Navigation Links
It can be predicted the reaction obese patients will have to a diet

This release is available in Spanish.

The presence of increased body fat, and therefore higher levels of inflammatory substances in the blood, hinders the loss and maintenance of body weight; as shown by a research project of the University of Navarra conducted by Estbaliz Goyenechea Soto, a scientist at the School of Pharmacy.

The project, entitled "A nutrigenetic and nutrigenomic study in relation to the control of body weight and inflammation," examines how the individual genetics of obese patients can help or hinder weight loss when dieting and even influence the subsequent long term maintenance of their weight loss.

Some overweight or obese people have mutated or altered genes that initially make it difficult to lose weight and later make it easier to regain lost body weight in a period of six months or a year. This problem occurs similarly in patients who have higher levels of inflammatory substances in their blood.

This genetic predisposition, along with external and personal factors such as inadequate dietary habits or physical inactivity, predispose patients to obesity and the complications that arise from it (diabetes, hypercholesterolemia and high blood pressure) which in turn increase cardiovascular risk.

The future: customized diets

The study, conducted by the Department of Food Sciences, Physiology and Toxicology has provided new data on the genetic and plasma biomarkers that predict the response of obese patients to specific diets. The goal is to develop customized therapeutic strategies in the near future based on the genetic characteristics of each person.

A bank of biomarkers (genes and proteins) capable of predicting a person's response to weight loss would enable doctors to know, with a simple blood test, how each patient would react to different types of nutritional intervention.

The study involved 180 overweight or obese patients, who followed a hypo-caloric (low energy) diet for 8 weeks and were evaluated after six months and again a year after the end of the dietary intervention.


Contact: Oihane Lakar
Elhuyar Fundazioa

Related biology news :

1. Tropical crab invades Georgia oyster reefs -- but the long-term impact cant be predicted
2. Climate change predicted to drive trees northward
3. Global warming predicted to hasten carbon release from peat bogs
4. Lifecycles of tropical cyclones predicted in global computer model
5. Tumor growth and chemo response may be predicted by mathematical model
6. New technique captures chemical reactions in a single living cell at unprecedented resolution
7. Study helps explain how allergic reactions are triggered
8. Enzyme detectives uncover new reactions, products
9. Researchers shed new light on catalyzed reactions
10. Pitt, NETL researchers report molecular chain reaction thought to be impossible
11. Researchers observe evolution chain reaction
Post Your Comments:
(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/6/2017)... SINGAPORE , May 5, 2017 ... has just announced a new breakthrough in biometric ... that exploits quantum mechanical properties to perform ... new smart semiconductor material created by Ram Group ... across finance, entertainment, transportation, supply chains and security. ...
(Date:4/17/2017)... 2017 NXT-ID, Inc. (NASDAQ: NXTD ) ... of its 2016 Annual Report on Form 10-K on Thursday April ... ... in the Investor Relations section of the Company,s website at ... at . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ROTTERDAM, the Netherlands and LAGUNA HILLS, ... that The Institute of Cancer Research, London ... will use MMprofilerâ„¢ with SKY92, SkylineDx,s prognostic tool to risk-stratify ... high-risk trial known as MUK nine . The University ... this trial, which is partly funded by Myeloma UK, and ...
(Date:10/10/2017)... ... , ... San Diego-based team building and cooking events company, Lajollacooks4u, has unveiled ... bold new look is part of a transformation to increase awareness, appeal to new ... , It will also expand its service offering from its signature gourmet cooking classes ...
(Date:10/10/2017)... Parks Associates announced today that Tom Kerber , Director ... , October 11 in Scottsdale, Arizona . Kerber will ... safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and the introduction of ...
(Date:10/9/2017)... Oct. 9, 2017  BioTech Holdings announced today ... which its ProCell stem cell therapy prevents limb ... The Company, demonstrated that treatment with ProCell resulted ... saved as compared to standard bone marrow stem ... resulted in reduction of therapeutic effect.  ...
Breaking Biology Technology: