Navigation Links
It is important to demonstrate the influence of the microenvironment in the process of metastasis
Date:12/20/2007

In the work defended at the University of the Basque Country (UPV/EHU), an in vitro culture model of human colon cancer was created in order to reproduce the gene regulation that is expressed in these cancer cells during their growth as metastasis in the liver of patients. This in vitro culture model provides a simple tool for the study and identification of the origin of the factors regulating this expression, as well as a simple form of the therapeutic evaluation for new pharmaceutical drugs that block this route.

Cancer of the colon is the third most common kind of cancer in our society. And, in many cases, the first symptoms usually appear when the disease is already in quite an advanced state. Of those colon cancer patients who suffer metastasis, approximately 45 % will develop hepatic metastasis.

It is this theme that the Gipuzkoan biologist, Ms Amaya del Villar, deals with in her PhD, recently defended at the Faculty of Medicine and Odontology at the University of the Basque Country (UPV/EHU). It is research work in which colon cancer -generated hepatic metastasis is analysed, a disease which may be propitiated by genes that are regulated by the very microenvironment or environment of the liver.

The PhD entitled Study of the genes involved in hepatic metastasis of colon cancer and which are regulated by microenvironmental factors of the liver was led by Fernando Vidal-Vanaclocha of the Department of Cell Biology and Histology at the UPV/EHU and obtained excellent cum laude. Cooperating in drawing up the doctoral thesis was the Pharmakine company and the Hepatic Surgery Unit at the Cruces Hospital in Bilbao.

Ms Amaya del Villar lvarez is a graduate in Biological Sciences from the University of Navarra and currently works for the Pharmakine company, continuing her research into cancer and metastasis.

This study aimed, on the one hand, to create an in vitro culture model of human colon cancer that would enable re
'/>"/>

Contact: Irati Kortabitarte
iratik@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Nicotinic receptors may be important targets for treatment of multiple addictions
2. Scientists discover important beauty secret for balanced skin color and tone
3. Fossilized cashew nuts reveal Europe was important route between Africa and South America
4. Researchers discover important tool in understanding differentiation in human embryonic stem cells
5. Lipids in the brain an important factor for Alzheimers disease?
6. Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
7. Stowers Institutes Xie Lab demonstrates dual intrinsic and extrinsic control of stem cell aging
8. Pourquie Lab demonstrates role of growth factor in vertebrae formation
9. Influence of sex and handedness on brain is similar in capuchin monkeys and humans
10. Heat stress influences low conception of dairy herds
11. Simulating kernel production influences maize model accuracy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... July 3, 2014, Shenzhen, China Researchers from Salk ... for the first time evaluated the safety and ... and successfully developed a new method, TALEN-HDAdV, which ... pluripotent stem cell (hiPSC). This study published online ... important theoretical foundation for stem cell-based gene therapy. ...
(Date:7/11/2014)... An international team of researchers, including scientists from the ... just a reported a major step in understanding photosynthesis, ... now maintains the oxygen in its atmosphere and which ... on earth. , The researchers report the first ... reaction, namely the step in which a specific protein ...
(Date:7/11/2014)... Researchers have pioneered a revolutionary new way to ... Virtual Finger, allows scientists to move through digital ... using the flat surface of their computer screens. ... orders of magnitude more efficient, saving time, money ... areas of experimental biology. The software and its ...
Breaking Biology News(10 mins):A new genome editing method brings the possibility of gene therapies closer to reality 2A first direct glimpse of photosynthesis in action 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... 13, 2012) The blood-brain barrier is essential for maintaining ... and isolating the brain,s specific hormonal and neurotransmitter activity from ... addition to nerve cells, the brain contains glia cells that ... blood-brain boundary is made by glia joined into an envelope ...
... DC - On January 18, 2012, Dr. Peter ... National Homeland Security Research Center in the Office ... Protection Agency, will lead a session titled "National ... national resilience to bioterrorism threats involves maximizing advanced ...
... previously un-named species of horse fly whose appearance is dominated ... honour of American pop diva, Beyonc a member of ... single, Bootylicious. , According to the Australian National Insect Collection ... ( Plinthina ) beyonceae , CSIRO,s Bryan Lessard, ...
Cached Biology News:Brain glia cells increase their DNA content to preserve vital blood-brain barrier 2Fly named in honor of Beyonce 2
(Date:7/10/2014)... (PRWEB) July 10, 2014 Product ... in very low abundance and are often “lost ... and time-consuming. , Join presenters Dr. Rowel Tobias, ... Dr. John Anders, Head of Quality at Nanotherapeutics, ... approach that can speed detection and quantitation while ...
(Date:7/10/2014)... Robert Harman, DVM, Founder and CEO of Vet-Stem, Inc., the ... relaunch of his highly informative blog, now named Stem Cells ... are Stem Cells ?” Dr. Harman’s purpose for blogging ... basics of stem cell therapy so that pet owners can ... when considering regenerative medicine. , A veterinarian by trade, Dr. ...
(Date:7/10/2014)... On July 9 Prime Minister ... Russia,s first national "Industry" award ... is developing a unique project called MabNext . ... number of innovative drugs based on monoclonal antibodies for ... place at the International Exhibition "Innoprom 2014" in Ekaterinburg. ...
(Date:7/10/2014)... to the International Atomic Energy Agency (IAEA) the ... acquiring sufficient quantities of plutonium or highly enriched ... device. The IAEA also notes that most cases ... which can be challenging to detect with most ... appearing this week in the Journal of ...
Breaking Biology Technology:Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2Sensitive detection method may help impede illicit nuclear trafficking 2
... Panacea Pharmaceuticals,Inc. announced today that BC Detect(SM), ... now available from Panacea Laboratories. BC,Detect(SM) is ... the identification,of recurrence among women successfully treated ... Panacea Pharmaceuticals, is certified under the,Clinical Laboratory ...
... of anti-infectives, to ... on pexiganan development, WELLESLEY HILLS, Mass., Oct. 17 ... of rights to pexiganan, Michael Zasloff, M.D. has joined the,company,s ... the African clawed frog while at NIH (National Institutes of,Health) ...
... October 24, at 1:30 p.m. EDT, ALAMEDA, ... ), a biopharmaceutical company developing innovative therapies,for the ... call to discuss third quarter results on Wednesday, ... PDT). Kenneth Chahine, Chief Executive,Officer, and Michael Coffee, ...
Cached Biology Technology:Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer 2Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer 3Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer 4MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 2MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 3MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 4MacroChem Announces Michael Zasloff, M.D., Ph.D. Joins Company's Scientific Advisory Board 5Avigen, Inc. Announces Third Quarter 2007 Earnings Conference Call 2
HybriWell seals securely to a microscope slide surface in seconds to enclose single or multiple specimens in a small reagent volume and eliminate evaporation....
Comp Dim: chamber diam. depth 20 2.8 mm chamber maximum volume 720 μL...
... the Easy-Titer Human IgM Assay Kit to ... and easy-to-perform assay for Human IgM that ... kit incorporates a simple mix-and-read assay that ... from 15-500 ng/ml in approximately 30 minutes. ...
AC input: 230 V...
Biology Products: