novel Computational Impact on Theory and Experiment (INCITE) award of 1.2 million processor hours, which will allow the team to run their programs on a supercomputer at Argonne National Laboratory and extend their research on Parkinsons disease.

The researchers are also working to create a supercomputer-powered system that unites multiple programs, including MAPAS with multiple data sources, to carry out comprehensive studies of the mechanisms in diseases involving membrane-protein connections.


'/>"/>

Contact: Paul Tooby
ptooby@sdsc.edu
858-822-3654
University of California - San Diego
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Inquiring minds want to know about cotton fleahoppers
2. Misconceptions about Alzheimers varies among races, survey suggests
3. Inquiring minds want to know about cotton fleahoppers
4. Americans remain pessimistic about the environment, Stanford-AP survey finds
5. Rutgers scientists research reveals critical knowledge about the nervous system
6. High-tech helmets reveal new information about the impact of hard hits to the head
7. New study increases concerns about climate model reliability
8. Scientists find good news about methane bubbling up from the ocean floor
9. Siberian jays can communicate about behavior of birds of prey
10. Study locates cholesterol genes; finds surprises about good, bad cholesterol
11. Weird water: Discovery challenges long-held beliefs about waters special properties

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2009)...vaccine available for the H1N1 virus has been sent.... The vaccination marks the first time vaccine has...emic flu., Iowa State University,s Hank Harris, ... this summer and has been shipping preventive dose...for several weeks., The latest vaccines were shi...
(Date:11/23/2009)... -- A USDOE and USDA study concluded that 50 milli...land pasture could be converted from current uses ...itchgrass, from which biomass could be harvested f... production of a perennial grass monoculture from ...d annually is expected to require nitrogen fertili...
(Date:11/23/2009)...New Hampshire microbiologist Louis Tisa has receiv...anding of the actinorhizal plants, widespread wood...d contaminated soils. , The United States Depar...sor of molecular, cellular and biomedical sciences...etween the bacteria Frankia and Casuarina, an acti...
Breaking Biology News(10 mins):Iowa State researcher produces, ships only H1N1 vaccine available for swine 2Switchgrass produces biomass efficiently 2UNH prof. receives nearly $500,000 to research environmentally significant plants 2Study Finds Soy Safe for Men 52090 1Study Finds Soy Safe for Men 52090 2Group Health Cooperative Scored Above Regional Average in 11 of 15 Quality Measures 52086 1Group Health Cooperative Scored Above Regional Average in 11 of 15 Quality Measures 52086 2Advance Research Associates Joins DATATRAKs CRO Connect Program 28TM 29 52083 1Advance Research Associates Joins DATATRAKs CRO Connect Program 28TM 29 52083 2Advance Research Associates Joins DATATRAKs CRO Connect Program 28TM 29 52083 3Advance Research Associates Joins DATATRAKs CRO Connect Program 28TM 29 52083 4
...nderstanding of the fragile marine environment, th...t-based Centre for Environment, Fisheries & Aquacu...c alliance. , The alliance will strengthen existi...establish exciting new areas of joint research. Th... environment will influence much of the work. , T...
...ril) at the UK National Stem Cell Network Annual S...bone stem cells may be harnessed to repair the dam... osteoarthritis. , Scientists at Cardiff Universi...articular cartilage of adults, which although it c...ells, has the ability to derive into chondrocytes ...
...ell Center scientist Mark I. Friedman, PhD has bee... to pursue his work on diet and obesity. , The ... scholars in the fields of science, humanities, an...evement in the past and exceptional promise for fu...er 2,600 applicants, Friedman is one of 190 recipi...
Other Biology News:New UEA-Cefas alliance launched 2Stem cells offer cartilage repair hope for arthritis sufferers 2Monell scientist Mark Friedman awarded Guggenheim Fellowship to study diet and obesity 2
(Date:11/24/2009)...AI,Nov.24/PRNewswire-Asia/--NODPharmaceuticalsInc....llowedthepatentapplicationfor,itsnano-particleoral...ghlyefficientapproachtoincorporatepeptidesor,prote...eryofdrugs,otherwiseadministeredasinjections.NODte...nymacromoleculardrugssuchasinsulin,interferon,gro...
(Date:11/24/2009)...yefficacyendpointhasbeenmetforpatientswithadvanced...CITY,Nov.24/PRNewswire-FirstCall/-AEternaZentarisI...opharmaceuticalcompanyfocusedonendocrinetherapyand...ase2studywithitstargetedcytotoxicpeptideconjugate,...ecurrentendometrialcancer.Inapersonalizedhealthcar...
(Date:11/24/2009)...Italy,November24/PRNewswire/--HealthRoboticstodaya...thagroupofselected,investors.ThisrecentlyformedTor...oticsCanada,Inc.andwillmarket,install,andsupport,H...udesthe,revolutionaryproductofferingsi.v.STATION(T...c.willalsoprovideassistanceonan"asneeded,basis"toi...
(Date:11/23/2009)...ll. You can think of it as origami very high-tec...inois have developed a technique for fabricating t...tures from thin films by coupling photolithography...teractions. , The films, only a few microns thick...e with thicker pieces of the same material. , "Th...
Breaking Biology Technology:AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 2AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 3AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 4Health Robotics Continues its Global Expansion With December 09 ASHP's Launch of Joint Venture in Canada 2Water droplets direct self-assembly process in thin-film materials 2
...echnologies, Inc. today announced the release of ...imal component-free (ACF) and serum-free medium fo... , Vancouver, B.C. (PRWEB...day announced the release of MesenCult®-ACF Me...F) and serum-free medium for culturing human mesen...
...tart(tm) improves compliance and persistence with ... up to 53% during patients, first 100 days of ther...nd pharmacist support to alleviate stress and conf...wly - prescribed medication. , ...Pleio Health Support Systems, Inc. (Pleio) announc...
...patches containing microneedles has proven just as...amuscular, hypodermic flu immunization. A team of ...stitute of Technology believes the new microneedle... improve overall seasonal vaccination coverage in ...ience, lower cost and simpler logistics over conve...
Other Biology Technology:STEMCELL Technologies Introduces a New Animal Component-Free, Serum-Free Medium for Culturing Human Mesenchymal Stem Cells 2New Pleio Medication Adherence Service Increases Prescription Refills Up To 53% 2Flu vaccine given in microneedle skin patches proves effective in mice 2Flu vaccine given in microneedle skin patches proves effective in mice 3
5' RACE Abridged Anchor Primer from Invitrogen
His-Patch ThioFusion Expression System from Invitrogen
Mouse Anti-Human UGT2B10 Monoclonal Antibody, Unconjugated, Clone 2D9 from Novus Biologicals
Mouse Anti-Human WDR5 Monoclonal Antibody, Unconjugated, Clone 2C2 from Abnova Corporation
Biology Products: