Navigation Links
It can be predicted the reaction obese patients will have to a diet

This release is available in Spanish.

The presence of increased body fat, and therefore higher levels of inflammatory substances in the blood, hinders the loss and maintenance of body weight; as shown by a research project of the University of Navarra conducted by Estbaliz Goyenechea Soto, a scientist at the School of Pharmacy.

The project, entitled "A nutrigenetic and nutrigenomic study in relation to the control of body weight and inflammation," examines how the individual genetics of obese patients can help or hinder weight loss when dieting and even influence the subsequent long term maintenance of their weight loss.

Some overweight or obese people have mutated or altered genes that initially make it difficult to lose weight and later make it easier to regain lost body weight in a period of six months or a year. This problem occurs similarly in patients who have higher levels of inflammatory substances in their blood.

This genetic predisposition, along with external and personal factors such as inadequate dietary habits or physical inactivity, predispose patients to obesity and the complications that arise from it (diabetes, hypercholesterolemia and high blood pressure) which in turn increase cardiovascular risk.

The future: customized diets

The study, conducted by the Department of Food Sciences, Physiology and Toxicology has provided new data on the genetic and plasma biomarkers that predict the response of obese patients to specific diets. The goal is to develop customized therapeutic strategies in the near future based on the genetic characteristics of each person.

A bank of biomarkers (genes and proteins) capable of predicting a person's response to weight loss would enable doctors to know, with a simple blood test, how each patient would react to different types of nutritional intervention.

The study involved 180 overweight or obese patients, who followed a hypo-caloric (low energy) diet for 8 weeks and were evaluated after six months and again a year after the end of the dietary intervention.


Contact: Oihane Lakar
Elhuyar Fundazioa

Related biology news :

1. Tropical crab invades Georgia oyster reefs -- but the long-term impact cant be predicted
2. Climate change predicted to drive trees northward
3. Global warming predicted to hasten carbon release from peat bogs
4. Lifecycles of tropical cyclones predicted in global computer model
5. Tumor growth and chemo response may be predicted by mathematical model
6. New technique captures chemical reactions in a single living cell at unprecedented resolution
7. Study helps explain how allergic reactions are triggered
8. Enzyme detectives uncover new reactions, products
9. Researchers shed new light on catalyzed reactions
10. Pitt, NETL researchers report molecular chain reaction thought to be impossible
11. Researchers observe evolution chain reaction
Post Your Comments:
(Date:10/29/2015)... , Oct. 29, 2015   MedNet Solutions , ... entire spectrum of clinical research, is pleased to announce ... Tech Association (MHTA) as one of only three finalists ... "Software – Small and Growing" category. The Tekne Awards honor ... have shown superior technology innovation and leadership. ...
(Date:10/29/2015)... , Oct. 29, 2015 Daon, a global ... it has released a new version of its ... North America have already installed ... also includes a FIDO UAF certified server component ... preparing to activate FIDO features. These customers include some ...
(Date:10/29/2015)... -- Connected health pioneer, Joseph C. Kvedar , MD, ... and wellness, and the business opportunities that arise from ... of Healthy Things . Long before health and ... Kvedar, vice president, Connected Health, Partners HealthCare, was creating ... from the hospital or doctor,s office into the day-to-day ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... QUEBEC CITY , Nov. 24, 2015 /PRNewswire/ - ... the request of IIROC on behalf of the Toronto ... this news release there are no corporate developments that ... price. --> --> ... --> . --> Aeterna Zentaris ...
(Date:11/24/2015)... ... November 24, 2015 , ... This fall, global software ... events in five states to develop and pitch their BIG ideas to improve health ... state are competing for votes to win the title of SAP's Teen Innovator, an ...
(Date:11/24/2015)... , November 24, 2015 ... recent market research report released by Transparency Market Research, ... expand at a CAGR of 17.5% during the period ... Testing Market - Global Industry Analysis, Size, Volume, Share, ... global non-invasive prenatal testing market to reach a valuation ...
(Date:11/24/2015)... SAN FRANCISCO , Nov. 24, 2015 /PRNewswire/ ... today announced that Emily Leproust, Ph.D., Twist Bioscience ... Piper Jaffray Healthcare Conference on December 1, 2015 ... Palace Hotel in New York City. ... . Twist Bioscience is on ...
Breaking Biology Technology: